Interactions Between Oral Microbiota and Cancers in the Aging Community: A Narrative Review

Cancer Control, Journal Year: 2024, Volume and Issue: 31

Published: Jan. 1, 2024

The oral microbiome potentially wields significant influence in the development of cancer. Within human cavity, an impressive diversity more than 700 bacterial species resides, making it second most varied body. This finely balanced ecosystem is vital for sustaining health. However, disruptions this equilibrium, often brought about by dietary habits and inadequate hygiene, can result various ailments like periodontitis, cavities, gingivitis, even There compelling evidence that linked to several types cancer, including oral, pancreatic, colorectal, lung, gastric, head neck cancers. review discussed critical connections between cancer members microbiota. Extensive searches were conducted across Web Science, Scopus, PubMed databases provide up-to-date overview our understanding microbiota’s role By possible microbial origins carcinogenesis, healthcare professionals diagnose neoplastic diseases earlier design treatments accordingly.

Language: Английский

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Classification and prediction of smoker melanosis in gingiva using SqueezeNet algorithms

Oral Surgery, Journal Year: 2024, Volume and Issue: 17(4), P. 327 - 335

Published: May 29, 2024

Abstract Introduction Gingival darkening, known as smokers' gingival melanosis or smoker's melanosis, is a benign symptom attributed to excessive deposition of melanin pigment. Melanin, responsible for skin, hair, and eye coloration, accumulates excessively, resulting in darkened gums. While not typically severe health concern, smokers former may worry about this aesthetic change. This study aims differentiate categorize pigmentation compared non‐smokers using deep learning‐based SqueezeNet. innovative diagnostic tool holds significant promise the medical dental fields assessing presence prognosis such pigmentations. Methods The research utilized intraoral images obtained from patients at Saveetha Dental College. Two hundred exhibiting oral were enrolled, specifically targeting those with smoking history excluding cases amalgam, metallic, physiological pigmentation, intestinal polyposis, food allergies. After applying inclusion exclusion criteria, 102 subjects selected initial pool further analysis. These classified into healthy pigmented gingiva, displaying brownish‐black pigmentation. Intraoral photographs captured subjected segmentation annotation SqueezeNet subsequent Machine learning techniques employed evaluation, including random forest, logistic Regression, naive Bayes. Results accuracy results indicate performance three different machine algorithms, namely regression, Naive Bayes, on predicting gingiva non‐smokers. Using respectively, it was discovered that 88.8% 92.6%, 93.3% 95.2%, 95.1%, 95.6%. A confusion matrix Roc graph produced. Conclusions suggest algorithms can be effective populations. ROC provide insights model's used optimize classifier's threshold prediction. Thus, allows self‐diagnose doctors diagnose their hectic clinical routines.

Language: Английский

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Bioengineering from the laboratory to clinical translation in oral and maxillofacial reconstruction

The Saudi Dental Journal, Journal Year: 2024, Volume and Issue: 36(7), P. 955 - 962

Published: May 8, 2024

Conventional techniques used in oral and maxillofacial reconstruction focus mainly on utilizing autologous tissues that have unquestionably improved function esthetics for many patients, worldwide. However, the success depends countless factors such as: donor recipient sites conditions, patient's medical history, surgeon's experience, restricted availability of high-quality autogenous or stem cells, increased surgical cost time. Lately, teaming researchers, scientists, surgeons, engineers, to address these limitations, allowed tremendous progress recombinant protein therapy, cell-based gene therapy. Over past few years, biomedical engineering has been evolving from laboratory clinical applications, replacement damaged body due trauma, cancer, congenital acquired disorders. This review provides an outlook content, benefits, recent advances, future expectations salivary glands, mucosa, dental structures, reconstruction.

Language: Английский

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Assessing shade matching capability of Omnichroma, a single shade composite in posterior restorations: an in vitro study

Journal of Medicine and Life, Journal Year: 2024, Volume and Issue: 17(8), P. 776 - 781

Published: Aug. 1, 2024

Recent composites are being developed to simplify shade matching in composite restorations. Only a limited amount of research has been conducted determine the optical performance this newly introduced area. This study investigated Omnichroma (OMN) color (a single within type-I restorations) via simulated clinical cavities. A total 72 frames were created by occupying mold with Estelite Σ Quick (ES) A1, A2, and A3 shades (n = 24). Each frame was divided into three subgroups 8) according cavity dimension (width 2, 3, 4 mm/depth 2 mm). Cavities filled Omnichroma. Color parameters calculated based on CIEDE2000 (ΔE00) using non-contact spectrophotometer. Finally, data analyzed two-way ANOVA (the Tukey HSD test) (P 0.05). The surrounding significantly affected color-matching capacity OMN < 0.0001). Groups A1 showed lowest highest amounts ΔE00, respectively. width also influenced ability 0.0001) significantly. According results, mm amount. Monochromatic did not match colors well Class I cavities posterior teeth. In cases teeth less chromatic surroundings, matched better. could better wider

Language: Английский

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Impact of bone levels on stress distribution around all-on-four concept: A 3-D finite element analysis

Journal of Stomatology Oral and Maxillofacial Surgery, Journal Year: 2024, Volume and Issue: 125(5), P. 101905 - 101905

Published: May 1, 2024

Language: Английский

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The Complementary Roles of Neurological and Musculoskeletal Physical Therapy and Regenerative Medicine: A Comprehensive Review

Medicina, Journal Year: 2024, Volume and Issue: 60(7), P. 1062 - 1062

Published: June 27, 2024

Regenerative medicine, encompassing various therapeutic approaches aimed at tissue repair and regeneration, has emerged as a promising field in the realm of physical therapy. Aim: This comprehensive review seeks to explore evolving role regenerative medicine within domain therapy, highlighting its potential applications, challenges, current trends. Researchers selected publications pertinent studies from 2015 2024 performed an exhaustive electronic databases such PubMed, Embase, Google Scholar using targeted keywords “regenerative medicine”, “rehabilitation”, “tissue repair”, “physical therapy” screen applicable according preset parameters for eligibility, then compiled key insights extracted data. Several methods that are applied particular, stem cell platelet-rich plasma (PRP), engineering, growth factor treatments, were analyzed this research study. The corresponding efficacy these recovery process also elaborated, including discussion on facilitating repair, alleviating pain, improving functional restoration. Additionally, reports challenges concerning therapies, among them standardization protocols, safety concerns, ethical issues. bears considerable adjunctive therapy physiotherapy, providing new pathways results. Although significant strides have been made interpreting techniques, further is warranted enhance establish profiles, increase access availability. Merging into structure indicates transformative alteration clinical practice, with benefit increasing patient care long-term

Language: Английский

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The effect of different intracanal irrigants on the push-out bond strength of dentin in damaged anterior primary teeth

Journal of Medicine and Life, Journal Year: 2024, Volume and Issue: 17(5), P. 536 - 542

Published: May 1, 2024

This experimental study investigated the effect of different intracanal irrigants on push-out bond strength dentin in damaged anterior primary teeth. The crowns 90 teeth were sectioned horizontally, 1 mm above cementoenamel junction (CEJ). Following canal preparation with K-files, all groups except negative control received normal saline irrigation. Canals then irrigated either 3% or 5.25% sodium hypochlorite (NaOCl), 2% 0.2% chlorhexidine (CHX) solution (except and positive controls). roots filled Metapex material covered a calcium hydroxide liner. In root canals, was applied by self-etching light-cured for 20 seconds before canals restored incrementally composite. Stereomicroscopes used to assess failure patterns. Push-out strengths (MPa ± SD) were: NaOCl (16.92 5.78), (8.96 3.55), CHX (14.76 5.56), (7.76 2.93). Significant differences seen across regarding sections (P <0.001). most frequent failures adhesive cohesive. increased compared controls. Compared controls, both significantly non-vital

Language: Английский

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