Latest progress in proton-conducting hydrogen-bonded organic frameworks
Jin-Qi Qiao,
No information about this author
Shuai-Wu Zuo,
No information about this author
Zifeng Li
No information about this author
et al.
Inorganic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(20), P. 5856 - 5884
Published: Jan. 1, 2023
The
latest
progress
of
proton-conductive
HOFs
in
terms
preparation,
structural
characteristics,
proton
conductivity,
and
proton-conducting
mechanism
are
presented.
future
trends
design
ideas
also
highlighted
prospected.
Language: Английский
Rh(III)-Catalyzed Fabrication of [4,3,1]-Bridged Azaheterocycles using Quinone Monoacetals
Sushma Naharwal,
No information about this author
Narendra Dinkar Kharat,
No information about this author
Siva S. Panda
No information about this author
et al.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: June 5, 2025
A
rhodium-catalyzed
annulation
strategy
for
the
fabrication
of
cyclohexanone-bridged
indazolones
and
other
related
diazole-ones
diazine-ones
was
established
using
quionone
monoacetals
under
mild
conditions.
On
hand,
use
4-hydroxy-4-methylcyclohexa-2,5-dienone
optimized
Rh-conditions
produced
an
ortho-CAr-arylated
product
in
moderate
reactivity.
Mechanistic
studies
suggested
that
coupling
proceeded
via
one-pot
C-H
activation-Michael/hetero-Michael
additions
into
enone
moiety.
Interestingly,
[4,3,1]-bridged-1,2-dihydro-3H-indazol-3-ones
underwent
unexpected
migratory
aromatization
acidic
condition
to
produce
3-hydroxy-14H-benzo[c]indazolo[1,2-a]cinnolin-14-ones
high
yields.
Language: Английский
Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library
Yanrui Suo,
No information about this author
Kaige Li,
No information about this author
Xing Yi Ling
No information about this author
et al.
Bioconjugate Chemistry,
Journal Year:
2024,
Volume and Issue:
35(8), P. 1251 - 1257
Published: Aug. 8, 2024
The
DNA-encoded
library
(DEL)
is
a
robust
tool
for
chemical
biology
and
drug
discovery.
In
this
study,
we
developed
DNA-compatible
light-promoted
reaction
that
highly
efficient
plate-compatible
DEL
construction
based
on
the
formation
of
indazolone
scaffold.
Employing
high-efficiency
approach,
constructed
featuring
an
core,
which
enabled
identification
novel
series
ligands
specifically
targeting
E1A-binding
protein
(p300)
after
selection.
Taken
together,
our
findings
underscore
feasibility
reactions
in
synthesis
unveil
promising
avenues
developing
p300-targeting
inhibitors.
Language: Английский
Theoretical investigation of Cp*Rh(III)-catalyzed allylation and cyclization reactions of 1-arylindazolones with carbonates
Na Kang,
No information about this author
Wei Wei,
No information about this author
Zeng‐Xia Zhao
No information about this author
et al.
Chemical Physics Letters,
Journal Year:
2024,
Volume and Issue:
848, P. 141395 - 141395
Published: June 4, 2024
Language: Английский
Rh(III)-catalyzed [4 + 1] annulation of 1-arylindazolones with alkynyl cyclobutanols: access to indazolo[1,2-a]indazolones
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(32), P. 6500 - 6505
Published: Jan. 1, 2024
A
convenient
and
efficient
synthesis
of
structurally
diverse
indazolo[1,2-
a
]indazolones
via
Rh(
iii
)-catalyzed
[4
+
1]
annulation
1-arylindazolones
with
alkynyl
cyclobutanols
has
been
achieved
by
combining
C–H
C–C
bond
cleavage.
Language: Английский