Isothiourea-catalysed enantioselective annulation of 2-aminobenzothiophenes with α,β-unsaturated anhydrides DOI

Cheng Niu,

Donghua Xie,

Da‐Ming Du

et al.

Organic Chemistry Frontiers, Journal Year: 2022, Volume and Issue: 9(20), P. 5551 - 5556

Published: Jan. 1, 2022

An isothiourea-catalysed asymmetric Michael/lactamization cascade reaction of 2-aminobenzothiophenes and α,β-unsaturated anhydrides for the enantioselective synthesis benzothienopiperidones with high stereoselectivities was developed.

Language: Английский

Phosphine‐Catalyzed Substitution of Allenoates with Oxindoles: An Approach to 3‐Allenic or 3‐Dienoic Oxindoles DOI

Ze‐ren Yang,

Hou‐Ze Gui,

Min Shi

et al.

ChemistrySelect, Journal Year: 2021, Volume and Issue: 6(36), P. 9709 - 9713

Published: Sept. 23, 2021

Abstract A new method for substitution of allenoate using oxindoles as nucleophilic reagents has been disclosed in this paper upon phosphine catalysis under mild conditions to afford 3‐allenic or 3‐dienoic moderate good yields depending on the substituent at aromatic ring oxindole. According previous works, plausible reaction mechanisms have proposed.

Language: Английский

Citations

3
Isothiourea-catalysed enantioselective annulation of 2-aminobenzothiophenes with α,β-unsaturated anhydrides DOI

Cheng Niu,

Donghua Xie,

Da‐Ming Du

et al.

Organic Chemistry Frontiers, Journal Year: 2022, Volume and Issue: 9(20), P. 5551 - 5556

Published: Jan. 1, 2022

An isothiourea-catalysed asymmetric Michael/lactamization cascade reaction of 2-aminobenzothiophenes and α,β-unsaturated anhydrides for the enantioselective synthesis benzothienopiperidones with high stereoselectivities was developed.

Language: Английский

Citations

1