Electroreductively driven C–H functionalization of arenes DOI
Pengfei Xie,

Anzai Shi,

Youai Qiu

et al.

Chem Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 101359 - 101359

Published: April 1, 2025

Language: Английский

Cathodic Deoxygenative Alkylation of Nitro(hetero)arenes with Organic Halides DOI
Ziliang Wang, Jianfeng Zhou,

Z. M. Wang

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

We have realized a cathodic deoxygenative alkylation between nitro(hetero)arenes and organic halides, employing bis(pinacolato)diboron (B2pin2) LiCl as additives to trap stabilize the generated alkyl radicals carbanions, thereby facilitating efficient N-O cleavage selective C-N bond formation. The protocol offers an economical method for synthesis of multiple aromatic(hetero) amines, without need reactive reductants exclusion air moisture. Notably, is distinguished by scalability, broad functional group compatibility, safe mild conditions, demonstrating practicality in late-stage modification various bioactive compounds.

Language: Английский

Citations

0
Electroreductively driven C–H functionalization of arenes DOI
Pengfei Xie,

Anzai Shi,

Youai Qiu

et al.

Chem Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 101359 - 101359

Published: April 1, 2025

Language: Английский

Citations

0