Organocatalytic Enantioselective Chloroiminocyclization for the Synthesis of Imidazoline DOI
Qifeng Guo,

Zhitao Lai,

Tian Zeng

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(26), P. 5592 - 5596

Published: June 24, 2024

Imidazoline is an important scaffold in organic synthesis and a pharmacophore medicinal chemistry. We apply basic imines as nucleophiles for the catalytic asymmetric chloroiminocyclization to furnish tetrasubstituted stereocenter-containing imidazolines excellent yields enantioselectivities. The reaction can be conducted polar solvent acetonitrile under concentrated conditions.

Language: Английский

Opportunities and Regulatory Challenges of Functional Foods and Nutraceuticals During COVID-19 Pandemic DOI
Jobin Jose,

Keyidaule Ndang,

Madhusoodhana Ballakkuraya Chethana

et al.

Current Nutrition & Food Science, Journal Year: 2024, Volume and Issue: 20(10), P. 1252 - 1271

Published: March 1, 2024

: The novel Coronavirus has brought global mortality, disruption, and a significant loss of life. A compromised immune system is known risk factor for all viral influenza infections. Due to the perceived “immune-boosting” properties nutraceutical products, sales dietary supplements have grown globally. In recent years, consumers increasingly demanded products rather than curative synthetic medicines preventive therapies coronavirus disease outbreak 2019 (COVID-19). Healthy foods nutraceuticals become daily diet plans consumers. Although there been an increase in demand, no such regulation harmonized process, which stands as barrier approval these products. Therefore, many misbranded spurious are entering market, may harm This article focuses on role functional management COVID-19 also different regulations each country compare similarities differences following countries: India, USA (United States America), EU (European Union), China. comparative study USA, Europe, China shows that difference regarding regulations; however, despite differences, it observed same underlying objective, i.e., ensuring safety by maintaining product quality.

Language: Английский

Citations

1

Organocatalytic Enantioselective Chloroiminocyclization for the Synthesis of Imidazoline DOI
Qifeng Guo,

Zhitao Lai,

Tian Zeng

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(26), P. 5592 - 5596

Published: June 24, 2024

Imidazoline is an important scaffold in organic synthesis and a pharmacophore medicinal chemistry. We apply basic imines as nucleophiles for the catalytic asymmetric chloroiminocyclization to furnish tetrasubstituted stereocenter-containing imidazolines excellent yields enantioselectivities. The reaction can be conducted polar solvent acetonitrile under concentrated conditions.

Language: Английский

Citations

0