The Role of Hydrogen Bond Interactions in Crystal Formation of Pyrrolo-Azines Alcohols

Crystals, Journal Year: 2025, Volume and Issue: 15(1), P. 78 - 78

Published: Jan. 15, 2025

New secondary alcohols of type Ar-CHOH-hetaryl and MeCHOH-hetaryl, the radical hetaryl being a pyrroloazine, were investigated in solid state by X-ray single-crystal diffraction analysis, Hirshfeld analysis DFT methods to assess their crystallographic features. One most important features is presence hydroxyl group bonded an asymmetric carbon atom which was involved strong hydrogen bonds. The driving force crystal packing H-bond with O-H···O=C/N≡C bonds considered as comparative carboxylic acids. These structural properties binding affinity might lead enhanced bioavailability these particular pyrrolo-azines

Language: Английский

Palladium Iodide Catalyzed Oxidative Carbonylations

Tetrahedron Chem, Journal Year: 2024, Volume and Issue: 12, P. 100107 - 100107

Published: Nov. 1, 2024

Language: Английский