Impact of Fluoride on Thyroid Function and Histopathology in Cyprinus carpio: Implications for Aquatic Ecosystems

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101964 - 101964

Published: Feb. 20, 2025

Fluoride pollution in freshwater bodies is becoming alarming because it interferes with the endocrine system of water-dwelling organisms. In this study, we evaluated effects sublethal fluoride levels on thyroid hormone and histological alterations Cyprinus carpio, a popular model fish species used ecotoxicity experiments. The low, medium, high groups received 1, 5, 10 mg/L fluoride, respectively, thyroxine plasma (T4) triiodothyronine (T3) were assessed at 7, 14, 21, 35 days. findings revealed that both T4 T3 significantly decreased increasing dose ranged from to 10-41 % lower than controls group. On day 35, reduced by 42 50 exposure group compared those control Changes gland observed under light microscope included, but not limited to, small follicle size, epithelial hypertrophy, hyperplasia, especially high-fluoride These results suggest elevated causes hormonal imbalance carpio affecting biosynthesis functionality, which may result growth reproductive failure. eminent dose-response data concentration degree disruption clearly emphasise severe endocrine-disruptive increased concentrations. present study agree other studies have described inhibitory effect function different species. Therefore, conclude be potent disruptor environment. As hormones play significant roles metabolic physiological functions fish, these underscore importance improving standards habitats. Research molecular pathways lead dysfunction when exposed chemical substance

Language: Английский

Microgeographic variation in demography and thermal regimes stabilize regional abundance of a widespread freshwater fish

Ecological Applications, Journal Year: 2023, Volume and Issue: 34(2)

Published: Dec. 10, 2023

Abstract Predicting the persistence of species under climate change is an increasingly important objective in ecological research and management. However, biotic abiotic heterogeneity can drive asynchrony population responses at small spatial scales, complicating species‐level assessments. For widely distributed consisting many fragmented populations, such as brook trout ( Salvelinus fontinalis ), understanding drivers dynamics improve predictions range‐wide impacts. We analyzed demographic time series from mark–recapture surveys 11 natural populations eastern Canada over 13 years to examine extent, drivers, consequences fine‐scale variation. The focal were genetically differentiated, occupied a area (~25 km 2 ) with few human impacts, experienced similar conditions. Recruitment was highly asynchronous, weakly related variables showed population‐specific relationships other processes, generating diverse dynamics. In contrast, individual growth mostly synchronized among driven by shared positive relationship stream temperature. Outputs models unrelated four five hypothesized (recruitment, growth, reproductive success, phylogenetic distance), but variation groundwater inputs strongly influenced temperature regimes stock–recruitment relationships. Finally, generated portfolio effect that stabilized regional abundance. Our results demonstrated demographics habitat diversity microgeographic scales play significant role moderating change. Moreover, we suggest absence activities within study streams preserved contributed abundance, while eased monitoring increased likelihood detecting asynchrony. Therefore, anthropogenic degradation, landscape context, scale must be considered when developing management strategies monitor maintain are diverse, stable, resilient

Language: Английский