Chiral P,N,N‐Ligands for Asymmetric Hydrogenation DOI
Dinghua Liang, Chuan‐Jin Hou, Qi Li

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(10), P. 2165 - 2185

Published: April 9, 2024

Abstract The chiral P,N,N‐ligands represented a new type of tridentate ligand developed in recent years and displayed wide utilities asymmetric catalysis. In the past decades, numerous with ferrocene, phenethylamine spiro backbones were synthesized by addition an aminopyridine, imidazole or diamines coordinating group. These showed excellent performance ruthenium, iridium, manganese, cobalt‐catalyzed hydrogenations. A range substrates, including simple ketones, α‐halogenated α‐hydroxy α‐ β‐amino keto‐ ones, α‐, γ‐, δ‐keto acids, β‐keto amides, β‐ esters, β‐enones, olefins, imines, quinolines indoles, could be hydrogenated to afford corresponding products high yields enantioselectivities. this review, progress on hydrogenation C=O, C=N, C=C bonds was summarized.

Language: Английский

Discovery, engineering, and applications of the ketoreductases from Metabacillus lacus in the synthesis of chiral (Hetero)aryl alcohols DOI
Shuling Zhang, Yuqing Zhang, Weixi Kong

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 511, P. 161964 - 161964

Published: March 28, 2025

Language: Английский

Citations

1
Chiral P,N,N‐Ligands for Asymmetric Hydrogenation DOI
Dinghua Liang, Chuan‐Jin Hou, Qi Li

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(10), P. 2165 - 2185

Published: April 9, 2024

Abstract The chiral P,N,N‐ligands represented a new type of tridentate ligand developed in recent years and displayed wide utilities asymmetric catalysis. In the past decades, numerous with ferrocene, phenethylamine spiro backbones were synthesized by addition an aminopyridine, imidazole or diamines coordinating group. These showed excellent performance ruthenium, iridium, manganese, cobalt‐catalyzed hydrogenations. A range substrates, including simple ketones, α‐halogenated α‐hydroxy α‐ β‐amino keto‐ ones, α‐, γ‐, δ‐keto acids, β‐keto amides, β‐ esters, β‐enones, olefins, imines, quinolines indoles, could be hydrogenated to afford corresponding products high yields enantioselectivities. this review, progress on hydrogenation C=O, C=N, C=C bonds was summarized.

Language: Английский

Citations

6