Peanut Rhizosphere Achromobacter xylosoxidans Inhibits Aspergillus flavus Development and Aflatoxin Synthesis by Inducing Apoptosis through Targeting the Cell Membrane DOI

Tongzheng Sun,

Yuxin Wang,

Dongjing Niu

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(31), P. 17572 - 17587

Published: July 29, 2024

Contamination of crop seeds and feed with Aspergillus flavus its associated aflatoxins presents a significant threat to human animal health due their hepatotoxic carcinogenic properties. To address this challenge, researchers have screened for potential biological control agents in peanut soil pods. This study identified promising candidate, strain the nonpigmented bacterium, Achromobacter xylosoxidans ZJS2-1, isolated from rhizosphere Zhejiang Province, China, exhibiting notable antifungal antiaflatoxin activities. Further investigations demonstrated that ZJS2-1 active substances (ZAS) effectively inhibited growth at MIC 60 μL/mL nearly suppressed AFB1 production by 99%. Metabolomic analysis revealed ZAS significantly affected metabolites involved cell wall membrane biosynthesis, leading compromised cellular integrity induced apoptosis A. through release cytochrome c. Notably, targeted SrbA, key transcription factor ergosterol biosynthesis integrity, highlighting crucial role ZJS2-1's biocontrol mechanism. Moreover, infection plant wilt caused can be efficiently alleviated ZAS. Additionally, inhibitory effects on various species, inhibition rates ranging 80 These findings highlight as agent against offering solution enhance food safety protect health.

Language: Английский

Green solvents for the extraction of mycotoxins during the analysis of food products: A Mini-review DOI Open Access
Mohamed S. Abdelfattah

Advances in Basic and Applied Sciences, Journal Year: 2023, Volume and Issue: 1(1), P. 21 - 32

Published: June 1, 2023

Implementing green chemistry concepts in all areas of science for eco-friendly and sustainable scientific research is necessary.A promising area which principles may have a substantial impact on the quality efficiency natural products extraction mycotoxins.These compounds are poisonous to humans frequently found food feed.In this literature review, we present traditional methods mycotoxins during product analysis using toxic organic solvents updated technical information about such as deep-eutectic solvents, supercritical CO2, pressurized hot water.Within various types has been discussed, with an emphasis factors that influence their extraction, molar ratio extracting solvent, temperature, co-solvents, duration, recovery percentage.

Language: Английский

Citations

2
Peanut Rhizosphere Achromobacter xylosoxidans Inhibits Aspergillus flavus Development and Aflatoxin Synthesis by Inducing Apoptosis through Targeting the Cell Membrane DOI

Tongzheng Sun,

Yuxin Wang,

Dongjing Niu

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(31), P. 17572 - 17587

Published: July 29, 2024

Contamination of crop seeds and feed with Aspergillus flavus its associated aflatoxins presents a significant threat to human animal health due their hepatotoxic carcinogenic properties. To address this challenge, researchers have screened for potential biological control agents in peanut soil pods. This study identified promising candidate, strain the nonpigmented bacterium, Achromobacter xylosoxidans ZJS2-1, isolated from rhizosphere Zhejiang Province, China, exhibiting notable antifungal antiaflatoxin activities. Further investigations demonstrated that ZJS2-1 active substances (ZAS) effectively inhibited growth at MIC 60 μL/mL nearly suppressed AFB1 production by 99%. Metabolomic analysis revealed ZAS significantly affected metabolites involved cell wall membrane biosynthesis, leading compromised cellular integrity induced apoptosis A. through release cytochrome c. Notably, targeted SrbA, key transcription factor ergosterol biosynthesis integrity, highlighting crucial role ZJS2-1's biocontrol mechanism. Moreover, infection plant wilt caused can be efficiently alleviated ZAS. Additionally, inhibitory effects on various species, inhibition rates ranging 80 These findings highlight as agent against offering solution enhance food safety protect health.

Language: Английский

Citations

0