The
integration
of
metal
nanoparticles
and
solid
carriers
can
achieve
ideal
stability,
high
load
good
conductivity.
In
this
work,
copper
(Cu
NPs)
were
sequentially
deposited
on
a
cobalt
metal-organic
framework
(Co-MOF)
by
bonding
with
exposed
imino
groups,
followed
reduction
reaction
to
prepare
new
Cu@Co-MOF
composite.
acts
as
non-enzymatic
electrochemical
sensor
detect
glucose
(Glu)
in
an
alkaline
medium.
composite
working
electrode
Cu@Co-MOF/GCE
(GCE
=
glassy
carbon
electrode)
improves
the
electrocatalytic
activity
for
Glu
oxidation.
shows
excellent
performances
concentration
ranging
0.005~1.8
mmol∙L−1
(mM):
sensitivities
are
282.89
μA∙mM−1∙cm−2
0.005-0.4
mM
113.15
0.4-1.8
respectively
low
detection
limit
1.6
μM
(S/N
3)
selectivity
stability.
Chemosensors,
Journal Year:
2022,
Volume and Issue:
10(10), P. 416 - 416
Published: Oct. 12, 2022
A
3D
cobalt
metal–organic
framework
(Co–MOF),
[Co3(BDC)3(DMU)2],
was
utilized
to
prepare
Cu@Co–MOF
composite
in
a
deposition–reduction
process.
Cu@Co–MOF/GCE
(GCE
=
glassy
carbon
electrode)
electrode
prepared
by
“drop–coating”
method.
shows
excellent
electrocatalytic
activity
for
Glu
detection.
The
chronoamperometric
response
of
concentration
(CGlu)
displays
linear
relationships
two
CGlu
sections
with
calculated
sensitivities
282.89
μA
mM−1
cm−2
within
0.005–0.4
mM
and
113.15
0.4–1.8
Glu.
detection
limit
is
as
1.6
μM
at
S/N
3.
also
exhibits
rapid
current
response,
high
anti–interference,
stability,
repeatability
applied
detect
human
serum
orange
juice.
All
found
are
very
close
those
added
low
RSDs
recoveries.
non–enzymatic
electrochemical
sensor
has
sensitivity,
selectivity,
accuracy,
reliability.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(4), P. 492 - 492
Published: April 19, 2023
The
detection
of
small
molecules
has
attracted
enormous
interest
in
various
fields,
including
the
chemical,
biological,
and
healthcare
fields.
In
order
to
achieve
such
with
high
accuracy,
up
now,
types
biosensors
have
been
developed.
Among
those
biosensors,
enzymatic
shown
excellent
sensing
performances
via
their
highly
specific
reactions
chemical
molecules.
As
techniques
used
implement
function
electrochemical
fluorescence
mostly
for
because
advantages.
addition,
through
incorporation
nanotechnologies,
property
each
technique-based
nanobiosensors
can
be
improved
measure
harmful
or
important
accurately.
This
review
provides
interdisciplinary
information
related
developing
molecule
detection,
as
widely
enzymes,
target
molecules,
electrochemical/fluorescence
techniques.
We
expect
that
this
will
provide
a
broad
perspective
well-organized
roadmap
develop
novel
fluorescent
nanobiosensors.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 10, 2025
Abstract
The
research
and
implementation
of
portable
low-cost
analytical
devices
that
possess
high
reproducibility
ease
operation
is
still
a
challenging
task,
growing
field
importance,
within
the
research.
Herein,
we
report
concept,
design
optimization
microfluidic
device
based
on
electrochemiluminescence
(ECL)
detection
can
be
operated
without
electricity
for
purposes.
functions
exploiting
concept
streaming
potential-driven
bipolar
electrochemistry,
where
potential
difference,
generated
from
flow
an
electrolyte
through
microchannel
under
influence
pressure
gradient,
driving
force
redox
reactions.
To
our
purpose,
have
employed
such
to
drive
ECL
reaction
organic
chromophore
deposited
onto
electrode
surface
by
simply
flowing
electrolytic
solution
containing
coreactant
into
system,
successively
applied
amines
in
water.
Our
shows
satisfactory
limits
tri-n-propylamine,
demonstrating
original,
up
now
unexplored,
energy
saving
systems
with
integrated
detection.
Sensors & Diagnostics,
Journal Year:
2023,
Volume and Issue:
2(3), P. 582 - 599
Published: Jan. 1, 2023
In
this
review,
we
summarize
and
classify
the
signal
output
mode
of
DNA-based
ECL
biosensors
introduce
different
immobilization
methods
DNA
probes
on
electrodes.
Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
94(46), P. 16122 - 16131
Published: Nov. 8, 2022
A
simple
procedure
to
incorporate
enzymes
(horseradish
peroxidase,
HRP,
and
lactate
oxidase,
LOx)
within
alginate
hydrogels
is
reported
with
electrochemiluminescence
(ECL)
used
detect
the
enzymatic
reactions
corresponding
substrates.
First,
HRP
LOx
were
successfully
immobilized
into
CaCO3
microspheres,
followed
by
electrostatic
layer-by-layer
deposition
of
a
nanoshell
onto
finally
their
dispersion
solution.
The
as-prepared
was
drop
cast
glassy
carbon
electrodes
cross-linked
external
internal
gelation
methods
using
Ca2+
cations.
encapsulated
characterized
cyclic
voltammetry
kinetic
studies
performed
ECL.
results
showed
that
activity
significantly
maintained
as
result
immobilization,
values
apparent
Michaelis–Menten
constants
estimated
7.71
±
0.62
8.41
0.43
μM,
for
LOx,
respectively.
proposed
biosensors
good
stability
repeatability
an
limit
detection
5.38
0.05
0.50
0.03
μM
hydrogen
peroxide
lactic
acid,
up
28
days
from
preparation.
sensitivity
selectivity
tested
in
real
matrices
(HRP,
peroxide,
contact
lens
solution;
acid
artificial
sweat)
showing
ECL
samples.
Sensors and Materials,
Journal Year:
2023,
Volume and Issue:
35(5), P. 1785 - 1785
Published: May 24, 2023
Screen-printed
carbon
electrodes
(SPCEs)
were
modified
with
gold
particles
to
improve
luminol
electrochemiluminescence
(ECL)
in
the
presence
of
H
2
O
as
co-reactant.Gold
sizes
ranging
from
10
50
nm
successfully
deposited
by
electrochemical
technique
around
3.4%
(w/w)
on
surface.The
gold-modified
SPCE
(Au-SPCE)
increases
ECL
intensity
2.5
times
more
than
that
using
unmodified
SPCE.These
signals
also
found
be
linearly
correlated
concentration.At
an
optimum
pH
9,
1
mM
0.1
M
phosphate
buffer
solution
Au-SPCE
are
linear
concentration
range
0.5
200
µM
(R
=
0.99)
estimated
detection
limit
4.78
µM.The
developed
sensor
showed
excellent
repeatability
and
reproducibility
signals.Moreover,
milk
tap
water
samples
was
demonstrated,
indicating
is
promising
for
applications.
Electrochemistry,
Journal Year:
2024,
Volume and Issue:
92(10), P. 101007 - 101007
Published: Aug. 6, 2024
The
coupling
between
bipolar
electrochemistry
and
electrochemiluminescence
(ECL)
technologies
has
resulted
in
a
fascinating
field
of
the
academic
research,
because
advantages
both
techniques
are
often
emphasized
their
combined
form.For
instance,
light
emission
resulting
from
an
electrochemical
reaction
typical
ECL
process
can
be
exploited
for
reporting
redox
events
occurring
on
wireless
electrode
(BPE).After
introducing
concept
electrochemiluminescence,
this
comprehensive
paper
summarizes
most
recent
research
results
author
aforementioned
area
at
Tokyo
Institute
Technology
during
her
multi-year
stay
as
overseas
researcher.These
include
development
analytical
tool
based
imaging
to
map
potential
distribution
different
types
cells,
characterization
conducting
polymer
materials
ability
promote
reaction.Such
findings
assessed
relation
current
literature
scenario,
whereas
future
perspectives
also
discussed
end
manuscript.
