Biocompatible microneedles with engineered indentation design fabricated via vat photopolymerization for enhanced transdermal drug delivery DOI

Aqila Che Ab Rahman,

Siyoung Yang,

Sooman Lim

et al.

European Polymer Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113818 - 113818

Published: Feb. 1, 2025

Language: Английский

Lightweight and Strong Cellulosic Triboelectric Materials Enabled by Cell Wall Nanoengineering DOI
Xiuzhen Li, Jinlong Wang, Yanhua Liu

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: 24(10), P. 3273 - 3281

Published: March 1, 2024

As intelligent technology surges forward, wearable electronics have emerged as versatile tools for monitoring health and sensing our surroundings. Among these advancements, porous triboelectric materials garnered significant attention their lightness. However, face the challenge of improving structural stability to further enhance accuracy sensors. In this study, a lightweight strong cellulosic material is designed by cell wall nanoengineering. By tailoring structure, shows high mechanical strength 51.8 MPa. The self-powered sensor constructed has sensitivity 33.61 kPa–1, fast response time 36 ms, excellent pressure detection durability. Notably, still enables performance after exposure 200 °C achieves real-time feedback human motion, thereby demonstrating great potential in field electronic devices.

Language: Английский

Citations

55

A Highly Stretchable, Conductive, and Transparent Bioadhesive Hydrogel as a Flexible Sensor for Enhanced Real‐Time Human Health Monitoring DOI
Arpita Roy,

Shea Zenker,

Saumya Jain

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(35)

Published: June 21, 2024

Real-time continuous monitoring of non-cognitive markers is crucial for the early detection and management chronic conditions. Current diagnostic methods are often invasive not suitable at-home monitoring. An elastic, adhesive, biodegradable hydrogel-based wearable sensor with superior accuracy durability real-time human health developed. Employing a supramolecular engineering strategy, pseudo-slide-ring hydrogel synthesized by combining polyacrylamide (pAAm), β-cyclodextrin (β-CD), poly 2-(acryloyloxy)ethyltrimethylammonium chloride (AETAc) bio ionic liquid (Bio-IL). This novel approach decouples conflicting mechano-chemical effects arising from different molecular building blocks provides balance mechanical toughness (1.1 × 10

Language: Английский

Citations

51

Organic Electronics in Biosensing: A Promising Frontier for Medical and Environmental Applications DOI Creative Commons
Jyoti Kaushal,

Pratima Raut,

Sanjay Kumar

et al.

Biosensors, Journal Year: 2023, Volume and Issue: 13(11), P. 976 - 976

Published: Nov. 7, 2023

The promising field of organic electronics has ushered in a new era biosensing technology, thus offering frontier for applications both medical diagnostics and environmental monitoring. This review paper provides comprehensive overview electronics’ remarkable progress potential applications. It explores the multifaceted aspects materials devices, thereby highlighting their unique advantages, such as flexibility, biocompatibility, low-cost fabrication. delves into diverse range biosensors enabled by electronics, including electrochemical, optical, piezoelectric, thermal sensors, showcasing versatility detecting biomolecules, pathogens, pollutants. Furthermore, integrating wearable devices Internet Things (IoT) ecosystem is discussed, wherein they offer real-time, remote, personalized monitoring solutions. also addresses current challenges future prospects biosensing, emphasizing breakthroughs medicine, sustainability, advancement human health well-being.

Language: Английский

Citations

42

Electronic Skin for Health Monitoring Systems: Properties, Functions, and Applications DOI

Xichen Yang,

Wenzheng Chen, Qunfu Fan

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(31)

Published: May 17, 2024

Abstract Electronic skin (e‐skin), a skin‐like wearable electronic device, holds great promise in the fields of telemedicine and personalized healthcare because its good flexibility, biocompatibility, conformability, sensing performance. E‐skin can monitor various health indicators human body real time over long term, including physical (exercise, respiration, blood pressure, etc.) chemical (saliva, sweat, urine, etc.). In recent years, development materials, analysis, manufacturing technologies has promoted significant e‐skin, laying foundation for application next‐generation medical devices. Herein, properties required e‐skin monitoring devices to achieve long‐term precise summarize several detectable field are discussed. Subsequently, applications integrated systems reviewed. Finally, current challenges future directions this This review is expected generate interest inspiration improvement systems.

Language: Английский

Citations

39

Advances in wearable respiration sensors DOI
Sophia Shen, Qian Zhou,

Guorui Chen

et al.

Materials Today, Journal Year: 2024, Volume and Issue: 72, P. 140 - 162

Published: Jan. 1, 2024

Language: Английский

Citations

34

Layer-by-layer designer nanoarchitectonics for physical and chemical communications in functional materials DOI Creative Commons
Katsuhiko Ariga, Jingwen Song, Kohsaku Kawakami

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(16), P. 2152 - 2167

Published: Jan. 1, 2024

In nanoarchitectonics approaches, rational physical and chemical communications will lead to the development of more advanced functional materials. Layer-by-layer assembly can be a powerful tool for this purpose, as exemplified in feature paper.

Language: Английский

Citations

23

Liquid Metal–Polymer Conductor-Based Conformal Cyborg Devices DOI
Jie Qi, Shuaijian Yang, Yizhou Jiang

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2081 - 2137

Published: Feb. 23, 2024

Gallium-based liquid metal (LM) exhibits exceptional properties such as high conductivity and biocompatibility, rendering it highly valuable for the development of conformal bioelectronics. When combined with polymers, metal–polymer conductors (MPC) offer a versatile platform fabricating cyborg devices, enabling functions sensing, restoration, augmentation within human body. This review focuses on synthesis, fabrication, application MPC-based devices. The synthesis functional materials based LM fabrication techniques devices are elucidated. provides comprehensive overview encompassing their applications in sensing diverse signals, therapeutic interventions, augmentation. objective this is to serve resource that bridges gap between potential biomedical applications.

Language: Английский

Citations

23

Wireless Battery-free and Fully Implantable Organ Interfaces DOI
A. K. Bhatia, Jessica Hanna, Tucker Stuart

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2205 - 2280

Published: Feb. 21, 2024

Advances in soft materials, miniaturized electronics, sensors, stimulators, radios, and battery-free power supplies are resulting a new generation of fully implantable organ interfaces that leverage volumetric reduction mechanics by eliminating electrochemical storage. This device class offers the ability to provide high-fidelity readouts physiological processes, enables stimulation, allows control over organs realize therapeutic diagnostic paradigms. Driven seamless integration with connected infrastructure, these devices enable personalized digital medicine. Key advances carefully designed material, electrophysical, electrochemical, electromagnetic systems form implantables mechanical properties closely matched target deliver functionality supports sensors stimulators. The elimination operation, anywhere from acute, lifetimes matching subject physical dimensions imperceptible operation. review provides comprehensive overview basic building blocks related topics such as implantation, delivery, sterilization, user acceptance. State art examples categorized system an outlook interconnection advanced strategies for computation leveraging consistent influx elevate this current battery-powered is highlighted.

Language: Английский

Citations

17

Therapeutic Potential of Microneedle Assisted Drug Delivery for Wound Healing: Current State of the Art, Challenges, and Future Perspective DOI

Devesh Kumar,

Shubham Pandey,

Jailani Shiekmydeen

et al.

AAPS PharmSciTech, Journal Year: 2025, Volume and Issue: 26(1)

Published: Jan. 8, 2025

Language: Английский

Citations

4

Permeable and Durable Liquid‐Metal Fiber Mat as Implantable Physiological Electrodes with Long‐Term Biocompatibility DOI Open Access

Ningjing Zhou,

Jiujiang Ji, Ruixiang Qu

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract Implantable physiological electrodes provide unprecedented opportunities for real‐time and uninterrupted monitoring of biological signals. Most implantable electronics adopt thin‐film substrates with low permeability that severely hampers tissue metabolism, impeding their long‐term biocompatibility. Recent innovations have seen the advent permeable through strategic modification liquid metals (LMs) onto porous substrates. However, durability these is limited by inherent poor wettability LMs, particularly within intricate 3D skeleton substrate. Herein, study reports a spatial tuning strategy solves issue LMs substrates, enabling LM high The demonstrates use as neural interface to realize in vivo acquisition electrocardiograph electrocorticogram signals biocompatibility signal‐to‐noise ratio. This work promising direction rational design durable bioelectronics

Language: Английский

Citations

2