Efficient enantioselective synthesis of CF2H-containing dispiro[benzo[b]thiophene-oxindole-pyrrolidine]s via organocatalytic cycloaddition DOI

Yabo Deng,

Yongzhen Li,

Yalan Wang

et al.

Organic Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 9(1), P. 210 - 215

Published: Nov. 24, 2021

A novel kind of CF 2 H-containing dispiro[benzo[ b ]thiophene-oxindole-pyrrolidine] has been achieved via an organocatalyzed 1,3-dipole reaction.

Language: Английский

Organocatalytic Asymmetric [4 + 2]-Cycloadditions of 2-Aminophenyl Enones with Isatin-Derived Ketimines: Diastereo- and Enantioselective Synthesis of Spirooxindole-Tetrahydroquinazolines DOI
Ji Won Han, Yoseop Kim, Sung‐Gon Kim

et al.

Organic Letters, Journal Year: 2023, Volume and Issue: 26(1), P. 252 - 257

Published: Dec. 26, 2023

A novel method for the enantioselective synthesis of spiro

Language: Английский

Citations

6
Organocatalysis in 1,3-Dipolar Cycloaddition Reactions (A Review) DOI

Yulia A. Pronina,

L. A. Teglyai,

A. I. Ponyaev

et al.

Russian Journal of General Chemistry, Journal Year: 2024, Volume and Issue: 94(1), P. 1 - 44

Published: Jan. 1, 2024

Language: Английский

Citations

2
Metal-Free Regioselective Oxa-Michael Approach to Access Spirooxindole-Fused Tetrahydrofuran/Tetrahydropyran through [3 + 2]/ [4 + 2] Spirocyclization of Methyleneindolinones with Haloalcohols DOI

Amol T. Savekar,

Ramesh A. Gaikwad,

Suresh B. Waghmode

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(13), P. 9389 - 9404

Published: June 24, 2024

An efficient one-pot metal-free, base-catalyzed method has been developed for the regioselective [3 + 2]/[4 2] annulation reactions of electrophilic methyleneindolinones with haloalcohols to furnish spirooxindole derivatives under mild reaction conditions. This afforded corresponding products two contiguous stereocenters including a quaternary center in good excellent yield (up 95%) moderate diastereoselectivities 12.5:1 dr) complete regioselectivity.

Language: Английский

Citations

2
Advances of α-activated cyclic isothiocyanate for the enantioselective construction of spirocycles DOI
Yang Yang, Xingyue Wang, Xinyi Ye

et al.

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(21), P. 4610 - 4621

Published: Jan. 1, 2021

α-Activated cyclic isothiocyanates featuring pharmacophores were efficient percusors for the enantioselective construction of intriguing spirocycles.

Language: Английский

Citations

14
Efficient enantioselective synthesis of CF2H-containing dispiro[benzo[b]thiophene-oxindole-pyrrolidine]s via organocatalytic cycloaddition DOI

Yabo Deng,

Yongzhen Li,

Yalan Wang

et al.

Organic Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 9(1), P. 210 - 215

Published: Nov. 24, 2021

A novel kind of CF 2 H-containing dispiro[benzo[ b ]thiophene-oxindole-pyrrolidine] has been achieved via an organocatalyzed 1,3-dipole reaction.

Language: Английский

Citations

13