Organic Letters,
Journal Year:
2019,
Volume and Issue:
21(20), P. 8389 - 8394
Published: Oct. 7, 2019
C═C
bond
breaking
to
access
the
C═N
remains
an
underdeveloped
area.
A
new
protocol
for
cleavage
of
alkenes
under
nonoxidative
conditions
produce
imines
via
iron-catalyzed
nitrene
transfer
reaction
4-hydroxystilbenes
with
aryl
azides
is
reported.
The
success
various
sequential
one-pot
reactions
reveals
that
good
compatibility
this
method
makes
it
very
attractive
synthetic
applications.
On
basis
experimental
observations,
a
plausible
mechanism
also
proposed.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(11), P. 4386 - 4464
Published: Jan. 1, 2022
The
emerging
field
of
organometallic
catalysis
has
shifted
towards
research
on
Earth-abundant
transition
metals
due
to
their
ready
availability,
economic
advantage,
and
novel
properties.
In
this
case,
manganese,
the
third
most
abundant
transition-metal
in
Earth's
crust,
emerged
as
one
leading
competitors.
Accordingly,
a
large
number
molecularly-defined
Mn-complexes
been
synthesized
employed
for
hydrogenation,
dehydrogenation,
hydroelementation
reactions.
regard,
catalyst
design
is
based
three
pillars,
namely,
metal-ligand
bifunctionality,
ligand
hemilability,
redox
activity.
Indeed,
developed
catalysts
not
only
differ
chelating
atoms
they
possess
but
also
working
principles,
thereby
different
turnover
numbers
product
molecules.
Hence,
critical
assessment
molecularly
defined
manganese
terms
atoms,
reaction
conditions,
mechanistic
pathway,
significant.
Herein,
we
analyze
complexes
catalytic
activity,
versatility
allow
multiple
transformations
routes
convert
substrates
target
This
article
will
be
helpful
get
significant
insight
into
design,
aiding
design.
ChemCatChem,
Journal Year:
2019,
Volume and Issue:
12(7), P. 1891 - 1902
Published: Dec. 21, 2019
Abstract
Acceptorless
dehydrogenative
coupling
(ADC)
has
emerged
as
a
powerful
tool
in
the
chemists’
arsenal
for
construction
of
various
carbon‐carbon
and
carbon‐heteroatom
bonds.
These
protocols
are
highly
atom
economical
environmentally
benign
they
do
not
require
pre‐functionalized
starting
material
produce
only
dihydrogen
(and
water)
by‐product.
This
technique,
coupled
with
Earths’
abundant
less
toxic
manganese
catalysis,
can
prove
to
be
vital
strategy
generation
molecular
complexity
from
simple
materials.
Manganese
catalyzed
DHC
been
growing
interest,
low‐
high‐valent
catalysts
have
developed.
were
demonstrated
show
excellent
catalytic
activity
formation
carbon‐carbon,
bonds,
cascade
reactions.
In
this
mini‐review,
we
would
like
highlight
recent
progress
that
made
ADC
The Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
85(23), P. 14971 - 14979
Published: Nov. 11, 2020
Dehydrogenative
coupling-based
reactions
have
emerged
as
an
efficient
route
toward
the
synthesis
of
a
plethora
heterocyclic
rings.
Herein,
we
report
efficacious,
nickel-catalyzed
two
important
heterocycles
such
quinoline
and
quinoxaline.
The
catalyst
is
molecularly
defined,
phosphine-free,
can
operate
at
mild
reaction
temperature
80
°C.
Both
be
easily
assembled
via
double
dehydrogenative
coupling,
starting
from
2-aminobenzyl
alcohol/1-phenylethanol
diamine/diol,
respectively,
in
shorter
span
time.
This
environmentally
benign
synthetic
protocol
employing
inexpensive
rival
many
other
transition-metal
systems
that
been
developed
for
fabrication
putative
heterocycles.
Mechanistically,
dehydrogenation
secondary
alcohol
follows
clean
pseudo-first-order
kinetics
exhibits
sizable
kinetic
isotope
effect.
Intriguingly,
this
provides
example
storing
trapped
hydrogen
ligand
backbone,
avoiding
metal-hydride
formation.
Easy
regeneration
oxidized
form
under
aerobic/O2
oxidation
makes
eco-friendly
easy
to
handle.
Chemical Communications,
Journal Year:
2021,
Volume and Issue:
57(69), P. 8534 - 8549
Published: Jan. 1, 2021
Manganese
catalyzed
hydrogen
transfer
reactions
enabled
net
reductions
and
cascade
CC-
CN-bond
formation
reactions.
The
success
is
aided
by
multifunctional
ligand
design
namely
metal–ligand
bifunctionality,
hemilability,
redox
non-innocence.
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(8), P. 1602 - 1650
Published: Jan. 29, 2020
Abstract
Manganese‐catalysed
reactions
have
attracted
great
attention
recently
due
to
the
high
relative
abundance
and
cheap
eco‐friendly
behaviour.
Applications
of
manganese
catalysis
in
cross‐dehydrogenative
coupling
are
among
hottest
areas
since
90%
contributions
very
recent.
Dehydrogenation
alcohols
using
Mn‐pincer
systems
is
highly
explored
nowadays
for
cross‐coupling
synthesise
a
variety
products
Mn‐catalysed
C−H
activation,
radical
applied
dehydrogenative
couplings
various
synthons.
This
review
focuses
on
synthesis
synthetically
as
well
biologically
important
motifs
such
carbonyl
compounds,
olefins,
nitrogen
heterocycles,
amines,
imines,
etc.
manganese‐catalysed
reactions.
magnified
image
European Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
2021(26), P. 3690 - 3720
Published: June 15, 2021
Abstract
Development
in
the
area
of
acceptorless
dehydrogenation
(AD)
and
borrowing
hydrogen
(BH)
catalysis
emerge
as
one
potential
tools
for
various
C−C
C‐heteroatom
bond
forming
reactions.
Alcohols,
which
are
important
lignocellulosic
biomass
products,
act
pivotal
electrophilic
coupling
partners
such
processes
interestingly
only
H
2
or
O
is
eliminated
a
byproduct.
Initially,
was
developed
by
use
noble
metal
catalysts.
Recently,
base
metals
Mn,
Fe,
Co,
Ni
proved
to
be
environmentally
benign
inexpensive
alternatives
application
AD
BH
methods.
This
transition
catalyzed
approaches
also
allow
access
toward
plethora
structurally
heterocyclic
molecules
via
atom
economical
strategy.
Herein,
we
summarize
current
rising
expansion
heterocycles
synthesis
through
hydrogenation
European Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
2021(46), P. 6206 - 6223
Published: Nov. 4, 2021
Abstract
Acceptorless
dehydrogenative
coupling
reactions
(ADC)
and
hydrogen
transfer
strategies
(HT)
provide
a
powerful
tool
in
the
multicomponent
formation
of
N
‐
heterocycles.
A
broad
variety
complex
products
can
be
obtained
starting
from
simple,
cheap
commercially
available
reagents.
The
protocols
are
highly
atom‐efficient,
as
water,
dihydrogen,
or
some
cases
peroxide,
only
by‐products.
Moreover,
neither
further
reducing
oxidizing
agents,
nor
external
general
required.
Especially
base
metal‐catalyzed
become
ever
more
important.
Therefore,
recent
years,
various
different
manganese,
iron,
cobalt,
nickel
copper
catalysts
have
been
developed.
This
Minireview
highlights
progress
that
has
made
by
using
abundant
metal
complexes
to
promote
cyclizations
for
heterocycles
compares
their
performance
with
noble
catalyst
systems.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 29, 2024
Abstract
The
acceptorless
dehydrogenation
reaction
is
a
sustainable
and
atom‐economical
methodology
in
organic
synthesis,
resulting
the
byproducts
of
only
hydrogen
or
water.
Herein,
robust
Co−Si/CN
catalyst
(derived
from
ZIF@SiO
2
composite)
has
been
synthesized
through
one‐step
assembly
process
via
pyrolysis
etching.
This
employed
for
dehydrogenative
coupling
2‐aminoalcohols
with
secondary
alcohols,
enabling
efficient
conversion
various
substrates
into
desired
quinoline
pyridine
derivatives
yield
up
to
94
%.
