Advancements in Digital Cytopathology Since COVID-19: Insights from a Narrative Review of Review Articles
Healthcare,
Journal Year:
2025,
Volume and Issue:
13(6), P. 657 - 657
Published: March 17, 2025
Background/Objectives:
The
integration
of
digitalization
in
cytopathology
is
an
emerging
field
with
transformative
potential,
aiming
to
enhance
diagnostic
precision
and
operational
efficiency.
This
narrative
review
reviews
(NRR)
seeks
identify
prevailing
themes,
opportunities,
challenges,
recommendations
related
the
process
cytopathology.
Methods:
Utilizing
a
standardized
checklist
quality
control
procedures,
this
examines
recent
advancements
future
implications
domain.
Twenty-one
studies
were
selected
through
systematic
process.
Results:
results
highlight
key
trends,
digital
First,
study
identifies
pivotal
themes
that
reflect
ongoing
technological
transformation,
guiding
focus
areas
field.
A
major
trend
artificial
intelligence
(AI),
which
increasingly
critical
improving
accuracy,
streamlining
workflows,
assisting
decision
making.
Notably,
AI
technologies
like
large
language
models
(LLMs)
chatbots
are
expected
provide
real-time
support
automate
tasks,
though
concerns
around
ethics
privacy
must
be
addressed.
also
emphasize
need
for
protocols,
comprehensive
training,
rigorous
validation
ensure
tools
reliable
effective
across
clinical
settings.
Lastly,
holds
significant
potential
improve
healthcare
accessibility,
especially
remote
areas,
by
enabling
faster,
more
efficient
diagnoses
fostering
global
collaboration
telepathology.
Conclusions:
Overall,
highlights
impact
cytopathology,
efficiency,
accessibility
whole-slide
imaging
While
plays
role,
broader
on
integrating
solutions
workflows
collaboration.
Addressing
challenges
such
as
standardization,
ethical
considerations
crucial
fully
realize
these
advancements.
Language: Английский
Double–Multiplex Immunostainings for Immune Profiling of Invasive Breast Carcinoma: Emerging Novel Immune-Based Biomarkers
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(7), P. 2838 - 2838
Published: March 21, 2025
The
role
of
tumor
microenvironment
in
invasive
breast
cancer
prognosis
and
treatment
is
highly
appreciated.
With
the
advent
immunotherapy,
immunophenotypic
characterization
primary
tumors
gaining
attention
as
it
can
improve
patient
stratification.
Here,
we
discuss
benefits
spatial
analysis
employing
double
multiplex
immunostaining,
allowing
simultaneous
detection
more
than
one
protein
on
same
tissue
section,
which
turn
helps
us
provide
functional
insight
into
infiltrating
immune
cells
within
tumors.
We
focus
studies
demonstrating
prognostic
predictive
impact
distinct
tumor-infiltrating
lymphocyte
subpopulations
including
different
CD8(+)
T
subsets
well
CD4(+)
tumor-associated
macrophages
carcinoma.
clinical
value
cell
topography
also
further
refer
to
how
integration
digital
pathology
artificial
intelligence
routine
practice
could
enhance
accuracy
immunostainings
evaluation
microenvironment,
maximizing
our
perception
host
response
improvement
turning
decision-making
towards
precise
immune-associated
therapies.
Language: Английский