Green Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 100225 - 100225
Published: Feb. 1, 2025
Language: Английский
Environmental Toxicology and Chemistry, Journal Year: 2020, Volume and Issue: 40(3), P. 631 - 657
Published: Nov. 17, 2020
Abstract We synthesize current understanding of the magnitudes and methods for assessing human wildlife exposures to poly‐ perfluoroalkyl substances (PFAS). Most exposure assessments have focused on 2 5 legacy PFAS, are typically limited targeted PFAS (up ~30 substances). However, shifts in chemical production occurring rapidly, detecting not kept pace with these changes. Total fluorine measurements complemented by suspect screening using high‐resolution mass spectrometry thus emerging as essential tools assessment. Such enable researchers better understand contributions from precursor compounds that degrade into terminal acids. Available data suggest diet is major pathway some but there large variability across populations compounds. Additional total media fraction unidentified organofluorine needed. Drinking water has been established source contaminated communities. As supplies remediated, general population, dust, personal care products, indoor environments, other sources may be more important. A challenge lack statistically representative population surveys. For wildlife, bioaccumulation processes differ substantially between neutral lipophilic organic compounds, prompting a reevaluation traditional metrics. There evidence both phospholipids proteins important tissue partitioning accumulation PFAS. New mechanistic models being developed will assist risk evaluations. Environ Toxicol Chem 2021;40:631–657. © 2020 SETAC
Language: Английский
Citations
534
Journal of Environmental Management, Journal Year: 2021, Volume and Issue: 301, P. 113879 - 113879
Published: Oct. 4, 2021
Language: Английский
Citations
107
Eco-Environment & Health, Journal Year: 2022, Volume and Issue: 1(2), P. 117 - 131
Published: June 1, 2022
Widespread application of poly- and per-fluoroalkyl substances (PFAS) has resulted in some being ubiquitous environmental matrices. That their resistance to degradation have allowed them accumulate wildlife humans with potential for toxic effects. While specific concern been phased-out or banned, other PFAS that are emerging as alternative still produced released into the environment. This review focuses on describing three emerging, replacement PFAS: perfluoroethylcyclohexane sulphonate (PFECHS), 6:2 chlorinated polyfluoroalkyl ether sulfonate (6:2 Cl-PFAES), hexafluoropropylene oxide dimer acid (HFPO-DA). By summarizing physicochemical properties, fate transport, potencies comparison compounds, this offers insight viabilities these chemicals substances. Using chemical scoring ranking assessment model, relative hazards, uncertainties, data gaps each were quantified related perfluorooctane sulfonic (PFOS) perfluorooctanoic (PFOA) based uncertainty scores. The ranked PFOS > Cl-PFAES PFOA HFPO-DA PFECHS according toxicity need future research. Since uses remain uncertain face governmental regulations production bans, will continue emerge world market environment, raising concerns about general lack information mechanisms potencies.
Language: Английский
Citations
91
Trends in Environmental Analytical Chemistry, Journal Year: 2023, Volume and Issue: 37, P. e00198 - e00198
Published: Feb. 10, 2023
Language: Английский
Citations
59
Environmental Science & Technology Letters, Journal Year: 2023, Volume and Issue: 10(4), P. 292 - 301
Published: March 9, 2023
The comprehensive characterization of per- and polyfluoroalkyl substances (PFASs) is necessary for the effective assessment management risk at contaminated sites. While current analytical methods are capable quantitatively measuring a number specific PFASs, they do not provide complete picture thousands PFASs that utilized in commercial products potentially released into environment. These unmeasured include many PFAS precursors, which may be converted related chemicals through oxidation. total oxidizable precursor (TOP) assay offers means bridging this gap by oxidizing unknown precursors intermediates converting them stable with established standards. application TOP to samples from PFAS-contaminated sites has generated several new insights, but it also presented various technical challenges laboratories. Despite increased literature studies assay, there critical growing method beyond researchers academia. This article outlines benefits using aqueous site assessments suggests ways address some its limitations.
Language: Английский
Citations
53
Toxics, Journal Year: 2023, Volume and Issue: 11(5), P. 446 - 446
Published: May 9, 2023
Per- and polyfluoroalkyl substances (PFASs), highly stable synthetic organic compounds with multiple carbon-fluorine bonds, are emerging as environmental contaminants, toxic, bioaccumulative, environmentally persistent. PFASs strongly resistant to biological chemical degradation, therefore present a challenge researchers scientists for better understanding application of remediation methods biodegradation have become subject strict government regulations. The review summarizes the recent knowledge bacterial fungal degradation PFASs, well enzymes involved in processes transformation/degradation PFASs.
Language: Английский
Citations
45
Case Studies in Chemical and Environmental Engineering, Journal Year: 2024, Volume and Issue: 9, P. 100623 - 100623
Published: Jan. 14, 2024
Alarming concern over the persistence and toxicity of per- polyfluoroalkyl substances (PFAS) in environment has created an imperative need for designing redesigning strategies their detection remediation. Conventional PFAS removal technologies that uses physical, chemical, or biological methods. Increase diversity quantity entering necessitated developing more advanced integrated removal. Despite advances reported this domain, there exist a huge research gap to be mentored tackle problems associated with mitigation combined wide variety environment. The possibility combine other emerging contaminants poses additional threat existing treatment methods thereby stressing continuous monitoring updating processes. This review work aims at understanding structure, entry, fate different types Further in-depth discussion regarding levels is elaborated review. process description recent remediation techniques along significance, limitations integration discussed detail. detailed outlook on advantages insight into recently developed outlined
Language: Английский
Citations
24
The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 960, P. 178297 - 178297
Published: Jan. 1, 2025
Language: Английский
Citations
2
The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 962, P. 178472 - 178472
Published: Jan. 1, 2025
Language: Английский
Citations
2
Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 24, 2025
Per- and polyfluoroalkyl substances (PFAS) are used in a wide range of different industrial consumer applications. However, due to their extreme environmental persistence impacts on human ecosystem health, PFAS have been subject many regulatory activities, including initiatives incentivize industry transition toward PFAS-free alternatives. Although efforts made map all uses PFAS, work is still needed provide an overview potential Based the functional substitution approach, this study develops online database that documents known describes functions provided by these uses, lists alternatives can deliver equivalent or similar evaluates suitability identified replace PFAS. Overall, 325 applications across 18 use categories. In total, 530 identified. screening concerns alternatives, performance compared availability market, it concluded potentially suitable available for 40 For 83 applications, no could be at time should focus further research activities.
Language: Английский
Citations
2