CFD‐Based Optimization of a Dielectrophoretic Device to Isolate CTCs

Electrophoresis, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Cancer cells that have separated from the main tumor and entered bloodstream are known as circulating (CTCs). Once there, they may spread to other parts of body cause metastases. This work proposes a novel inertial-based dielectrophoresis (DEP) device designed for separation CTCs red blood (RBCs). The microchannel features rectangular zigzag segment combined with circular curved section, optimized improve efficiency by integrating inertial DEP forces. Numerical simulations conducted evaluate effects depth, applied voltage frequency, Reynolds number (Re) on trajectory cells. identify four optimal scenarios achieve 100% efficiency. Early cancer diagnosis treatment benefit use proposed CTC detection.

Language: Английский

Size-based separation of fine mineral particles using inertial microfluidics: A case of jarosite and anglesite

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 500, P. 157509 - 157509

Published: Nov. 1, 2024

Language: Английский