A LITTLE KNOWN BEE PRODUCT WITH THE POTENTIAL TO BECOME A FUNCTIONAL FOOD AND NUTRITIONAL SUPPLEMENT: APILARNIL DOI Open Access
Rahşan İvgi̇n Tunca, Tülin Arslan

Uludağ Arıcılık Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Beekeeping plays a crucial role in supporting agricultural sustainability and the economy through pollination production of honey other bee products. Among these products is apilarnil, less known substance derived from drone larvae that provides health benefits. Apilarnil rich essential nutrients has been reported to have favorable effects on reproductive system, autonomic nervous system cardiovascular health. In addition its natural medicinal properties, nutritional pharmaceutical potential increasingly recognized, leading commercial apilarnil. This product very important for as it contains amino acids, fatty vitamins, minerals, hormones antioxidants. recognized complete food included various Research emphasizes androgenic, estrogenic, antioxidant immune boosting Animal studies indicate improve health, reduce stress promote growth development. It also shows promise protecting against oxidative improving general this review, information apilarnil uses compiled.

Language: Английский

Apilarnil ameliorates Bisphenol A-induced testicular toxicity in adult male rats via improving antioxidant potency and PCNA expression DOI
Mohamed H. Elashal, Aida A. Abd El‐Wahed, Mostafa Mohamed

et al.

Reproductive Toxicology, Journal Year: 2024, Volume and Issue: 125, P. 108570 - 108570

Published: March 12, 2024

Language: Английский

Citations

8
Romanian Bee Product Analysis: Chemical Composition, Antimicrobial Activity, and Molecular Docking Insights DOI Creative Commons
Silvia Pătruică, Mukhtar Adeiza Suleiman, Anca Hulea

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(10), P. 1455 - 1455

Published: May 8, 2024

Bee products are considered true wonders of nature, used since ancient times, and studied even today for their various biological activities. In this study, we hypothesise that Romanian bee from different origins (micro apiary products, lyophilised forms, commercial) exhibit distinct chemical compositions, influencing An LC-MS analysis revealed varied polyphenolic content patterns, with cumaric acid, ferulic rosmarinic quercitine identified in significant amounts across all samples. Primary anti-inflammatory evaluation phases, including the inhibition haemolysis values protein denaturation, unveiled a range protective effects on red blood cells (RBC) proteins, contingent upon sample concentration. Antimicrobial activity assessments against 12 ATCC strains 6 pathogenic isolates demonstrated varying efficacy, propolis samples showing low royal jelly forms displaying moderate effectiveness, apilarnin exhibiting good inhibitory activity, mostly Gram-positive bacteria. Notably, form emerged as most promising sample, yielding best results activities assessed. Furthermore, molecular docking was employed to elucidate potential compounds these by targeting putative bacterial fungal proteins. Results showed rutin exhibited strong binding energies interactions antimicrobial proteins bacteria (−9.7 kcal/mol −7.6 kcal/mol) fungi (−9.5 −8.1 kcal/mol). The findings study support use purposes biologically active eco-friendly proportion while providing valuable insights into mechanism action.

Language: Английский

Citations

4
Antifungal activity of different extractions of drone larvae (apilarnil) DOI
Fatma Mutlu Sarıgüzel, Sibel Sílící, Ayşe Nedret Koç

et al.

Natural Product Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 6

Published: Jan. 11, 2025

Drone larvae (DL) has many biological activities thanks to the bioactive components it contains, but there are very few studies on its antimicrobial activity. The aim of this research was determine antifungal activity DL (raw and lyophilised) water ethanol extracts against fluconazole (FLU) sensitive resistant yeast strains. 87 fungal strains obtained from clinical samples were identified by phenotypic molecular methods, broth microdilution test used for All had ethanolic extract lyophilised showed higher Total phenolic substance content antioxidant found be than other extracts. According these results, observed can attributed not only components, also synergistic effect with contains.

Language: Английский

Citations

0
Effects of Drone Brood Homogenate on Wound Healing: An Experimental Study on Rats DOI Creative Commons
Mehmet Arıcan, Meral Kekeçoğlu, Yalçın Turhan

et al.

Veterinary Medicine and Science, Journal Year: 2025, Volume and Issue: 11(2)

Published: March 1, 2025

Wound healing is one of the most interesting topics in orthopaedic surgery, and there are many studies on factors mechanisms affecting this process. To evaluated macroscopic histopathological results drone larvae homogenate (DLH) wound a full-thickness model. Thirty male wistar rats (6-8 weeks, 250 ± 50 g) were used. A uniform circular approximately 18.44 1.45 (control), 19.02 1.24 (silverdin), 19.37 1.28 mm2 was excised back each rat. They divided into control (n: 10), silverdin 10) DLH groups. DLH, collected from beehive for 3-7 days late spring ready use after homogenization lyophilization. Two mL physiological saline, silver sulfadiazine 1% applied to control, groups, respectively, thin layer that completely covered wound, repeated every 2 all groups 14 days. The condition lesions observed amount contraction granulation tissue formed lesion recorded. lesioned areas examined histopathologically. There no statistically significant difference lymphocyte, fibroblast, scar thickness, polymorphonuclear leukocyte (PMNL), minivascular density (CD34) transforming growth factor-β1 (TGF-β1) among (p = 0.771, 0.434, 0.07, 0.396). group found be higher than 0.003). average diameter (6.87 0.93 mm2) 10th day (4.39 1.15 (4.16 0.55 0.0001). has positive effect healing, especially by ensuring early formation.

Language: Английский

Citations

0
Alleviating doxorubicin-induced reproductive toxicity: protective and androgenic effects of drone larvae on sperm morphology and hormonal balance DOI

Kağan Ağan,

Salih Tunç Kaya, Aydan Fülden Ağan

et al.

Toxicological Research, Journal Year: 2025, Volume and Issue: 41(2), P. 149 - 165

Published: Feb. 1, 2025

Language: Английский

Citations

0
Royal jelly: A novel eco-friendly biotemplate for the sustainable green synthesis of antibacterial silver, iron, copper, and zinc nanoparticles DOI Creative Commons

Fatemeh-Sadat Hashemirad,

Gholamreza Kavoosi, Seyed Mohammad Mahdi Dadfar

et al.

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117797 - 117797

Published: April 1, 2025

Language: Английский

Citations

0
Protein and Amino Acid Analysis Methods in Bee Products DOI
Büşra Beltekin

Published: June 7, 2024

Bee products are natural that very important for their chemical content and biological activity. An reason the activity of bee is content. For this reason, many scientific studies carried out on products. Protein amino acids two parameters indicate whether foods rich or not. Therefore, acid protein analysis also important. In section, contents explained with examples from studies.

Language: Английский

Citations

0
A LITTLE KNOWN BEE PRODUCT WITH THE POTENTIAL TO BECOME A FUNCTIONAL FOOD AND NUTRITIONAL SUPPLEMENT: APILARNIL DOI Open Access
Rahşan İvgi̇n Tunca, Tülin Arslan

Uludağ Arıcılık Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Beekeeping plays a crucial role in supporting agricultural sustainability and the economy through pollination production of honey other bee products. Among these products is apilarnil, less known substance derived from drone larvae that provides health benefits. Apilarnil rich essential nutrients has been reported to have favorable effects on reproductive system, autonomic nervous system cardiovascular health. In addition its natural medicinal properties, nutritional pharmaceutical potential increasingly recognized, leading commercial apilarnil. This product very important for as it contains amino acids, fatty vitamins, minerals, hormones antioxidants. recognized complete food included various Research emphasizes androgenic, estrogenic, antioxidant immune boosting Animal studies indicate improve health, reduce stress promote growth development. It also shows promise protecting against oxidative improving general this review, information apilarnil uses compiled.

Language: Английский

Citations

0