An
effective
and
simple
visible
light-induced
heterogeneous
g-C3N4-catalyzed
decarboxylative
reaction
of
quinoxalin-2(1H)-ones
with
N-aryl
glycines
was
developed.
When
the
performed
in
DMSO/H2O
EtOH,
products
dihydroquinoxalin-2(1H)-ones
tetrahydroimidazo[1,5-a]quinoxalin-4(5H)-ones
were
unprecedentedly
obtained
good
yields,
respectively.
This
solvent-dependent
system
offers
advantages,
including
easy
operation,
short
time,
high
chemoselectivity,
a
recyclable
catalyst,
metal-/base-/oxidant-free,
mild
conditions.
Organic Letters,
Journal Year:
2021,
Volume and Issue:
23(8), P. 2976 - 2980
Published: March 29, 2021
A
general
and
metal-free
visible-light-induced
decarboxylative
arylation
procedure
at
room
temperature
was
described
for
the
construction
of
acylated
heterocyclic
derivatives,
such
as
benzimidazo/indolo[2,1-a]isoquinolin-6(5H)-ones,
aroylazaspiro[4.5]trienones,
thioflavones,
so
on.
This
practical
conducted
by
using
2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile
(4CzIPN)
a
photocatalyst
under
mild
conditions,
which
avoided
use
an
additional
base,
traditional
heating,
metal
reagents.
Organic Chemistry Frontiers,
Journal Year:
2020,
Volume and Issue:
8(3), P. 445 - 465
Published: Oct. 26, 2020
The
application
of
the
cyano
group
as
a
radical
acceptor
in
cascade
reactions
for
construction
various
important
heterocycles
and
carbocycles
was
summarized.
ChemistrySelect,
Journal Year:
2020,
Volume and Issue:
5(42), P. 13103 - 13134
Published: Nov. 13, 2020
Abstract
Sodium
sulfinates,
sulfinic
acids,
sulfonyl
chlorides
and
hydrazides
as
readily
available
efficient
sulfonylation
reagents
have
been
extensively
explored
in
recent
years.
Sulfonyl
radical
can
be
generated
from
these
via
different
methods,
then
the
could
react
with
various
substrates
pathways
to
afford
corresponding
products.
In
this
review,
we
will
summarize
progress
reaction
using
sodium
three
terms
of
reagents,
classify
reactions
into
four
types:
1.
Sulfonylation
sulfinates.
2.
acid.
3.
chlorides.
4.
hydrazides.
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(13), P. 2609 - 2614
Published: May 1, 2020
Abstract
With
ethylene
glycol
as
a
green
solvent,
general
transition
metal‐free
photocatalytic
system
using
9‐mesityl‐10‐methylacridinium
perchlorate
(Acr
+
−Mes
⋅
ClO
4
−
)
catalyst
was
developed
for
the
synthesis
of
sulfone‐containing
heterocycles
including
thioflavones,
oxindoles,
and
quinoline‐2,4(1
H
,3
)‐diones
through
cascade
sulfonation/cyclization
reactions
under
irradiation
blue
light
at
room
temperature.
magnified
image
Organic Chemistry Frontiers,
Journal Year:
2020,
Volume and Issue:
7(9), P. 1107 - 1112
Published: Jan. 1, 2020
The
synthesis
of
C2-nitrogenated
chromones
has
been
performed
via
reactions
enaminones
and
nitrogen
nucleophiles
based
on
an
unconventional
β-C–H
bond
functionalization
a
featured
chromone
annulation
enaminones.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(15), P. 2657 - 2662
Published: April 11, 2023
An
N-heterocyclic
carbene
(NHC)-catalyzed
facile
assembly
of
α-sulfonyl
ketones
has
been
successfully
developed
through
a
radical-mediated
sulfonyl
methylation
readily
available
aldehydes.
This
protocol
involves
the
effective
single-electron
transfer
reduction
α-iodosulfones
by
NHC-bound
Breslow
intermediates,
thus
allowing
subsequent
radical-radical
coupling
to
afford
target
compounds.
Moreover,
catalytic
system
was
found
be
equally
for
difunctionalization
styrenes
and
1,3-enynes
via
three-component
radical
relay
process.
European Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
26(48)
Published: Oct. 11, 2023
Abstract
N
‐Heterocyclic
carbene
(NHC)
catalyzed
radical‐radical
reactions
have
been
proven
to
be
powerful
strategies
for
assembling
ketyl‐containing
compounds
via
single
electron
transfer
(SET)
pathway
under
either
thermal
conditions
or
photoredox
conditions.
In
this
context,
acylation
of
alkenes
radical
relay
NHC‐organocatalysis
has
also
opened
a
new
window
the
difunctionalization
construct
valuable
molecules
in
organic
synthesis.
review,
advances
and
progress
were
summarized
according
different
ways
generation
key
NHC‐bound
ketyl‐type
radicals.
Furthermore,
reaction
scopes,
limitations
mechanisms
discussed
based
on
types
catalytic
systems.
Conclusions
perspectives
put
forward
at
end.
