Coacervation for biomedical applications: innovations involving nucleic acids DOI Creative Commons
Kimiasadat Mirlohi, Whitney C. Blocher McTigue

Soft Matter, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 6, 2024

Coacervation emerges as a cutting-edge approach to enhance drug delivery, vaccines, and other therapeutics offer potential improvements in their efficacy. Figure created BioRender. Mirlohi, K. (2024) https://BioRender.com/c81q692.

Language: Английский

Structured protein domains enter the spotlight: modulators of biomolecular condensate form and function DOI Creative Commons

Nathaniel Hess,

Jerelle A. Joseph

Trends in Biochemical Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

3
Cell-free systems: A synthetic biology tool for rapid prototyping in metabolic engineering DOI

Kumyoung Jeung,

Minsun Kim,

Eunsoo Jang

et al.

Biotechnology Advances, Journal Year: 2025, Volume and Issue: unknown, P. 108522 - 108522

Published: Jan. 1, 2025

Language: Английский

Citations

1
Compartmentalization of multiple metabolic enzymes and their preparation in vitro and in cellulo DOI

Sayoko Ito‐Harashima,

Natsuko Miura

Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2025, Volume and Issue: unknown, P. 130787 - 130787

Published: March 1, 2025

Language: Английский

Citations

1
Coacervates as enzymatic microreactors DOI Creative Commons

Rif Harris,

Nofar Berman,

Ayala Lampel

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We review advances in coacervate-based microreactors, covering enzyme selection, recruitment strategies, microreactor compositions, and their impact on reaction kinetics.

Language: Английский

Citations

1
Polymer-engineered condensates for enzyme activation DOI Creative Commons
Tomoto Ura,

Toya Yoshida,

Tsutomu Mikawa

et al.

Polymer Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Language: Английский

Citations

0
Coacervate Droplets as Biomimetic Models for Designing Cell‐Like Microreactors DOI Creative Commons
Tsvetomir Ivanov, Thao P. Doan‐Nguyen,

Mohammed A. Belahouane

et al.

Macromolecular Rapid Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 26, 2024

Abstract Coacervates are versatile compartments formed by liquid–liquid phase separation. Their dynamic behavior and molecularly crowded microenvironment make them ideal materials for creating cell‐like systems such as synthetic cells microreactors. Recently, combinations of natural molecules have been exploited via simple or complex coacervation to create that can be used build hierarchical chemical with life‐like properties. This review highlights recent advances in the design coacervate their application biomimetic reactors cell mimicking systems. It first explores variety influence structure on controlled behavior. Then, applications coacervates reviewed, focusing how they microreactors through ability sequester provide a distinct regulatory reactions aqueous media.

Language: Английский

Citations

2
Coacervation for biomedical applications: innovations involving nucleic acids DOI Creative Commons
Kimiasadat Mirlohi, Whitney C. Blocher McTigue

Soft Matter, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 6, 2024

Coacervation emerges as a cutting-edge approach to enhance drug delivery, vaccines, and other therapeutics offer potential improvements in their efficacy. Figure created BioRender. Mirlohi, K. (2024) https://BioRender.com/c81q692.

Language: Английский

Citations

2