Electrochemically Active Materials for Tissue-Interfaced Soft Biochemical Sensing DOI
Xiaoyan Qian, Zehua Chen, Feng Zhang

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Tissue-interfaced soft biochemical sensing represents a crucial approach to personalized healthcare by employing electrochemically active materials monitor signals at the tissue interface in real time, either noninvasively or through implantation. These sensors can be integrated with various biological tissues, such as neural, gastrointestinal, ocular, cardiac, skin, muscle, and bone, adapting their unique mechanical environments. Sensors like conductive polymers, composites, metals, metal oxides, carbon-based nanomaterials have demonstrated capabilities applications, continuous glucose monitoring, neural activity mapping, real-time metabolite detection, enhancing diagnostics treatment monitoring across range of medical fields. Next-generation tissue-interfaced biosensors that enable multimodal multiplexed measurement markers physiological parameters could transformative for medicine, allowing high-resolution, time-resolved historical an individual's health status. In this review, we summarize current trends field provide insights into challenges future trajectory sensors, highlighting potential revolutionize medicine improve patient outcomes.

Language: Английский

Overcoming Kinetic Barriers of Remote Electrochemiluminescence on Boron-Doped Diamond via Catalytic Coreactant Oxidation DOI Creative Commons
Alessandro Fracassa, Chiara Mariani, Andrea Fiorani

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Using an Ir( iii )-based redox mediator ([Ir(sppy) 3 ] 3- ) overcomes the traditional kinetic barrier of tri- n -propylamine oxidation on BDD, enhancing ECL from Ru( ii )-labeled beads by up to 46-fold.

Language: Английский

Citations

0
Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review DOI Open Access
Kosuke Ino,

Tomas Mockaitis,

Ryota Shikuwa

et al.

Analytical Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Electrochemiluminescence (ECL) is a chemiluminescence phenomenon triggered by electrochemical reactions and widely used for (bio)chemical analyses bioimaging. Compared to fluorescence sensing, ECL sensing reduces background noise eliminating autofluorescence associated with excitation light. In addition, compared conventional imaging scanning microscopes, faster as it requires no scanning. Furthermore, unlike electrode arrays, devices can function without complex wiring, simplifying their construction. These characteristics render useful analytical tool. Recently, has been in vitro cell analysis due high demand biochips regenerative medicine, drug screening, microphysiological systems. This review focuses on recent advancements ECL-based applications the detection of H2O2, respiration activity, adhesion, lipid membranes, bipolar electrochemistry-based devices.

Language: Английский

Citations

0
Recent advance in single-molecule detection and imaging DOI
Han Yun,

Weijie Tong,

Fei Ma

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118252 - 118252

Published: April 1, 2025

Language: Английский

Citations

0
Electrochemically Active Materials for Tissue-Interfaced Soft Biochemical Sensing DOI
Xiaoyan Qian, Zehua Chen, Feng Zhang

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Tissue-interfaced soft biochemical sensing represents a crucial approach to personalized healthcare by employing electrochemically active materials monitor signals at the tissue interface in real time, either noninvasively or through implantation. These sensors can be integrated with various biological tissues, such as neural, gastrointestinal, ocular, cardiac, skin, muscle, and bone, adapting their unique mechanical environments. Sensors like conductive polymers, composites, metals, metal oxides, carbon-based nanomaterials have demonstrated capabilities applications, continuous glucose monitoring, neural activity mapping, real-time metabolite detection, enhancing diagnostics treatment monitoring across range of medical fields. Next-generation tissue-interfaced biosensors that enable multimodal multiplexed measurement markers physiological parameters could transformative for medicine, allowing high-resolution, time-resolved historical an individual's health status. In this review, we summarize current trends field provide insights into challenges future trajectory sensors, highlighting potential revolutionize medicine improve patient outcomes.

Language: Английский

Citations

0