A scoping review of mechanisms of auricular acupuncture for treatment of pain

Postgraduate Medicine, Journal Year: 2024, Volume and Issue: 136(3), P. 255 - 265

Published: March 19, 2024

Auricular acupuncture (AA) is becoming increasingly common in primary care clinics, emergency departments and peri-operatively for pain relief. Over the last decade, since comprehensive reviews were published, literature has expanded. In this scoping review, we seek to document efficacy of AA treating both acute chronic pain, describe mechanism action discuss how been integrated into Western medicine date.

Language: Английский

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Relation extraction using large language models: a case study on acupuncture point locations

Journal of the American Medical Informatics Association, Journal Year: 2024, Volume and Issue: 31(11), P. 2622 - 2631

Published: Aug. 29, 2024

Abstract Objective In acupuncture therapy, the accurate location of acupoints is essential for its effectiveness. The advanced language understanding capabilities large models (LLMs) like Generative Pre-trained Transformers (GPTs) and Llama present a significant opportunity extracting relations related to acupoint locations from textual knowledge sources. This study aims explore performance LLMs in acupoint-related assess impact fine-tuning on GPT’s performance. Materials Methods We utilized World Health Organization Standard Acupuncture Point Locations Western Pacific Region (WHO Standard) as our corpus, which consists descriptions 361 acupoints. Five types (“direction_of”, “distance_of”, “part_of”, “near_acupoint”, “located_near”) (n = 3174) between were annotated. Four compared: pre-trained GPT-3.5, fine-tuned GPT-4, well pretrained 3. Performance metrics included micro-average exact match precision, recall, F1 scores. Results Our results demonstrate that GPT-3.5 consistently outperformed other scores across all relation types. Overall, it achieved highest score 0.92. Discussion superior model, shown by scores, underscores importance domain-specific enhancing extraction acupuncture-related tasks. light findings this study, offers valuable insights into leveraging developing clinical decision support creating educational modules acupuncture. Conclusion effectiveness GPT locations, with implications accurately modeling promoting standard implementation training practice. also contribute advancing informatics applications traditional complementary medicine, showcasing potential natural processing.

Language: Английский

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Efficacy of electroacupuncture in the treatment of insomnia in cancer patients: A meta-analysis

Medicine, Journal Year: 2025, Volume and Issue: 104(1), P. e41123 - e41123

Published: Jan. 3, 2025

The purpose of this meta-analysis current studies was to assess the efficacy electroacupuncture for cancer-related insomnia. A comprehensive search conducted encompassing randomized controlled trials examining in treating insomnia across CNKI, VIP, Wang Fang, PubMed, Embase, Cochrane library, and Web Science, with a deadline December 26, 2023. manual's risk-of-bias evaluation used quality assessment, while Stata 15.0 data analysis. Eight involving 537 individuals were finally included. Meta-analysis results suggested that improved total sleep time [SMD = 0.68, 95% CI (0.31, 1.06)], efficiency 1.26, (0.02, 2.50)], reduced Pittsburgh index -0.44, (-0.63, -0.25)], severity -1.23, (-1.88, -0.58)], onset latency -0.76, (-1.36, -0.15)] cancer patients. Based on study, we found may have better effect

Language: Английский

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Chronic pain is a risk factor for all-cause and cancer-specific mortality in cancer survivors: a population-based cohort study

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 25, 2025

Evidence is lacking on whether chronic pain related to the risk of cancer mortality. This study seeks unveil association between and all-cause, cancer, as well non-cancer death in patients based National Health Nutrition Examination Survey (NHANES) database. Cancer survivors aged at least 20 (n = 1369) from 3 NHANES (1999–2004) cycles were encompassed. Chronic determined through self-report. We employed records Death Index for determination status reason. All-cause, deaths primary outcomes. used time-dependent ROC curve assessment evaluate predictive value patients. Over a median 141-month follow-up (interquartile range: 61–201 months), 884 (64.57%) 1,369 sufferers died, which 259 (18.91%) died 625 (45.65%) other causes. Compared with non-chronic survivors, correlated elevated all-cause mortality (Hazard Ratio (HR), 1.40; 95% CI, 1.14–1.72, p 0.001) (HR, 1.75; 1.16–2.64, 0.008), primarily lasting months or more. was higher 1.38; 1.04–1.82, 0.025), no significant results found duration. Time-dependent curves showed area under (AUC) 1, 3, 5, 10, 20-year survival 0.71, 0.78, 0.84, 0.89, 0.96, respectively. The AUCs 0.83, 0.87, 0.91, 0.94, 0.95, respectively, those 0.82, 0.86, 0.90, 0.97, associated heightened population. Clinical staff should focus this patient

Language: Английский

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Efficacy of electroacupuncture for insomnia in cancer patients: a systematic review and meta-analysis

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 10, 2025

Background Insomnia is a prevalent symptom among cancer patients. Electroacupuncture (EA) has been widely applied in managing sleep disorders, particularly patients or those experiencing insomnia. Objectives This meta-analysis aims to evaluate the efficacy and safety of electroacupuncture for treating cancer-related Methods Two independent reviewers conducted comprehensive searches across multiple databases, including EMBASE, Web Science, PubMed, Cochrane Library, Wanfang Digital Journals, China National Knowledge Infrastructure (CNKI), VIP Database Chinese Technical Periodicals. The search was completed on April 28, 2024. independently performed literature screening, data extraction, risk bias (ROB) assessment using revised ROB tool. Data were analyzed RevMan 5.4 Stata 15.0 software. Results Eight randomized controlled trials (RCTs) involving 550 (305 experimental group 245 control group) included. EA significantly reduced Pittsburgh Sleep Quality Index (PSQI) scores (SMD = −0.86, 95% CI [−1.24, −0.49], p < 0.001), Severity (ISI) −1.14, [−1.59, −0.69], latency (SL) −0.48, [−0.73, −0.23], disturbance (SDB) −0.44, −0.16], 0.002). also lowered Hospital Anxiety Depression Scale-Anxiety (HADS-Anxiety) −0.59, [−0.91, −0.26], 0.001) Scale-Depression (HADS-Depression) −0.73, [−1.06, −0.40], while increasing total time (TST) 0.65, [0.14, 1.17], 0.013). No significant differences observed Athens Scale (AIS), duration (SD), efficiency (SE), quality (SQ) between groups. Conclusion shown promising potential insomnia by reducing disturbances. However, additional high-quality studies are necessary validate these findings. Systematic review registration https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=567567 , Identifier CRD42024567567.

Language: Английский

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Personalized Medicine in Cancer Pain Management

Journal of Personalized Medicine, Journal Year: 2023, Volume and Issue: 13(8), P. 1201 - 1201

Published: July 28, 2023

Background: Previous studies have documented pain as an important concern for quality of life (QoL) and one the most challenging manifestations cancer patients. Thus, management (CPM) plays a key role in treating related to cancer. The aim this systematic review was investigate CPM, with emphasis on personalized medicine, introduce new pharmacogenomics-based procedures detecting Methods: This study systematically reviewed PubMed from 1990 2023 using keywords such cancer, pain, medicine. A total 597 publications were found, after multiple filtering processes, 75 papers included. In silico analyses performed GeneCards, STRING-MODEL, miRTargetLink2, PharmGKB databases. Results: results reveal that recent reports mainly focused medicine strategies data are rapidly being introduced. literature highly relevant publications, combined bioinformatics results, identified list 57 evidence-based genes primary gene further approaches. frequently mentioned CYP2D6, COMT, OPRM1. Moreover, among 127 variants through both mining database, 21 remain potential candidates whole-exome sequencing (WES) analysis. Interestingly, hsa-miR-34a-5p hsa-miR-146a-5p suggested putative circulating biomarkers prognosis diagnosis. Conclusions: conclusion, highlights promising strategy utilizing approaches alleviate pain.

Language: Английский

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Racial differences in treatment adherence and response to acupuncture and cognitive behavioral therapy for insomnia among Black and White cancer survivors

Cancer Medicine, Journal Year: 2024, Volume and Issue: 13(16)

Published: Aug. 1, 2024

Racial disparities in sleep are well-documented. However, evidence-based options for addressing these lacking cancer populations. To inform future research on interventions, this study aims to understand racial differences treatment responses acupuncture and cognitive behavioral therapy insomnia (CBT-I) among Black White survivors.

Language: Английский

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Efficacy of non-pharmacological interventions on sleep quality in patients with cancer-related insomnia: a network meta-analysis

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 20, 2024

Objective Despite the widespread application of non-pharmacological therapies in treating cancer-related insomnia, a comprehensive assessment these methods is lacking. This study aims to compare efficacy 11 interventions for providing theoretical basis clinicians choosing treatment methods. Methods We searched five databases, including Cochrane Central Register Controlled Trials, PubMed, Embase, Wiley Library, and Web Science, relevant randomized controlled trials. Included studies involved patients diagnosed with employed treatments, reported outcomes using PSQI ISI. Bayesian statistical were used network meta-analysis, processing was performed Review Manager 5.4 Stata 14.0 software. The results thoroughly analyzed evaluated, publication bias assessed funnel plot tests. Results Our included 41 trials, comprising different (3,541 participants), analysis identifying Electroacupuncture as most effective, SUCRA value 92.2% ISI, this followed by Professionally administered Cognitive behavioral therapy insomnia(PCBT-I) Mindfulness-based cognitive therapy(MBCT), values 78.4 64.1%, respectively. Traditional insomnia(CBT-I) VCBT-I showed lower 55.9 55.2%, Exercise control groups had lowest efficacy, 24.0 16.1%. Using outcome measure, Massage ranked highest improving sleep quality 92.2%, insomnia (PCBT-I) Electroacupuncture. League tables indicated significant improvements MT compared groups, (EA) showing an MD −7.80 (95% CI: −14.45, −1.15) −4.23 (CI: −8.00, −0.46). Conclusion Considering both indicators, significantly effective alleviating severity while quality. Therefore, May be particularly choices. Future research should further explore specific mechanisms action their patient groups.

Language: Английский

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Integrative Approaches for Cancer Pain Management

Current Oncology Reports, Journal Year: 2024, Volume and Issue: 26(6), P. 691 - 705

Published: April 29, 2024

Language: Английский

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Mechanism and application of acupuncture and electro‐acupuncture associated with cancer therapy

MedComm – Oncology, Journal Year: 2024, Volume and Issue: 3(2)

Published: May 19, 2024

Abstract The rapid progress in cancer treatment, along with the increase cure and control rates, has led to gradual acceptance of as a chronic disease. Cancer treatment is comprehensive long‐term. However, symptoms side effects can hinder patients' quality life adherence ultimately impacrefting their long‐term survival. Acupuncture (AC) electro‐acupuncture (EA) have been widely used treat various diseases. AC EA demonstrated ability relieve related treatment. review provides brief overview historical lineage basic principles well detailed exploration mechanisms clinical applications effects. play therapeutic role by regulating systems nervous, endocrine, immune so on. Clinical studies that effectively pain, postoperative ileus, other symptoms. safety tested worldwide. Furthermore, we discuss challenges future research directions for field

Language: Английский

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