Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
This
study
describes
a
pioneering
visible-light-induced
phosphine-catalyzed
halogen-atom
transfer
(XAT)
strategy
that
heralds
new
era
in
the
difunctionalization
of
[1.1.1]propellane.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 14, 2024
Photosynthesis,
converting
sustainable
solar
energy
into
chemical
energy,
has
emerged
as
a
promising
craft
to
achieve
diverse
organic
transformations
due
its
mild
reaction
conditions,
sustainability,
and
high
efficiency.
The
synthesis
of
sulfonated
compounds
drawn
significant
attention
in
the
pharmaceuticals,
agrochemicals,
materials
industries
unique
structure
electronic
properties
sulfonyl
groups.
Over
past
decades,
many
photocatalytic
sulfonylation
reactions
have
been
developed.
In
this
review,
recent
advances
photocatalyzed
reviewed
since
2020,
with
primary
focus
on
discussing
design
mechanism.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(12), P. 2758 - 2763
Published: April 24, 2024
Abstract
Herein,
we
present
a
(NH
4
)
2
S
O
8
mediated
difunctionalization
reaction
of
aryl
alkenes
with
quinoxalinones
and
P(O)SH
compounds.
This
method
enables
the
synthesis
various
phosphorothioate‐containing
quinoxalin‐2(1
H
)‐one
derivatives
(46
examples)
in
37–79%
yields.
The
is
compatible
range
functional
groups
easily
adaptable
to
large‐scale
synthesis.
Preliminary
studies
suggest
involvement
phosphorothioate
radicals
these
transformations.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(8), P. 5371 - 5381
Published: March 29, 2024
A
facile
and
eco-friendly
photoinduced
dehydrogenative
amination
of
quinoxalin-2(1H)-ones
with
aliphatic
amines
without
any
metal,
strong
oxidant,
photocatalyst
has
been
established
for
the
first
time.
This
reaction
proceeding
efficiently
air
as
sole
oxidant
at
room
temperature
obtains
a
wide
range
3-aminoquinoxaline-2(1H)-ones
in
high
yields
excellent
functional
group
tolerance.
The
mechanistic
studies
show
an
interesting
involvement
photosensitizer,
which
eliminates
requirement
external
photocatalysts.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(26), P. 5482 - 5487
Published: June 24, 2024
An
efficient
synthesis
of
quinoxaline-fused
aza-bicyclo[2.1.1]hexanes
bearing
multiple
quaternary
carbon
centers
via
the
intermolecular
[2π+2σ]
cycloaddition
bicyclo[1.1.0]butanes
and
quinoxalin-2(1H)-ones,
facilitated
by
Lewis
acid
catalysis,
is
presented.
This
reaction
carried
out
under
mild
conditions
exhibits
a
broad
substrate
scope
excellent
functional
group
tolerance.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(37), P. 7949 - 7955
Published: Sept. 11, 2024
A
novel
electron
donor-acceptor
(EDA)
complex/copper
catalysis
model
has
been
proposed
for
the
construction
of
2,3-diarylpropionitriles
under
visible
light
conditions.
The
developed
protocol
proceeds
via
intermolecular
charge
transfer
between
photoactive
EDA
complex
dibutamine
(DBA),
aryl
thianthrenium
salts,
and
trimethylsilyl
cyanide
(TMSCN),
followed
by
a
copper
catalytic
cycle.
UV-vis
absorption
measurements
confirm
participation
complexes
as
reactive
intermediates.
This
three-component
process
smoothly
in
presence
pharmaceutically
relevant
core
structures
sensitive
functional
groups,
which
offers
possibility
precise
editing
drug
molecules
with
important
scaffolds.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(9), P. 6334 - 6344
Published: April 15, 2024
A
one-pot
strategy
for
deoxygenative
alkylation
of
alcohols
with
quinoxalin-2(1H)-ones
was
developed
by
using
xanthate
salts
as
alcohol-activating
groups
radical
generation
in
the
presence
tricyclohexylphosphine
under
visible-light-promoted
conditions.
The
remarkable
features
this
reaction
include
a
broad
substrate
scope,
excellent
functional
group
tolerance,
mild
conditions,
and
simple
operation.
Moreover,
synthetic
utility
validated
success
two-step
reactions,
scale-up
synthesis,
chemoselective
monodeoxygenation
diols.
