Killing Two Crises with One Spark: Cold Plasma for Antimicrobial Resistance Mitigation and Wastewater Reuse DOI Open Access
José Gonçalves, João Pequeno, Israel Díaz

et al.

Water, Journal Year: 2025, Volume and Issue: 17(8), P. 1218 - 1218

Published: April 18, 2025

Global water scarcity and antimicrobial resistance (AMR) represent two escalating crises that urgently demand integrated effective solutions. While wastewater reuse is increasingly promoted as a strategy to alleviate scarcity, conventional treatment processes often fail eliminate persistent contaminants antibiotic-resistant microorganisms. Cold plasma (CP), non-thermal advanced oxidation process, has demonstrated the strong potential simultaneously inactivate pathogens degrade micropollutants. CP generates diverse mix of reactive oxygen nitrogen species (ROS RNS), well UV photons charged particles, capable breaking down complex inducing irreversible damage microbial cells. Laboratory studies have reported bacterial log reductions ranging from 1 >8–9 log10, with Gram-negative such E. coli Pseudomonas aeruginosa showing higher susceptibility than Gram-positive bacteria. The inactivation endospores mixed-species biofilms also been achieved under optimized conditions. Viral studies, including MS2 bacteriophage norovirus surrogates, >99.99%, exposure times short 0.12 s. further shown capacity antibiotic residues ciprofloxacin sulfamethoxazole by >90% reduce ARGs (e.g., bla, sul, tet) in hospital wastewater. This perspective critically examines mechanisms current applications treatment, identifies operational scalability challenges, outlines research agenda for integrating into future frameworks targeting AMR mitigation sustainable management.

Language: Английский

Killing Two Crises with One Spark: Cold Plasma for Antimicrobial Resistance Mitigation and Wastewater Reuse DOI Open Access
José Gonçalves, João Pequeno, Israel Díaz

et al.

Water, Journal Year: 2025, Volume and Issue: 17(8), P. 1218 - 1218

Published: April 18, 2025

Global water scarcity and antimicrobial resistance (AMR) represent two escalating crises that urgently demand integrated effective solutions. While wastewater reuse is increasingly promoted as a strategy to alleviate scarcity, conventional treatment processes often fail eliminate persistent contaminants antibiotic-resistant microorganisms. Cold plasma (CP), non-thermal advanced oxidation process, has demonstrated the strong potential simultaneously inactivate pathogens degrade micropollutants. CP generates diverse mix of reactive oxygen nitrogen species (ROS RNS), well UV photons charged particles, capable breaking down complex inducing irreversible damage microbial cells. Laboratory studies have reported bacterial log reductions ranging from 1 >8–9 log10, with Gram-negative such E. coli Pseudomonas aeruginosa showing higher susceptibility than Gram-positive bacteria. The inactivation endospores mixed-species biofilms also been achieved under optimized conditions. Viral studies, including MS2 bacteriophage norovirus surrogates, >99.99%, exposure times short 0.12 s. further shown capacity antibiotic residues ciprofloxacin sulfamethoxazole by >90% reduce ARGs (e.g., bla, sul, tet) in hospital wastewater. This perspective critically examines mechanisms current applications treatment, identifies operational scalability challenges, outlines research agenda for integrating into future frameworks targeting AMR mitigation sustainable management.

Language: Английский

Citations

0