Advanced Synthesis & Catalysis,
Journal Year:
2022,
Volume and Issue:
364(7), P. 1264 - 1270
Published: Feb. 19, 2022
Abstract
Cp*Rh(III)‐catalyzed
regioselective
C−H
annulation
and
alkenylation
of
2‐pyridones
with
terminal
alkynes
have
been
developed.
The
cationic
Cp*Rh(III)
catalytic
system
containing
FeCl
3
additive
enables
1‐(2‐pyridyl)‐2‐pyridones
alkynes,
providing
efficient
access
to
5,7‐diarylated
2‐quinolinones.
reaction
pathway
can
be
switched
[Cp*RhCl
2
]
as
the
catalyst,
NaOAc
HOAc
solvent,
affording
C6‐alkenylated
in
high
yields.
These
protocols
accommodate
a
wide
range
substrates
good
functional
group
compatibility.
magnified
image
Chemical Communications,
Journal Year:
2022,
Volume and Issue:
58(29), P. 4561 - 4587
Published: Jan. 1, 2022
This
feature
article
uncovers
a
tactical
blueprint
for
the
sustainable
development
of
synthetic
manifestations
in
transition-metal
catalyzed
directing
group
assisted
multiple
annulations
(L-type,
Y-type,
and
B-type)
inert
C(arene)–H
bonds.
Chemical Communications,
Journal Year:
2021,
Volume and Issue:
58(2), P. 133 - 154
Published: Nov. 10, 2021
Herein,
the
recent
progress
of
an
annulative
alkyne-insertion
π-extension
(AAIPEX)
strategy
to
construct
opto-electronically
significant
cationic
polycyclic
heteroaromatic
compounds
(cPHACs)
is
showcased.
ChemSusChem,
Journal Year:
2023,
Volume and Issue:
16(12)
Published: March 7, 2023
Electrochemically
promoted
transition
metal-catalyzed
C-H
functionalization
has
emerged
as
a
promising
area
of
research
over
the
last
few
decades.
However,
development
in
this
field
is
still
at
an
early
stage
compared
to
traditional
reactions
using
chemical-based
oxidizing
agents.
Recent
reports
have
shown
increased
attention
on
electrochemically
functionalization.
From
standpoint
sustainability,
environmental
friendliness,
and
cost
effectiveness,
oxidation
metal
catalyst
offers
mild,
efficient,
atom-economical
alternative
chemical
oxidants.
This
Review
discusses
advances
metal-electrocatalyzed
past
decade
describes
how
unique
features
electricity
enable
economic
sustainable
way.
Angewandte Chemie International Edition,
Journal Year:
2022,
Volume and Issue:
61(42)
Published: Aug. 29, 2022
Enantioselective
Ni-catalyzed
C(sp3
)-H
bond
activation
remains
an
elusive
challenge.
Herein,
we
used
phosphine
oxide-ligated
Ni-Al
bimetallic
catalyst
to
realize
enantioselective
aliphatic
of
formamides,
providing
a
series
chiral
N-containing
heterocycles
in
40-95
%
yield
and
70-95
ee.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(19), P. 3352 - 3357
Published: May 4, 2023
Rh-catalyzed
weak
and
traceless
directing-group-assisted
cascade
C–H
activation
annulation
of
sulfoxonium
ylides
with
vinyl
cyclopropanes
as
a
coupling
partner
have
been
accomplished
to
furnish
functionalized
cyclopropane-fused
tetralones
at
moderate
temperature.
The
C–C
bond
formation,
cyclopropanation,
functional
group
tolerance,
late-stage
diversifications
drug
molecules,
scale-up
are
the
important
practical
features.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(20), P. 4212 - 4217
Published: May 14, 2024
An
unusual
rhodium-catalyzed
C–H
activation/Lossen
rearrangement/oxa-Michael
addition
tandem
cyclization
has
been
achieved
along
with
a
tunable
well-known
activation/[4
+
2]
annulation,
leading
to
regio-,
chemo-,
and
diastereoselective
access
diverse
pentacyclic
α-carbolines
β-carboline-1-one
derivatives
in
moderate
good
yields
significant
anticancer
activity.
