The evolving reality of digital health DOI Creative Commons

Nana Bit-Avragim,

Jean Bousquet,

Stefano Cantù

et al.

Digital Health, Journal Year: 2024, Volume and Issue: 10

Published: Jan. 1, 2024

Myriad digital health interventions, applications, devices and technologies have, are, being developed to help refine personalise medicine from the patient, healthcare professional (HCP), system industry perspectives. At a gathering of leaders in health, discussion included current landscape such tools (DHTs), with specific examples cardiology respiratory medicine, both benefits sometime downfalls tools. While DHTs can patients HCPs detect monitor conditions, experts discussed how adoption may be hampered by issues as access technology; data privacy security concerns; technology integration into systems; cost reimbursement; lack guidelines regulatory hurdles. The suggested solutions issues, including wider availability ‘booths’ local patient; easy understand use phone applications; patient HCP incentives clear paths within system. These should aid shared decision-making and, ultimately, streamline for all.

Language: Английский

MASK‐air® direct patient data support the ARIA‐MeDALL hypothesis on allergic phenotypes DOI Creative Commons
Jean Bousquet, Bernardo Sousa‐Pinto, Frederico S. Regateiro

et al.

Allergy, Journal Year: 2023, Volume and Issue: 78(10), P. 2790 - 2794

Published: Aug. 11, 2023

The concept of 'one-airway-one-disease', based on the links between upper and lower airway allergic diseases,1 may be an oversimplification. ARIA-MeDALL (Allergic Rhinitis its Impact Asthma-Mechanisms Development ALLergy) hypothesis—based genomic, epidemiologic clinical findings—proposed that rhinitis alone (R) a distinct entity from asthma multimorbidity (A + R), with therapeutic relevance.2 However, hypothesis has not been tested using real-world data. aim this study was therefore to assess differences in symptoms medications R A data MASK-air®, freely available mHealth app. methods are fully described online supplement. Briefly, previous study, k-means cluster analysis, we identified three groups MASK-air® users: those having 'probable asthma', 'possible asthma' or 'no evidence (R).4 In assessed (2015–2020) cross-sectionally compared patients (i) their maximum median reported visual analogue scale (VAS) values for global allergy symptoms, nasal, ocular as well impact work,3 (ii) combined symptom-medication score (allergy-CSMS5) (iii) medication component allergy-CSMS. We performed sensitivity analysis sample physician-diagnosed current asthma, past no asthma. Finally, longitudinally users frequency complete weeks displaying well-controlled, partly-controlled, variably-controlled uncontrolled rhinitis. analysed 3797 25 countries (256,839 days) (Table S1 online, Figure online). total 1733 provided (14,409 weeks). Patients displayed meaningfully higher VAS allergy-CSMS than 1). were moderate–high eye, work There meaningful when treatments groups: more asthma'. Robust results obtained subanalysis 282 enrolled by physicians (Tables S2 S3 levels each country >100 2). For levels, moderate large observed all comparing versus Small found most percentage controlled ranged 62.8% ('possible asthma') 80.0% ('no asthma'), while partly-controlled 12.6% 27.9% S4 app, that, comparison R, display nasal increased use CSMS individually different countries, suggesting generalisability finding. Although some associated high effect sizes there have user-/day-related selection biases information (e.g. classification), these overall support existence control considering R. Overall, although excluding other hypotheses, is line hypothesis. Clinically, supports assessment possibility severe supported EU grants (POLLAR, EIT Health; Structural Funds, Twinning, EIP AHA, H2020 Horizon Europe) educational Mylan-Viatris, ALK, GSK, Novartis Uriach. JB responsible design, manuscript writing (original draft). BSP RJV remaining authors collection critical revision editing manuscript. None. reports personal fees Cipla, Menarini, Mylan, Novartis, Purina, Sanofi-Aventis, Teva, Uriach, KYomed-Innov, MASK-air-SAS, outside submitted work. owns shares SAS KYomed-Innov. VK Norameda, BerlinCHemie DLL Allakos, Amstrong, Astrazeneca national global, Chiesi, DBV Technologies, Grunenthal, GSK Mylan/Viatris, MSD, Pfizer, Sanofi, Siegfried, UCB, Carnot, Abbvie, Lilly, Astrazeneca, Circassia, Purina institute, FR nonfinancial AstraZeneca, Medinfar, Azentis, SPAIC, LTB LETI, Vitoria Laboratories, TZ Henkel, Bayer, FAES, Astra Zeneca, AbbVie, Almirall, Astellas, Bencard, Berlin Chemie, Hal, Leti, Mesa, Merck, Stallergenes, Takeda, Kryolan, L'Oreal, work; Organizational affiliations: Commitee member: WHO-Initiative 'Allergic Its Asthma' (ARIA); Member Board: German Society Allergy Clinical Immunology (DGAKI); Head: European Centre Research Foundation (ECARF); President: Global Asthma Network (GA2LEN); Member: Committee Diagnosis Molecular Allergology, World Organization (WAO). COI disclose, Wienczyslawa Czarlewski, Anna Bedbrook, Tari Haahtela, Ludger Klimek, Oliver Pfaar, Piotr Kuna, Maciej Kupczyk, Boleslaw Samolinski, Arunas Valiulis, Rute Almeida, Cristina Jácome, Arzu Yorgancioglu, Karl-Christian Bergmann, Sinthia Bosnic-Anticevich, G Walter Canonica, Victoria Cardona, Lorenzo Cecchi, Claudia Chaves Loureiro, Alvaro Cruz, Bilun Gemicioglu, Wytske J Fokkens, Juan Carlos Ivancevich, Helga Kraxner, Daniel Laune, Renaud Louis, Michael Makris, Mario Morais-Almeida, Joaquim Mullol, Marek Niedoszytko, Yoshitaka Okamoto, Nikolaos Papadopoulos, Vincenzo Patella, Nhân Pham-Thi, Philip W Rouadi, Joaquin Sastre, Nicola Scichilone, Aziz Sheikh, Mikhail Sofiev, Sanna Toppila-Salmi, Ioanna Tsiligianni, Erkka Valovirta, Mihaela Zidarn, Rita Amaral, Ignacio Ansotegui, Louis-Philippe Boulet, Guy Brusselle, Roland Buhl, Denis Charpin, Philippe Devillier, Virginie Doyen, Ewa Jassem, Joos, Jutel, Thomas Keil, Kulus, Olga Lourenço, Ralph Mösges, Rachel Nadif, Stefania Nicola, Alberto Papi, Jean-Louis Pépin, Benoit Pétré, Francesca Puggioni, Santiago Quirce, Sietze Reitsma, Nicolas Roche, Monica Rodriguez-Gonzalez, Ana Sá-Sousa, Marine Savouré, Faradiba S Serpa, Milan Sova, Annette Sperl, y, Omar Usmani, Peter Valentin Tomazic, Olivier Vandenplas Data sharing applicable article new created analyzed study. Appendix S1. Please note: publisher content functionality any supporting supplied authors. Any queries (other missing content) should directed corresponding author article.

Language: Английский

Citations

6

Factors Affecting Usage of a Digital Asthma Monitoring Application by Old-Age Asthmatics Living in Inner Central Portugal DOI Creative Commons

Magda Abreu,

Adalberto Santos, Jorge Gama

et al.

Clinical Interventions in Aging, Journal Year: 2024, Volume and Issue: Volume 19, P. 971 - 979

Published: May 1, 2024

Purpose: To analyse factors affecting the ability to use digital asthma monitoring application Mask-Air ® in old-age individuals living inland Portugal. Patients and Methods: In this observational study, patients with medically confirmed who agreed participate were interviewed subdivided into Non-users Group: those could not Users could. Sociodemographic psychological data, comorbidities, status compared between groups. Assessment of reasons for refusal was based on a 6-item questionnaire. Results: Among 72 sequentially recruited (mean age ± SD 73.26± 5.43 yrs; 61 women; 11 men), 44 (61.1%; mean age±SD 74.64± 5.68 38 6 men)) included Group 28 (38.9%; 71.11± 4.26 23 5 men) Group. significantly older, had lower socioeconomic level, more frequently severe (25% vs 3.6%; Odds ratio=0.08 (95% CI=0.01– 0.81; p=0.033)) diabetes (32.6% 7.4%; ratio=0.17 CI=0.03– 0.80; p=0.025)) than The main using App "Lack required hardware" (n=35) "Digital illiteracy" (n=26), but lack interest among conditions it uncommon. Conclusion: Most asthmatics Beira Interior either smartphone or skills, which are significant obstacles implementing app-based studies. Plain Language Summary: This study done see whether possible mobile phone (App) help inner Central Portugal better monitor self-manage their disease. researchers group proven study. two subgroups: (44 patients) because they did have smartphone; (28 all App. helped download (called MASK-Air), given thorough explanation about it, how should be used daily basis symptoms. found that worse conditions, often diabetes. They also discovered knowing smartphone. These results show lacking tools frequent situations Portugal, these may own Keywords: asthma, mHealth, literacy, disease monitoring,

Language: Английский

Citations

1

Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis: A MASK‐air study DOI Creative Commons
Bernardo Sousa‐Pinto, Gilles Louis, Rafael José Vieira

et al.

Clinical and Translational Allergy, Journal Year: 2024, Volume and Issue: 14(6)

Published: May 28, 2024

Abstract Rationale It is unclear how each individual asthma symptom associated with diagnosis or control. Objectives To assess the performance of symptoms in identification patients and their association Methods In this cross‐sectional study, we assessed real‐world data using MASK‐air ® app. We compared frequency occurrence five (dyspnea, wheezing, chest tightness, fatigue night symptoms, as by Control Allergic Rhinitis Asthma Test [CARAT] questionnaire) probable, possible no current asthma. calculated sensitivity, specificity predictive values symptom, between control (measured e‐DASTHMA score). Results were validated a sample physician‐established Measurement Main included 951 (2153 CARAT assessments), 468 having probable asthma, 166 317 evidence Wheezing displayed highest (90.5%) positive value (90.8%). dyspnea tightness more strongly than other symptoms. Dyspnea was sensitivity (76.1%) one consistently e‐DASTHMA. Consistent results observed when assessing physician‐made Conclusions for diagnosis, while strongest

Language: Английский

Citations

1

Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air® DOI Creative Commons
Jean Bousquet, Bernardo Sousa‐Pinto, Josep M. Antó

et al.

Clinical and Translational Allergy, Journal Year: 2024, Volume and Issue: 14(9)

Published: Sept. 1, 2024

Language: Английский

Citations

1

The evolving reality of digital health DOI Creative Commons

Nana Bit-Avragim,

Jean Bousquet,

Stefano Cantù

et al.

Digital Health, Journal Year: 2024, Volume and Issue: 10

Published: Jan. 1, 2024

Myriad digital health interventions, applications, devices and technologies have, are, being developed to help refine personalise medicine from the patient, healthcare professional (HCP), system industry perspectives. At a gathering of leaders in health, discussion included current landscape such tools (DHTs), with specific examples cardiology respiratory medicine, both benefits sometime downfalls tools. While DHTs can patients HCPs detect monitor conditions, experts discussed how adoption may be hampered by issues as access technology; data privacy security concerns; technology integration into systems; cost reimbursement; lack guidelines regulatory hurdles. The suggested solutions issues, including wider availability ‘booths’ local patient; easy understand use phone applications; patient HCP incentives clear paths within system. These should aid shared decision-making and, ultimately, streamline for all.

Language: Английский

Citations

1