Electrochemical-induced hydrofunctionalizations of alkenes and alkynes

Chemical Synthesis, Journal Year: 2024, Volume and Issue: 4(1)

Published: March 1, 2024

The hydrofunctionalizations of readily available alkenes and alkynes are one the most effective useful routes to afford diverse value-added compounds. Although traditional hydrofunctionalization strategies catalyzed by metal catalysts present convenient approaches, they also accompanied resource consumption environmental crisis. Electrosynthesis, as a renewable sustainable technology, has become cost- atom-efficient synthetic route. In this review, electrochemical-induced summarized presented. each section, electrochemical strategy access hydrogenation other (hydroboration, hydrosilylation, hydroalkylation, hydroalkoxylation, hydrocyanation, hydrocarboxylation, etc. ) products elaborated in detail separately. Finally, current challenges prospects for unsaturated carbon‒carbon (C‒C) bonds discussed briefly.

Language: Английский

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Electroreductive alkylations of (hetero)arenes with carboxylic acids

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 11, 2024

Carboxylic acids are widely available and generally inexpensive from abundant biomass feedstocks, they suitable generic coupling partners in synthetic chemistry. Reported herein is an electroreductive of stable versatile carboxylic with (hetero)arenes using protons as the hydrogen source. The application earth-abundant titanium catalyst has significantly improved deoxygenative reduction process. Preliminary mechanistic studies provide insights into in-situ generated ketone pathway, intermediacy generation ketyl radical alkylidene titanocene. Without necessity pressurized or stoichiometric hydride reductants, this protocol enables highly selective straightforward synthesis various functionalized structurally diverse alkylbenzenes under mild conditions. utility reaction further demonstrated through practical valuable isotope incorporation readily deuterium

Language: Английский

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Reduction of C=X to CH2

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

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