Serial direct sodium removal in patients with heart failure and diuretic resistance

European Journal of Heart Failure, Journal Year: 2024, Volume and Issue: 26(5), P. 1215 - 1230

Published: March 31, 2024

Language: Английский

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Konsensuspapier zum Management kardiovaskulärer Erkrankungen bei chronischer Nierenkrankheit

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Die chronische Nierenkrankheit (CKD) ist einer der wichtigsten Risikofaktoren für Herz-Kreislauf-Erkrankungen (CVD; manifestiert durch koronare Herzkrankheit, Herzinsuffizienz, Arrhythmien und plötzlichen Herztod), das gleichzeitige Vorliegen sowohl von CVD CKD hat einen erheblichen Einfluss auf die Prognose Patienten. diagnostischen therapeutischen Möglichkeiten kardiovaskulärer Erkrankungen sind bei fortgeschrittener häufig eingeschränkt, viele interventionelle medikamentöse Therapien besteht wenig oder keine Evidenz aus großen klinischen Studien. Das vorliegende Konsensuspapier gibt Überblick über Besonderheiten fasst aktuelle Empfehlungen zur Therapie Patienten mit zusammen.

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Counteracting the Mechanisms of Heart Failure is the Most Effective Way to Decongest Patients while Improving Outcomes

Cardiac failure review, Journal Year: 2025, Volume and Issue: 11

Published: Feb. 4, 2025

Diuretic therapy is not associated with improved outcomes in heart failure and may cause significant side effects. Counteracting the core pathophysiological mechanisms of through neurohormonal blockade while reducing reliance on diuretics potentially most effective method decongestion.

Language: Английский

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Long-term trajectory of estimated glomerular filtration rate in ambulatory patients with type 2 diabetes and heart failure: clinical insights and prognostic implications

Cardiovascular Diabetology, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 5, 2025

Although previous studies have evaluated renal function decline in patients with heart failure (HF), there is limited evidence on long-term trajectories, especially concomitant HF and type 2 diabetes (T2D). This study aims to provide a detailed analysis of over an extended follow-up period well-characterized cohort T2D. post hoc subanalysis prospective registry involving ambulatory T2D referred specialized clinic. The estimated glomerular filtration rate (eGFR) was assessed at baseline during scheduled visits every three months using the Chronic Kidney Disease Epidemiology Collaboration formula. Loess curves were plotted for predefined subgroups, multivariable longitudinal Cox regression analyses performed evaluate associations between eGFR trajectories all-cause mortality. A total 1,114 included, mean age 69.3 ± 10.3 years, 68.2% men. In total, 10,830 creatinine measurements analysed, 15.8 9.4 per patient. significant progressive observed, average annual - 2.05 (95% CI 2.11 1.95, p < 0.001) ml/min/1.73 m2. Subgroup indicated that older age, nonischaemic aetiology, HFpEF or HFmrEF, poor glycaemic control, higher eGFRs associated more pronounced function. Furthermore, decrease independently increased risk offers novel insights into identifies key clinical factors accelerated decline. Future research warranted validate these results larger, diverse cohorts explore potential therapeutic interventions.

Language: Английский

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Nonatherosclerotic Cardiovascular Disease in Chronic Kidney Disease

Cardiology Clinics, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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