Synthesis of Rh-MOF/PVA-PVP nanofibers for skin cancer and infection inhibition

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: April 28, 2025

Using electrospinning for nanofiber production, we can create unique materials with multiple applications in various industries, including medical bandages and wound dressings. One of the most important features these using technique, is incorporation compounds metals into their structure. In this study, a new metal-organic framework (MOF) was synthesized from rhodium, metal significant biological potential, which then used to produce nanofibers (Rh-MOF/PVA-PVP nanofiber) by mixing polyvinyl alcohol (PVA) polyvinylpyrrolidone (PVP). The newly tested against common microbial skin pathogens cancer cells, showing inhibition. Specifically, an IC50 value 19.45 μg/mL cells MIC values ranging 4 64 μg pathogenic strains were observed. This notable inhibitory ability be attributed both physical characteristics (with specific surface area 2,348 m2/g), chemical factors, active present its rhodium (Rh) Rh-MOF/PVA-PVP has potential use developing bioactive bandages,

Language: Английский

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Novel antimicrobial agents prepared on the basis of metal-organic frameworks (MOFs) and their applications in the food field

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 105070 - 105070

Published: May 1, 2025

Language: Английский

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The role of miRNAs in pathogenesis, diagnosis, and therapy of Helicobacter pylori infection, gastric cancer-causing bacteria: Special highlights on nanotechnology-based therapy

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: 205, P. 107646 - 107646

Published: May 9, 2025

Language: Английский

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Modulated Optoelectronic Properties of MOF/CNF Bionanocomposite Films for Bacterial Growth Control under Visible Light

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: May 10, 2025

The present work reports an experimental and theoretical investigation of tuning the optoelectronic properties MIL-125-NH2 nanoparticles by grafting aromatic molecules. postsynthetic modification MOF with 3,4-dihydroxybenzaldehyde (DBA) resulted in a 23% reduction bandgap energy, from 2.71 to 2.08 eV, while increasing absorbance throughout visible region spectrum, which could be attributed stabilization due enol-imine/keto-enamine tautomerism, as supported DFT calculations. Pristine grafted MOFs were assembled into cellulose nanofibers (CNF) for preparation functional CNF-based bionanocomposites. mechanical films improved, Young's modulus 1.3 GPa CNF 7.5 film 20% loading. potential developed materials photocatalytic antimicrobial therapy was evaluated against Staphylococcus aureus (S. aureus). In vitro tests showed that both bionanocomposite pristine DBA-modified remarkably reduced bacterial growth action under light. inhibition values around 58% 72%, respectively, minimal observed dark conditions. These initial results support use wound dressings.

Language: Английский

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Enhanced antibacterial activity of self-fluorescent Zn-coordinated tryptophan nanoparticles: a mechanistic approach to study bacterial disintegration

Emergent Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 11, 2024

Language: Английский

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