Cancer Statistics, 2021

CA A Cancer Journal for Clinicians, Journal Year: 2021, Volume and Issue: 71(1), P. 7 - 33

Published: Jan. 1, 2021

Each year, the American Cancer Society estimates numbers of new cancer cases and deaths in United States compiles most recent data on population-based occurrence. Incidence (through 2017) were collected by Surveillance, Epidemiology, End Results Program; National Program Registries; North Association Central Registries. Mortality 2018) Center for Health Statistics. In 2021, 1,898,160 608,570 are projected to occur States. After increasing 20th century, death rate has fallen continuously from its peak 1991 through 2018, a total decline 31%, because reductions smoking improvements early detection treatment. This translates 3.2 million fewer than would have occurred if rates had persisted. Long-term declines mortality 4 leading cancers halted prostate slowed breast colorectal cancers, but accelerated lung cancer, which accounted almost one-half 2014 2018. The pace annual doubled 3.1% during 2009 2013 5.5% 2018 men, 1.8% 4.4% women, 2.4% 5% overall. trend coincides with steady incidence (2.2%-2.3%) rapid gains survival specifically nonsmall cell (NSCLC). For example, NSCLC 2-year relative increased 34% persons diagnosed 2010 42% 2015 2016, including absolute increases 6% every stage diagnosis; small remained at 14% 15%. Improved treatment progress against drove record drop overall mortality, despite slowing momentum other common cancers.

Language: Английский

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Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2020, Volume and Issue: 18(4), P. 223 - 238

Published: Dec. 21, 2020

Language: Английский

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Endometrial Cancer

New England Journal of Medicine, Journal Year: 2020, Volume and Issue: 383(21), P. 2053 - 2064

Published: Nov. 18, 2020

Endometrial carcinoma is diagnosed in about 58,500 women the United States per year. It linked with obesity, excess estrogen, and Lynch syndrome. Oral contraceptives lower risk by 30 to 40%. Most patients undergo surgery or without radiation therapy.

Language: Английский

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Medical Care Costs Associated with Cancer Survivorship in the United States

Cancer Epidemiology Biomarkers & Prevention, Journal Year: 2020, Volume and Issue: 29(7), P. 1304 - 1312

Published: June 10, 2020

The prevalence of cancer survivorship is increasing. In this study, we provide contemporary population-based estimates and projections the overall site-specific cancer-attributable medical care costs in United States.We identified survivors aged ≥65 years diagnosed with between 2000 2012 from Surveillance, Epidemiology, End Results (SEER)-Medicare database used 2007 to 2013 claims estimate by site, phases care, stage at diagnosis. Annualized average for (Medicare Parts A B) oral prescription drugs Part D) were estimated subtracting patients matched controls. Costs are reported 2019 U.S. dollars. We combined phase-specific attributable national 2015 through 2030.Overall annualized highest end-of-life-cancer death phase, followed initial continuing (medical care: $105,500, $41,800, $5,300 drugs: $4,200, $1,800, $1,100, respectively). There was considerable variation site stage. Overall $183 billion projected increase 34% $246 2030, based only on population growth.Phase cost key inputs simulation models cost-effectiveness analyses.The cancer-attributed States substantial dramatically due changes alone, reflecting rising burden among survivors.

Language: Английский

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Prostate Cancer Incidence and Survival, by Stage and Race/Ethnicity — United States, 2001–2017

MMWR Morbidity and Mortality Weekly Report, Journal Year: 2020, Volume and Issue: 69(41), P. 1473 - 1480

Published: Oct. 15, 2020

Among U.S. men, prostate cancer is the second leading cause of cancer-related death (1). Past studies documented decreasing incidence overall since 2000 but increasing distant stage (i.e., signifying spread to parts body remote from primary tumor) starting in 2010 (2,3). described disparities survival by stage, age, and race/ethnicity using data covering ≤80% population (4,5). To provide recent on United States, CDC analyzed population-based registries that contribute Cancer Statistics (USCS).* 3.1 million new cases recorded during 2003-2017, localized, regional, distant, unknown accounted for 77%, 11%, 5%, 7% cases, respectively, significantly increased 2010-2017. During 2001-2016, 10-year relative localized was 100%. Overall, 5-year improved 28.7% 2001-2005 32.3% 2011-2016; period highest among Asian/Pacific Islanders (API) (42.0%), followed Hispanics (37.2%), American Indian/Alaska Natives (AI/AN) (32.2%), Black men (31.6%), White (29.1%). Understanding differences race/ethnicity, age can guide public health planning related screening, treatment, survivor care. Future research into could inform interventions aimed at improving outcomes.

Language: Английский

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Annual Report to the Nation on the Status of Cancer, Part 1: National Cancer Statistics

JNCI Journal of the National Cancer Institute, Journal Year: 2021, Volume and Issue: 113(12), P. 1648 - 1669

Published: June 28, 2021

The American Cancer Society, Centers for Disease Control and Prevention, National Institute, North Association of Central Registries collaborate to provide annual updates on cancer incidence mortality trends by type, sex, age group, racial/ethnic group in the United States. In this report, we also examine stage-specific survival melanoma skin (melanoma).Incidence data all cancers from 2001 through 2017 cases diagnosed during 2001-2014 followed-up 2016 were obtained Prevention- Institute-funded population-based registry programs compiled Registries. Data deaths 2018 Center Health Statistics' Vital Statistics System. Trends age-standardized death rates 2-year relative estimated joinpoint analysis, expressed as average percent change (AAPC) most recent 5 years (2013-2017 2014-2018 mortality).Overall (per 100 000 population) ages 2013-2017 487.4 among males 422.4 females. During period, remained stable but slightly increased females (AAPC = 0.2%, 95% confidence interval [CI] 0.1% 0.2%). Overall 185.5 133.5 overall decreased both -2.2%, CI -2.5% -1.9%) -1.7%, -2.1% -1.4%); 11 19 common 14 20 females, each sex. 2014-2018, declines accelerated lung melanoma, slowed down colorectal female breast cancers, leveled off prostate cancer. Among children younger than 15 adolescents young adults aged 15-39 years, continued decrease contrast increasing rates. Two-year distant-stage was those 2001-2009 3.1% (95% 2.8% 3.5%) per year 2009-2014, with comparable females.Cancer States continue decline many types, melanoma. For several other major however, increase or previous have ceased. Moreover, children, adults. These findings inform efforts related prevention, early detection, treatment broad equitable implementation effective interventions, especially under resourced populations.

Language: Английский

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Endometrial cancer

Nature Reviews Disease Primers, Journal Year: 2021, Volume and Issue: 7(1)

Published: Dec. 9, 2021

Language: Английский

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Projected estimates of cancer in Canada in 2020

Canadian Medical Association Journal, Journal Year: 2020, Volume and Issue: 192(9), P. E199 - E205

Published: March 2, 2020

BACKGROUND:

Cancer projections to the current year help in policy development, planning of programs and allocation resources. We sought provide an overview expected incidence mortality cancer Canada 2020 follow-up Canadian Statistics 2019 report.

METHODS:

obtained data from National Incidence Reporting System (1984–1991) Canadian Registry (1992–2015). Mortality (1984–2015) were Vital — Death Database. All databases are maintained by Canada. counts age-standardized rates projected for 23 types sex geographic region (provinces territories) all ages combined.

RESULTS:

An estimated 225 800 new cases 83 300 deaths 2020. The most commonly diagnosed cancers be lung overall (29 800), breast females (27 400) prostate males (23 300). Lung is also leading cause death, accounting 25.5% deaths, followed colorectal (11.6%), pancreatic (6.4%) (6.1%) cancers. will generally higher eastern provinces than western provinces.

INTERPRETATION:

number remains high and, owing growing aging population, continue increase. Although progress has been made reducing major (breast, lung), there limited cancer, which third death Additional efforts improve uptake existing programs, as well advance research, prevention, screening treatment, needed address burden

Language: Английский

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Recent Advances in the Treatment of Melanoma

New England Journal of Medicine, Journal Year: 2021, Volume and Issue: 384(23), P. 2229 - 2240

Published: June 9, 2021

The incidence of melanoma has increased, but mortality declined with improved management. Sentinel-node sampling reduced morbidity associated staging surgery, and treatment advanced disease the use targeted therapy checkpoint immunotherapy.

Language: Английский

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Epidemiology and risk-stratification of NAFLD-associated HCC

Journal of Hepatology, Journal Year: 2021, Volume and Issue: 75(6), P. 1476 - 1484

Published: Aug. 25, 2021

Language: Английский

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