Novel BODIPY-based NIR fluorescent probe with appropriate Stokes shift for diagnosis and treatment evaluation of epilepsy via imaging ONOO− fluctuation

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 423, P. 136766 - 136766

Published: Oct. 11, 2024

Language: Английский

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Sensing Mechanism of Cysteine Specific Fluorescence Probes and Their Application of Cysteine Recognition

Chemical & Biomedical Imaging, Journal Year: 2024, Volume and Issue: 2(4), P. 250 - 269

Published: Feb. 28, 2024

Due to the biological importance of cysteine (Cys), development organic fluorescence probes for Cys has been a wide, potent, and outstanding research field in most recent years. It used as biomarker treating various diseases; therefore, developing sensing mechanism detecting is very important. In this Review, we focus on summarize specific results exciting literature regarding Cys-specific their applications recognition. Moreover, design strategy can be classified into seven reaction mechanisms, including aromatic substitution rearrangement reaction, cyclization aldehyde, Michael addition Se–N or S–S bond cleavage acrylate, metal complex nucleophilic reaction. all sections, discussions have corresponded which consist emission, color changes, detection limits deal with application recognition sites molecules. Future directions challenges proposed preparation probes.

Language: Английский

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Advancing Aggregation‐Induced Emission‐Derived Biomaterials in Viral, Tuberculosis, and Fungal Infectious Diseases

Aggregate, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

ABSTRACT Contagious diseases caused by different types of highly contagious pathogens, such as SARS‐CoV‐2, monkeypox virus, Mycobacterium tuberculosis , and human immunodeficiency could trigger global outbreaks bring a huge public health burden. Advanced diagnostic, therapeutic, preventive strategies are urgently needed to deal with the epidemic diseases. Aggregation‐induced emission (AIE) has emerged one promising candidates that exhibit tunable photophysical properties, high biocompatibility, exceptional photostability, distinguishing aggregation‐enhanced fluorescence. As result, they offer effective for diagnosis, treatment, prevention This review systematically outlined latest research progress AIE‐based biomaterials mechanisms in The versatility AIE molecules, well efficient fluorescence potential innovative combat these challenges. Thanks recent advances materials science better understanding aggregation‐induced luminogens (AIEgens), AIEgens have great provide solutions detection, By reviewing state‐of‐the‐art methods killing, agents highlighting technological developments, this outlook aims promote development new means control emerging, re‐emerging, major further activities critical area research.

Language: Английский

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A novel LD-targeting cysteine-activated fluorescent probe for diagnosis of APAP-induced liver injury and its application in food analysis

Food Chemistry, Journal Year: 2024, Volume and Issue: 456, P. 140064 - 140064

Published: June 12, 2024

Language: Английский

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Modular enantioselective assembly of multi-substituted boron-stereogenic BODIPYs

Nature Chemistry, Journal Year: 2024, Volume and Issue: 17(1), P. 83 - 91

Published: Sept. 20, 2024

Language: Английский

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