Total synthesis of bicyclomahanimbine by Cu(ii)-promoted photoredox process DOI Creative Commons
Shilpa Dangar,

T. Roy,

Suman Noskar

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(41), P. 30110 - 30115

Published: Jan. 1, 2024

Since the isolation of carbazole alkaloids, synthetic chemists have witnessed an upsurge in research them due to their potential pharmacological properties. Our approach shows total syntheses five such biorelevant pyrano-[3,2

Language: Английский

Electricity-driven, oxidative C–H selenylative and tellurylative annulation of N-(2-alkynyl)anilines: sustainable synthesis of 3-selanyl/tellanylquinolines DOI Creative Commons

Ainala Naresh,

H. Sai Keerthana,

Nilanjana Mukherjee

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(55), P. 7057 - 7060

Published: Jan. 1, 2024

A metal- and oxidant-free, electricity-driven C–H selenylative tellurylative annulation of N -(2-alkynyl)anilines with diorganyl dichalcogenides is developed to access 3-chalcogenylquinolines.

Language: Английский

Citations

5
Electrochemically Driven Chalcogenative Cyclization of 2-Alkynyl Aryl Oxime: Access to Functionalized Isoquinolines DOI
Jiajun Hu, Bo Li,

Feng Xiong

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

A transition-metal-free electrochemical chalcogenative cyclization of 2-alkynyl aryl oxime with dichalcogenides has been established to assemble valuable 4-organochalcogen isoquinolines concisely. This protocol proceeds via constant electrolysis in a user-friendly undivided cell setup. It circumvents the necessity transition metal catalysts, chemical oxidants, and harsh reaction conditions. The practical utilities current were illustrated by excellent functional group tolerance, remarkable regio-selectivity, easy scalability, mild conditions, transformable isoquinoline products.

Language: Английский

Citations

0
Electrosynthesis of Highly Functionalized Quinolines through Radical Annulation–Polar Addition Cascade DOI
Suman Kumar Saha,

Samrat Mallick,

Aritra Nath

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(35), P. 7330 - 7335

Published: Aug. 22, 2024

Synthesis of diversely functionalized quinoline-2-carboxylates is illustrated through electrochemical cross-dehydrogenative coupling between N-aryl glycinates and methylenecyclopropanes. An extensive range distinct functionalities well-compatible under these transition-metal- oxidant-free mild conditions, contributing to a broad substrate scope practical applicability. Cyclic voltammetric measurements control experiments suggested formal [4 + 2] cycloaddition involving radical intermediates, followed by cyclopropyl ring opening nucleophilic polar addition, consecutively fabricating C–C C–N bonds.

Language: Английский

Citations

3
Tunable Electrochemical Diverse Sulfurization of Sulfoxonium Ylides with Disulfides DOI
Xinwei Hu,

Kaihui Zhong,

Zhixiong Ruan

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(65), P. 8573 - 8576

Published: Jan. 1, 2024

An electrochemical protocol for the synthesis of sulfursulfoxonium ylides and 1,3-dithioketals by reacting sulfoxonium with disulfides has been developed under simple mild conditions. By changing solubility raw materials dielectric parameters electrolyte, sulfurization enabled a selective dehydrogenation C-S construction 1,3-dithioketals. The transformation is an ideal approach to prepare organosulfur reagents broad functional group tolerance as well high selectivity, which leads vicinal difunctionalized compounds.

Language: Английский

Citations

1
Electrosynthesis of Cyclic Isoureas and Ureas Through Contiguous Heterofunctionalizations DOI

Laxmikanta Sing,

Jhilik Dutta,

Sayan Ghosh

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(16), P. 11323 - 11333

Published: July 27, 2024

An efficient synthetic protocol for the selenylated cyclic isoureas was developed using electrochemical activation of diselenides. This sustainable approach permitted transition metal and chemical oxidant-free difunctionalization olefins overall access to distinct 1,2,3 triheterofunctionalized carbon skeletons. Excellent functional group tolerance noticed, allowing synthesis a series isourea derivatives. In addition, an acid-triggered skeletal isomerization facilitated urea derivatives from corresponding isoureas. Mechanistic investigations, along with voltammetric studies, enabled postulation reaction mechanism.

Language: Английский

Citations

1
Recent advances in electrochemically enabled construction of indoles DOI
Yu Zheng,

Chunxi Chen,

Yanju Lu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(65), P. 8516 - 8525

Published: Jan. 1, 2024

This review summarizes recent advances in the electrochemically enabled construction of indoles from non-indole-based precursors and their underlying mechanisms.

Language: Английский

Citations

0
Total synthesis of bicyclomahanimbine by Cu(ii)-promoted photoredox process DOI Creative Commons
Shilpa Dangar,

T. Roy,

Suman Noskar

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(41), P. 30110 - 30115

Published: Jan. 1, 2024

Since the isolation of carbazole alkaloids, synthetic chemists have witnessed an upsurge in research them due to their potential pharmacological properties. Our approach shows total syntheses five such biorelevant pyrano-[3,2

Language: Английский

Citations

0