Cardiometabolic Index is associated with heart failure: a cross-sectional study based on NHANES DOI Creative Commons
Zhu Xiao-ming, Yan Xu, Jie Zhang

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Dec. 9, 2024

Heart failure is a complex syndrome characterized by impaired cardiac function. Despite improvements in treatment, the prevalence of heart continues to rise. The Cardiometabolic Index (CMI), novel measure combining abdominal obesity and lipid levels, has emerged as potential predictor metabolic risk.

Language: Английский

Recent advancements in the multifaceted biomedical efficacy of triazole based metal complexes DOI
Aman Kumar,

Seema Devi,

Sanjeev Kumar

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 536, P. 216675 - 216675

Published: April 10, 2025

Language: Английский

Citations

1
Novel triazole-tethered thiazol-4(5H)-one hybrids as potential therapeutics for obesity and type 2 diabetes: in vitro, in vivo, and in silico evaluations DOI
Walaa I. El-Sofany,

Amani Toumi,

Ismail Daoud

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142577 - 142577

Published: May 1, 2025

Language: Английский

Citations

0
A Click Chemistry Approach for the Synthesis of Triazole Linked Vanillin Scaffolds as Potent Pharmacophores: Anti-Diabetic, Anti-Inflammatory, Antioxidant, Molecular Docking and ADMET Investigations DOI
Vardhaman Babagond, Kariyappa S. Katagi, Mahesh Akki

et al.

Polycyclic aromatic compounds, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24

Published: May 26, 2025

Language: Английский

Citations

0
Novel and efficient synthesis of 5-chloro-6-methoxy-3-(2-((1-(aryl)-1H-1,2,3-triazol-4-yl)methoxy)ethyl)benzo[d]isoxazole derivatives as new α-glucosidase inhibitors DOI

Ram Reddy Mudireddy,

Rambabu Gundla,

Chandra Prakash Koraboina

et al.

Biochemistry and Biophysics Reports, Journal Year: 2025, Volume and Issue: 43, P. 102074 - 102074

Published: June 5, 2025

Language: Английский

Citations

0
Importance of the CuAAC Reaction in the Synthesis of Platinum Complexes with 1,4-Disubstituted-1H-1,2,3-triazoles: A Review of Their Anticancer Activity DOI Creative Commons
Delia Hernández‐Romero, Sharon Rosete‐Luna, Enrique Méndez-Bolaina

et al.

Reactions, Journal Year: 2024, Volume and Issue: 5(4), P. 947 - 983

Published: Nov. 24, 2024

Despite multiple advances in treatment and prevention, cancer remains one of the leading causes death worldwide. Chemotherapy most effective method for treatment. However, commercial chemotherapeutic drugs have limited efficacy, severe side effects, acquired resistance. Therefore, scientific community has devoted a great effort to designing new, more effective, cheaper drugs. In this sense, copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) provide 1,4-disubstituted 1H-1,2,3-triazoles high yields without forming by-products. This reaction allows easy, efficient, functional, ordered, rapid, selective, specific joining small molecules, giving rise complex molecules. The CuACC simplifies synthesis processes, accelerating discovery new agents by allowing platinum drugs, slightly altering their structure, or creating molecules with improved properties. work shows importance CuAAC search metallodrugs possible anticancer activity.

Language: Английский

Citations

0
Cardiometabolic Index is associated with heart failure: a cross-sectional study based on NHANES DOI Creative Commons
Zhu Xiao-ming, Yan Xu, Jie Zhang

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Dec. 9, 2024

Heart failure is a complex syndrome characterized by impaired cardiac function. Despite improvements in treatment, the prevalence of heart continues to rise. The Cardiometabolic Index (CMI), novel measure combining abdominal obesity and lipid levels, has emerged as potential predictor metabolic risk.

Language: Английский

Citations

0