Acylsilanes as Weakly Coordinating Directing Groups for Metal-Catalyzed C–H Functionalization

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 6881 - 6894

Published: April 14, 2025

Language: Английский

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C–H Functionalization as a Powerful Method for Direct Synthesis of Lactones

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 9013 - 9034

Published: May 13, 2025

Language: Английский

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Construction of carbazole-based unnatural amino acid scaffolds via Pd(ii)-catalyzed C(sp³)–H functionalization

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(21), P. 4391 - 4414

Published: Jan. 1, 2022

Synthesis of racemic and enantiopure carbazole-based unnatural amino acid motifs was accomplished via diastereoselective Pd( ii )-catalyzed β-C(sp 3 )–H functionalization.

Language: Английский

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Site‐Selective C−H Arylation of Diverse Arenes Ortho to Small Alkyl Groups

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(39)

Published: July 13, 2022

Catalytic systems for direct C-H activation of arenes commonly show preference electronically activated and sterically exposed sites. Here we that a range functionally rich pharmaceutically relevant arene classes can undergo site-selective arylation ortho to small alkyl substituents, preferably endocyclic methylene groups. The is experimentally supported as being the selectivity-determining step, while computational studies transition state models indicate relevance non-covalent interactions between catalyst group substrate. Our results suggest C(sp

Language: Английский

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Structural effects of the carboxylate anion on Ru-catalyzed C—H arylation of (hetero)aromatic substrates containing N-donor directing group

Russian Chemical Bulletin, Journal Year: 2024, Volume and Issue: 73(3), P. 497 - 504

Published: March 1, 2024

Language: Английский

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