New Strategy for Enhancing Energetic Properties by Regulating Trifuroxan Configuration: 3,4-Bis(3-nitrofuroxan-4-yl)furoxan

Scientific Reports, Journal Year: 2019, Volume and Issue: 9(1)

Published: March 13, 2019

It is of current development to construct high-performance energetic compounds by aggregation groups with dense arrangement. In this study, a hydrogen-free high-density 3,4-bis(3-nitrofuroxan-4-yl)furoxan (BNTFO-I) was designed and synthesized in simple, straightforward manner. Its isomer, 3,4-bis(4-nitrofuroxan-3-yl)furoxan (BNTFO-IV), also obtained isomerization. The structures BNTFO-I BNTFO-IV were confirmed single-crystal X-ray analysis for the first time. Surprisingly, has remarkable calculated crystal density 1983 g cm-3 at 296 K, which distinctly higher than (1.936 cm-3, K), ranks highest among azole-based CNO yet reported. noteworthy that exhibits excellent detonation properties (vD, 9867 m s-1, P, 45.0 GPa). interesting configuration differences provide insight into design new advanced materials.

Language: Английский

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Exploring the highly dense energetic materials via regiochemical modulation: A comparative study of two fluorodinitromethyl-functionalized herringbone trifuroxans

Chemical Engineering Journal, Journal Year: 2019, Volume and Issue: 391, P. 123573 - 123573

Published: Nov. 25, 2019

Language: Английский

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Recent Advances in the Synthesis and Biomedical Applications of Heterocyclic NO-Donors

Molecules, Journal Year: 2021, Volume and Issue: 26(18), P. 5705 - 5705

Published: Sept. 21, 2021

Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide number vascular diseases well immune neurodegenerative disorders were found to be directly associated with disruption NO production living organisms. These issues justify constant search novel NO-donors improved pharmacokinetic profiles prolonged action. In series known structural classes capable release, heterocyclic are special importance due their increased hydrolytic stability low toxicity. It no wonder synthetic biochemical investigations have emerged significantly recent years. this review, we summarized advances the synthesis, reactivity biomedical applications promising (furoxans, sydnone imines, pyridazine dioxides, azasydnones). The potential each system along mechanisms action emphasized.

Language: Английский

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Simple and energetic: Novel combination of furoxan and 1,2,4-triazole rings in the synthesis of energetic materials

Energetic Materials Frontiers, Journal Year: 2022, Volume and Issue: 3(3), P. 146 - 153

Published: Aug. 17, 2022

Two novel representatives of energetic (1,2,4-triazolyl)furoxans were prepared from the readily available (furoxanyl)amidrazones. Synthesized compounds thoroughly characterized with IR and multinuclear NMR spectroscopy, elemental analysis X-ray diffraction data. Analysis structural features supported by quantum-chemical calculations revealed main reasons for experimentally observed difference in thermal stability mechanical sensitivity both compounds. It was found that 3-cyano-4-(1H-1,2,4-triazol-3-yl)furoxan is more thermally stable (Td: 229 ​°C) than 4-azido-3-(1H-1,2,4-triazol-3-yl)furoxan 154 latter compound also sensitive to impact friction. In addition, heterocyclic assemblies have high detonation parameters (vD: 7.0–8.0 ​km·s−1; p: 22–29 ​GPa) exceeding those benchmark explosives trinitrotoluene hexanitrostilbene which enable their usability various applications.

Language: Английский

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Novel energetic oxadiazole assemblies

Mendeleev Communications, Journal Year: 2022, Volume and Issue: 32(1), P. 111 - 113

Published: Jan. 1, 2022

Language: Английский

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