Diphenylbutadiene Fluorescent Analogues in Sub‐cellular Imaging and Monitoring Mitophagy.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: 19(21)

Published: July 25, 2024

A series of donor-acceptor (D-π-A) substituted diphenylbutadienes exhibiting solvatochromic emission and a large Stokes shift (100-200 nm) were designed synthesized for distinctive organelle labelling, enabling real-time monitoring behaviour such as lysosomal dynamics, mitophagy monitoring, stress responses. The morpholine-substituted D-A-D diphenylbutadiene (M2) was employed to investigate selective imaging lysosomes, the uptake damaged mitochondria through mitophagy, viscosity or pH changes. Other derivatives (M1, M3, M4) selectively accumulated in lipid droplets. All demonstrated significant 5-day post-fertilization zebrafish larvae, with M2 showing maximum enterocyte-containing heart intestinal regions, which include lysosomes.

Language: Английский

---

Individual and simultaneous encapsulation and delivery of incompatible dyes in biocompatible multicompartment terpolymer micelles

European Polymer Journal, Journal Year: 2024, Volume and Issue: 218, P. 113344 - 113344

Published: July 26, 2024

Language: Английский

---

The Synthesis of a Large Stokes-Shift Dye and Intercalation into the Nanochannels of Zeolite L

Materials, Journal Year: 2024, Volume and Issue: 17(22), P. 5669 - 5669

Published: Nov. 20, 2024

A host-guest-based fluorescent composite with a large Stokes shift was synthesized by intercalating 2,2'-(thiophene-2,5-diyl)bis(benzo[d]oxazol-6-amine) (BBTA) into the nanochannels of zeolite L (ZL) and sealing pores (3-aminopropyl)triethoxysilane (APTES). To confirm orientation amino groups in BBTA, single crystal 2,5-bis(6-nitrobenzo[d]oxazol-2-yl)thiophene (BBTN) grown examined X-ray crystallography. The evidence successful intercalation BBTA ZL provided fluorescence spectrometry, gas sorption microscopy. showed 6641 cm

Language: Английский

---

Macrocyclic Bridgehead Fluorophores, Pyrrolyl-diazabicyclo[8.3.1]tetradecadienones, with Giant Stokes Shifts

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 26, 2024

A previously unknown class of fluorophores was discovered, which represents 14-membered bridgehead heterocycles, pyrrolyl-diazabicyclo[8.3.1]tetradecadienones, herein referred to as PY-14-ONEs. The new are characterized by giant Stokes shifts ∼8000-10,250 cm

Language: Английский

---

A Furo-Fused Coumarin Dye with Large Stokes Shift and Intensive Emission Intensity: Its Design,Synthesis, Characterizaiton, Optical Properties and Solvatochromic Applications

Published: Jan. 1, 2024

Language: Английский

---

Non-doped, solid-state red-emitting phenothiazine-pyrene chalcones: Synthesis, aggregation-induced emission enhancement and mechanofluorochromism

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 116222 - 116222

Published: Dec. 1, 2024

Language: Английский

---