Journal of International Medical Research,
Journal Year:
2024,
Volume and Issue:
52(12)
Published: Dec. 1, 2024
Objective
We
examined
fluctuations
in
emergency
department
(ED)
visits
for
nonspecific
back
and
neck
pain
during
the
COVID-19
pandemic
explored
potential
contributing
factors.
Methods
This
retrospective
cohort
study
included
patients
who
presented
to
ED
with
between
January
2019
December
2021.
Demographic
data,
visit
frequencies,
clinical
outcomes
were
analyzed
assess
impact
of
on
patterns.
Results
A
total
1245
recorded.
Visits
decreased
by
30%
peak
pandemic,
a
gradual
return
baseline
mid-2021.
No
significant
changes
patient
demographics
or
noted
pandemic.
However,
proportional
increase
was
observed.
Conclusions
The
observed
decline
may
be
linked
pandemic-related
concerns,
such
as
fear
exposure
hospital
reduced
activities.
increased
highlights
influence
stress
lifestyle
changes.
Visit
patterns
rebounded
eased,
indicating
temporary
decrease
unrelated
condition
severity.
temporarily
affected
pain.
Further
research
is
needed
explore
long-term
effects
health
care
utilization.
International Journal of Mental Health Nursing,
Journal Year:
2024,
Volume and Issue:
33(4), P. 817 - 833
Published: Feb. 8, 2024
Abstract
Service
providers
find
it
difficult
to
implement
Physical
Exercise
(PE)
strategies
in
routine
care
within
inpatient
mental
health
settings
even
though
they
perceive
be
an
effective
therapy,
with
a
robust
evidence
base.
Identifying
barriers
that
exist
can
assist
the
development
of
future
interventions
and
support
PE
services
being
introduced
into
settings.
The
aim
this
systematic
review
was
synthesise
on
or
perceived
amongst
service
users
when
incorporating
as
intervention
Using
narrative
synthesis
approach,
four
main
themes
were
identified:
(i)
Barriers
relating
users'
physical
health,
(ii)
Factors
providers,
(iii)
Environmental
factors
(iv)
Cultural
factors.
Both
need
more
knowledge
implementing
Tailored
programmes
for
are
warranted,
specialist
roles
staff
developed.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(20), P. 6149 - 6149
Published: Oct. 15, 2024
Low
back
pain
(LBP)
is
most
common
syndrome
in
Europe,
affecting
approximately
50%
of
European
citizens.
LBP
a
complex
condition
that
negatively
affects
many
aspects
an
individual's
life
such
as
work
productivity,
mobility,
and
mental
health.
The
aim
this
study
to
assess
the
impact
associated
with
chronic
on
patients'
quality
life.
Healthcare,
Journal Year:
2025,
Volume and Issue:
13(5), P. 447 - 447
Published: Feb. 20, 2025
Background:
Non-specific
low
back
pain
is
the
leading
cause
of
years
lived
with
disability
worldwide.
The
present
study
investigates
non-specific
pain,
perceptions
and
due
to
among
Brazilian
Jiu
Jitsu,
Muay
Thai
Boxing
athletes.
Methods:
included
90
amateur
athletes
(aged
18-45
years;
M
=
28.97,
SD
5.88).
completed
valid
reliable
Pain
Beliefs
Perceptions
Inventory
(PBPI),
Quebec
Disability
Scale
(QPDS)
Short-Form
McGill
Questionnaire
(SF-MPQ)
which
includes
Visual
Analogue
(10
cm
VAS
0-10
rating
system)
Present
Intensity
index
(PPI).
Results:
results
revealed
that
majority
rated
their
as
(SF-MPQ:
12.34,
8.91;
VAS:
1.65,
1.82;
PPI:
2.10,
1.08)
(QPDS:
18.98,
22.71).
Also,
disagreed
was
mysterious
or
persistent
high
duration
(PBPI:
1.43,
2.23).
Between
three
martial
arts,
Jitsu
showed
statistically
significantly
(a)
higher
emotional
sensational
intensity
(x2(2)
15.73;
p
<
0.001;
x2(2)
19.34;
0.001),
(b)
(x2(2)=
25.30;
0.001)
(c)
more
mysterious,
9.32;
0.05)
than
a
few
correlations
were
found
between
age
perception
only
in
arts
Conclusions:
Further
research
required
elucidate
biomechanical
psychological
factors
contributing
these
differences
Journal of Neurochemistry,
Journal Year:
2025,
Volume and Issue:
169(4)
Published: April 1, 2025
Lumbar
disc
herniation
(LDH)
is
a
common
chronic
orthopedic
condition
characterized
by
the
protrusion
of
nucleus
pulposus
tissue,
leading
to
low
back
and
leg
pain.
Its
pathophysiology
remains
poorly
understood.
The
aim
this
study
was
investigate
whether
demethylase
Fat
mass
obesity-associated
protein
(FTO)
mediates
local
translation
P2X3
receptors
(P2X3R)
in
rat
model
LDH.
effect
process
on
excitability
dorsal
root
ganglion
(DRG)
cells
also
examined,
which
may
elucidate
peripheral
molecular
mechanisms
underlying
specific
pain
sensitivity
LDH
models
were
established
male
Sprague-Dawley
rats.
Behavioral
tests
assessed
mechanical
thermal
thresholds
motor
function.
expression
P2X3R
FTO
DRG
investigated
RT-qPCR,
Western
blot,
immunofluorescence.
knocked
down,
methylation
examined
MeRIP
validate
their
roles.
IL-1β
IL-6
levels
quantified
ELISA.
Protein
interactions
predicted
using
AutoDock,
neuronal
patch
clamp
recordings.
Compared
with
Sham
group,
group
showed
reduction
threshold
hind
limbs.
There
no
significant
differences
increased
group.
DRG,
localized
mainly
cell
membrane
colocalized
NeuN.
Intrathecal
injection
P2X3R-siRNA
FTO-siRNA
effective
increasing
thresholds,
reducing
FTO,
decreasing
neurons,
IL-6.
RNA
Methylation
Immunoprecipitation
(MeRIP)
analysis
revealed
reduced
m6A
modification
mRNA
AutoDock
hydrogen
bond
between
P2X3R.
These
findings
suggest
that
regulates
DRG.
This
influences
contributes
LDH-induced
hyperalgesia.
Pain and Therapy,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 29, 2025
Low
back
pain
(LBP)
is
the
primary
factor
contributing
to
years
lived
with
disability.
In
view
of
close
correlation
between
functions
body,
which
cannot
be
examined
piecemeal
but
as
an
integrated
system,
a
holistic
approach
allows
for
comprehensive
assessment
patient.
The
main
objective
this
study
evaluate
impact
face-to-face
or
remote
rehabilitation
treatment
on
psychosocial
aspects
patients
chronic
low
(CLBP)
examining
all
possible
related
dimensions:
cognitive
function,
anxiety
and
depression,
perception,
adherence,
sexual
sphere,
family
dynamics,
social
support,
dysfunctional
communication,
quality
life
(QoL),
while
also
considering
attribution
causes.
This
prospective,
randomized,
controlled
trial
blinded
outcome
assessors
evaluates
functioning
86
LBP.
Participants
divided
into
two
groups
compare
tele-rehabilitation
1:1
randomization
based
web-based
system
will
undergo
neuropsychological,
psychological,
associated
clinical
condition
through
standardized
tests
ad
hoc
questionnaires
at
enrollment
(T0),
after
1
month
(T1),
2
months
(T2),
6
(T3).
analysis
involves
descriptive
statistics,
ANOVA,
effects
outcomes
multiple
time
points.
We
expect
provide
comprehensive,
in-depth,
understanding
patient,
shedding
light
challenges
they
may
face
in
managing
LBP
(CLBP).
Repeated
administration
allow
us
monitor
patient
over
time,
assess
any
changes
their
health
status,
structure
intervention
tailored
needs.
By
emphasizing
these
often
neglected
areas
multi-step
assessment,
it
quantify
analyze
how
risk
factors
can
affect
patients'
wellbeing
hinder
process
recovery.
Registered
Clinicaltrials.gov
(ID:
NCT06895317).
BMJ Open,
Journal Year:
2025,
Volume and Issue:
15(4), P. e096099 - e096099
Published: April 1, 2025
Kinesiophobia
is
a
significant
factor
which
influences
the
prognosis
of
patients
with
chronic
non-specific
low
back
pain
(CNLBP).
The
restriction
functional
training
can
severely
impede
recovery
and
contribute
to
negative
emotional
states
(including
anxiety
depression)
heightened
risk
insomnia
while
exacerbating
economic
burden
on
patients.
Although
several
randomised
controlled
trials
have
evaluated
effects
various
non-pharmacological
interventions
kinesiophobia
in
CNLBP,
their
relative
efficacy
potential
adverse
remain
ambiguous.
This
study
will
conduct
systematic
review
network
meta-analysis
identify
intervention
may
represent
most
effective
treatment
for
CNLBP.
Comprehensive
searches
be
conducted
across
English
Chinese
databases
Cochrane
Library,
PubMed,
Scopus,
Springer,
Embase,
Wanfang
Data,
Chongqing
VIP
Database
China
National
Knowledge
Infrastructure)
from
date
inception
20
November
2024.
Only
or
studies
considered
analysis.
primary
outcomes
include
reduction
secondary
movement
phobia
associated
alleviation
enhancement
status
lumbar
muscles.
Bias
Risk
Assessment
Tool
used
bias
assessment.Pairwise
performed
by
Review
Manager
V.5.3
software,
Stata
V.16.0
Open
BUGS
V.3.2.3
software
meta-analysis.
Grading
Recommendations,
Assessment,
Development
Evaluation
framework
employed
assess
quality
evidence.
All
data
included
this
derived
literature;
therefore,
ethical
approval
not
necessary.
findings
disseminated
via
peer-reviewed
journals
academic
conferences.
CRD42024605343.
BMC Musculoskeletal Disorders,
Journal Year:
2025,
Volume and Issue:
26(1)
Published: May 1, 2025
To
validate
the
effectiveness
of
six
exercise
therapies
in
treating
low
back
pain
using
Meta-analysis
methods,
and
to
propose
optimal
duration,
frequency,
cycle.
Databases
such
as
PubMed,
EMBASE,
Cochrane
Library,
China
National
Knowledge
Infrastructure,
VIP
Data,
SinoMed
were
searched.
The
RevMan
5.4
tool
was
utilized
conduct
subgroup
analyses
on
eight
moderating
variables,
including
types
exercise,
cycle,
sample
size,
study
quality,
outcome
indicator,
comparisons
different
intervention
methods
with
control
group
from
42
included
studies.
Random
effects
models
employed
test
for
overall
effects,
heterogeneity,
bias.
effect
size
significant
(SMD=
-1.21,
P
<
0.00001).
Subgroup
showed
yoga
had
largest
-1.97,
=
0.0001).
Exercise
duration
≤
30
min
-1.31,
0.0001),
frequencies
>
4
times/week
-1.56,
0.00001),
cycles
weeks
-1.61,
0.00001)
most
effective.
Sample
sizes
30~60
cases
-1.36,
studies
moderate
bias
risk
-1.37,
also
large
effects.
Oswestry
Disability
Index
scores
demonstrated
-3.35,
physical
factors
-1.85,
All
effectively
alleviated
pain,
showing
best
results.
protocol
involved
not
exceeding
per
session,
frequency
more
than
times
week,
cycle
weeks.
Additionally,
interventions
exhibited
improvements
pain.
Children,
Journal Year:
2025,
Volume and Issue:
12(6), P. 702 - 702
Published: May 29, 2025
This
narrative
review
provides
an
overview
of
the
link
between
sensorimotor
system,
cognition,
emotion
and
pain
syndromes
in
persons
due
to
deconditioning
or
delayed
development,
then
applied
with
cerebral
palsy
(CP).
The
brain
damage
that
occurs
before,
during
even
after
birth
pathophysiologically
alters
structure
subsequent
function
function,
which
is
inseparably
linked
emotion,
behavior
pain.
results
a
functional
developmental
disorder
also
affects
neuromatrix
graded
manner
chronic
deconditioning.
It
basis
for
both
primary
secondary
degenerative
diseases.
leads
increasing
prevalence
syndromes,
may
be
very
high
CP.
Thus,
CP
disposing
factor
causal
nociplastic
pain,
defined
as
persistent
arising
from
altered
nociception
without
evidence
tissue
somatosensory
damage.
Therapy
interventions
are
crucial
optimize
movement,
cognition
well
reduction
Sports,
Journal Year:
2024,
Volume and Issue:
12(7), P. 190 - 190
Published: July 11, 2024
The
therapeutic
actions
indicated
for
low
back
pain,
in
addition
to
physiotherapy,
include
mobilization
of
the
affected
segment,
as
it
is
assumed
that
a
loss
mobility
may
contribute
patient’s
pain.
aim
this
study
was
investigate
influence
pain
on
degrees
spinal
young
adults.
Eighty-six
volunteers
participated
study.
Fingertip-to-floor
distance,
Schöber’s
test,
fingertip-to-floor
lateral
flexion
GHQ-12,
Fear-Avoidance
Beliefs
Questionnaire
and
STarT
Back
Screening
Tool
were
used.
There
statistically
significant
differences
between
two
groups
(pain
no
pain)
(Schöber’s
test
side
flexion)
showing
greater
group
with
However,
showed
less
rotational
mobility.
presence
or
absence
had
an
impact
individual’s
sporting
practice
perception
they
able
carry
out
their
activities
normally.
Young
adults
idiopathic
some
relation
spine
different
planes
movement
(flexion
flexion),
conditioning
quality
life
sports
practice.