Vanadium‐Catalyzed Atroposelective Coupling of Arenols and Application in the Synthesis of Polycyclic Heteroaromatics ( PHAs ) DOI
Mohamed S. H. Salem, Shinobu Takizawa

Published: Oct. 18, 2024

Chiral vanadium complexes, featuring a Schiff base ligand and metal center, have garnered attention as environmentally benign catalysts facilitating the generation of axially chiral molecules. This chapter explores recent advancements in vanadium-catalyzed oxidative coupling arenols their applications synthesizing polycyclic heteroaromatics (PHAs). Through detailed investigations, highlights significant role complexes enabling chemo-, regio-, and/or enantioselective CC bondforming reactions to construct atropisomers. Beyond catalysis, it also delves into these atroposelective synthesis heterocyclic nanographenes, including helicenes dehydrohelicenes, renowned for favorable optical properties.

Language: Английский

Dialkyloxyphenyl hybrids as PDE4B inhibitors: Design, synthesis, in vitro/in vivo anti-inflammatory activity and in silico insights DOI
Aya M. Almatary, Mohamed S. H. Salem, Mohamed R. Elnagar

et al.

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108511 - 108511

Published: April 1, 2025

Language: Английский

Citations

0
Vanadium‐Catalyzed Atroposelective Coupling of Arenols and Application in the Synthesis of Polycyclic Heteroaromatics ( PHAs ) DOI
Mohamed S. H. Salem, Shinobu Takizawa

Published: Oct. 18, 2024

Chiral vanadium complexes, featuring a Schiff base ligand and metal center, have garnered attention as environmentally benign catalysts facilitating the generation of axially chiral molecules. This chapter explores recent advancements in vanadium-catalyzed oxidative coupling arenols their applications synthesizing polycyclic heteroaromatics (PHAs). Through detailed investigations, highlights significant role complexes enabling chemo-, regio-, and/or enantioselective CC bondforming reactions to construct atropisomers. Beyond catalysis, it also delves into these atroposelective synthesis heterocyclic nanographenes, including helicenes dehydrohelicenes, renowned for favorable optical properties.

Language: Английский

Citations

0