Photocatalytic 1,3-Oxyheteroarylation of Aryl Cyclopropanes with Azine N-oxides DOI Creative Commons
Doyoung Kim, H. L. Ju, Wooseok Lee

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(48), P. 20433 - 20439

Published: Jan. 1, 2024

Developed a difunctionalization method for aryl cyclopropanes using azine N -oxides as bifunctional reagents, generating β-heteroaryl ketones. This enables the use of previously challenging electron-deficient cyclopropanes.

Language: Английский

Nickel‐Catalyzed Asymmetric Reductive 1,4‐ and 1,5‐Dicarbofunctionalization† DOI Open Access
Yutong Xiang,

Chang Zhang,

Chuan Wang

et al.

Chinese Journal of Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Comprehensive Summary Herein, we present the first examples of asymmetric reductive 1,4‐dicarbofunctionalization 1,3‐dienes and 1,5‐dicarbofunctionalization vinylcyclopropanes, which proceed under catalysis a chiral nickel/bis‐imidazoline complex using alkyl halides aryl iodides or alkenyl bromides as electrophilic coupling partners. In these highly enantioselective transformations operating in radical relay mechanism, C(sp 3 )‐ 2 )‐type carbo‐moieties are respectively installed on terminal internal position with newly formed olefinic unit high E ‐selectivity.

Language: Английский

Citations

0
Electrochemical 1,5-chlorosulfonylation and 1,5-hydrosulfonylation of vinylcyclopropanes DOI
Xin Zhang, Wei Li, Yuxiang Zhou

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(19), P. 5564 - 5572

Published: Jan. 1, 2024

This study reports the electrochemical reaction of vinylcyclopropanes with sulfonyl chlorides, resulting in 1,5-hydrosulfonylation and 1,5-chlorosulfonylation.

Language: Английский

Citations

1
Access to Vinyl gem‐Difluorinated Cyclopropanes via Photopromoted Palladium‐Catalyzed Heck Reaction DOI
Bin Li,

Quanxiang Feng,

Jingjing Yuan

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 18, 2024

Abstract A photopromoted Pd‐catalyzed Heck reaction of gem ‐difluorocyclopropyl bromides (DFCBs) with styrenes to deliver vinyl ‐difluorinated cyclopropanes (VDFCs) under mild conditions has been developed. The demonstrates good functional group compatibility while providing high E/Z ratio the products. Furthermore, desired VDFCs can be easily transformed into fluorinated cyclic/acyclic architectures, which may broaden its applications in organic synthesis.

Language: Английский

Citations

0
Photocatalytic 1,3-Oxyheteroarylation of Aryl Cyclopropanes with Azine N-oxides DOI Creative Commons
Doyoung Kim, H. L. Ju, Wooseok Lee

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(48), P. 20433 - 20439

Published: Jan. 1, 2024

Developed a difunctionalization method for aryl cyclopropanes using azine N -oxides as bifunctional reagents, generating β-heteroaryl ketones. This enables the use of previously challenging electron-deficient cyclopropanes.

Language: Английский

Citations

0