Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water DOI
Fabrice Gallou, Lutz Ackermann, Julia Struwe

et al.

Synlett, Journal Year: 2024, Volume and Issue: 35(08), P. 903 - 907

Published: Feb. 14, 2024

Abstract The manganese(I)-catalyzed allylation of the amino acid tryptophan is realized under exceedingly mild conditions using water as a sustainable and non-hazardous reaction medium, instead classical organic solvents, with great potential for green chemistry. Synthetically useful α,β-unsaturated esters can be accessed by Morita–Baylis–Hillman (MBH) adducts following fast C–H activation approach. robustness this procedure reflected kinetic analysis at different temperatures reduced catalyst loadings are employed.

Language: Английский

Transition metal-free thiophene construction in pure water by multiplied C-H functionalization with enaminones and elemental sulfur DOI Creative Commons
Lihong Tian, Jie‐Ping Wan, Yunyun Liu

et al.

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

5
Theoretical Studies of Molecular Reactions at the Air–Water Interface: Recent Progress and Perspective DOI
Jing Kang,

Shixuan Wang,

Chenruyuan Li

et al.

Wiley Interdisciplinary Reviews Computational Molecular Science, Journal Year: 2025, Volume and Issue: 15(3)

Published: May 1, 2025

ABSTRACT Water microdroplets have been shown to possess unique properties. For instance, compared bulk water, can accelerate chemical reactions by several orders of magnitude and trigger that cannot occur in water. These phenomena generated significant interest various fields like atmospheric science, green synthesis, materials preparation. properties are associated with at the air–water interface; however, underlying mechanisms remain unclear. Studying microscopic details interface remains a substantial experimental challenge. Meanwhile, molecular dynamics (MD) simulations related computational methods provide powerful tools for studying interface. This review aims summarize processes from perspective theoretical simulations. First, we discuss physical Subsequently, systematically introduce simulation strategies four categories interfacial reactions: (a) near‐barrierless reactions, (b) some energy barriers, (c) employing high‐level quantum methods, (d) photochemical reactions. Finally, focus on simulating thermal interface, particular emphasis chemistry. The discussed involve Criegee intermediates, nitrogen‐containing compounds, chlorine‐containing while include H 2 O phenol. results here enable an improved understanding as well processes.

Language: Английский

Citations

0
Palladium complexes of N,O‐bidentate ligands bearing N‐oxide units as simple and efficient catalysts for Suzuki–Miyaura reaction of aryl halides with arylboronic acids DOI
Xuefeng Jia, Xianqiang Huang

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(7)

Published: May 16, 2024

Palladium‐catalyzed Suzuki–Miyaura reaction is an important synthetic strategy for the synthesis of biaryl compounds. This work describes that palladium complexes with N,O‐bidentate ligands bearing N‐oxide units from cyclic secondary amines were used as highly efficient catalysts reactions aryl halides arylboronic acids. The exhibited good functional group compatibility, high yields, and mild conditions. More importantly, these N,O‐coordinated could be easily prepared displayed excellent catalytic performance this classic C sp2 –C coupling in very short time.

Language: Английский

Citations

2
From Aldehyde to Ketone via Water‐Accelerated Molybdenum‐Photocatalysis DOI
Jiaolong Meng,

Yixin Jia,

Chengliang Li

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: 16(21)

Published: July 16, 2024

Abstract The efficient “on water” protocol was developed by employing molybdenum‐based polyoxometalate [N(C 4 H 9 ) ] 2 [Mo 6 O 19 as the photocatalyst. This water‐accelerated photoinduced process affords versatile ketones from aldehydes straightforwardly, showcasing exceptional substrate generality. Its applicability to life‐related molecules such amino acids, peptides, and sugars, further demonstrates its potential for bioorthogonal application. mechanistic investigation highlights hydrogen atom transfer (HAT) between excited‐state POM benzaldehyde acyl radical formation. highly reactive is readily trapped Michael acceptor, thereby enabling subsequent C−H functionalization. Highly gram‐scale flow operation underlines industrial of this transformative strategy.

Language: Английский

Citations

1
Boosting catalytic activity of π-π interactions-stabilized PdNPs for water-mediated Suzuki couplings of aryl chlorides DOI

Ze‐Kun Tao,

Qinggang Zhang,

Qian Xie

et al.

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: 55, P. 105313 - 105313

Published: Oct. 22, 2024

Language: Английский

Citations

1
Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water DOI
Fabrice Gallou, Lutz Ackermann, Julia Struwe

et al.

Synlett, Journal Year: 2024, Volume and Issue: 35(08), P. 903 - 907

Published: Feb. 14, 2024

Abstract The manganese(I)-catalyzed allylation of the amino acid tryptophan is realized under exceedingly mild conditions using water as a sustainable and non-hazardous reaction medium, instead classical organic solvents, with great potential for green chemistry. Synthetically useful α,β-unsaturated esters can be accessed by Morita–Baylis–Hillman (MBH) adducts following fast C–H activation approach. robustness this procedure reflected kinetic analysis at different temperatures reduced catalyst loadings are employed.

Language: Английский

Citations

0