The relationship between the severity and complications of Henöch-Schönlein purpura in children and dietary inflammatory index: a retrospective cohort study DOI Creative Commons
Jinshu Chen,

P. S. Chen,

Yijin Song

et al.

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e18175 - e18175

Published: Sept. 24, 2024

Purpose To investigate the association between Dietary Inflammatory Index (DII) and disease severity as well complications in children diagnosed with Henöch-Schönlein purpura (HSP), shedding light on potential influence of dietary factors HSP. Methods A retrospective cohort study was conducted, enrolling aged 2–14 years Participants were divided into low Pro-inflammatory groups based their DII scores. Biomarkers, nutrient intake, blood lipid profiles compared two groups. Spearman correlation analysis performed to assess relationship complications. Results total 115 patients, including 56 patients anti-inflammatory 59 pro-inflammatory dietary, included. The group demonstrated significantly elevated C-reactive protein, tumor necrosis factor-α, interleukin-6, erythrocyte sedimentation rate, white cell count, eosinophils, IgE, consumption calories, carbohydrates, fiber, fat cholesterol, LDL HDL triglycerides, VLDL renal, skin, gastrointestinal, coagulation respiratory comparison group. positively correlated Conclusion highlights inflammatory potential, quantified by DII, Understanding interplay patterns responses pediatric vasculitis has implications for management HSP, emphasizing relevance considering interventions optimize clinical outcomes improve overall well-being affected children.

Language: Английский

Associations of dietary inflammation index and composite dietary antioxidant index with all-cause mortality in COPD patients DOI Creative Commons
Sue Zhao, Yingjie Su, Hongzhong Yang

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 21, 2025

Background Few studies have investigated the effects of both dietary inflammatory index (DII) and composite antioxidant (CDAI) on mortality in patients with Chronic Obstructive Pulmonary Disease (COPD). Our research aimed to explore associations between two indicators all-cause COPD patients. Methods We conducted a prospective cohort analysis based data from six cycles National Health Nutrition Examination Survey (NHANES) dataset 2007 2018. Multivariate Cox proportional hazard models were used analyze DII CDAI COPD. employed restricted cubic spline (RCS) examine dose–response relationship mortality, threshold effect determine inflection point, subgroup interaction tests verify stability results. Results A total 1,457 aged over 40 enrolled study. The median follow-up time was 76.8 months. multivariate hazards model showed that increased associated an increase (HR (95% CI): 1.11(1.04, 1.18), p = 0.002). In contrast, negatively correlated 0.95(0.91, 0.99), 0.01). RCS nonlinear correlation or mortality. maximum pro-inflammatory point 2.32, while is −0.12. Subgroup analyses indicated exposure variables stable most populations. Conclusion Reducing diet increasing can reduce

Language: Английский

Citations

2
Dietary inflammatory index and elevated serum C‐reactive protein: A systematic review and meta‐analysis DOI Creative Commons
Salman Mohammadi, Mahboobe Hosseinikia, Ali Ghaffarian‐Bahraman

et al.

Food Science & Nutrition, Journal Year: 2023, Volume and Issue: 11(10), P. 5786 - 5798

Published: July 6, 2023

Diet can affect the inflammatory state of body. Accordingly, dietary index (DII) has been developed to quantify properties food items. This study sought investigate association between inflammation and odds ratio elevated CRP (E-CRP) through a systematic review meta-analysis study. The International electronic databases PubMed, Web Science (ISI), Scopus were searched until May 2023 find related articles. From 719 studies found in initial search, 14 studies, with total sample size 59,941 individuals, included meta-analysis. calculated pooled (OR) E-CRP highest DII category was 1.39 (95% CI: 1.06, 1.14, test for heterogeneity:

Language: Английский

Citations

11
Relationship between the dietary inflammation index and hypertension in American children and adolescents: findings from the national health and nutrition examination survey 1999–2018 DOI Creative Commons
Li‐Ying Du,

Jiahu Hao,

Kai Yu

et al.

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 3, 2025

This study aimed to examine the relationship between dietary inflammatory index (DII) and hypertension in children adolescents using data from National Health Nutrition Examination Survey (NHANES) conducted 1999 2018. The analysis included 18,460 participants aged 8 17 years, with 2,070 diagnosed youth hypertension, defined as blood pressure above 95th percentile for their age gender. Dietary information was collected calculate DII, which initially treated a continuous variable later categorized into tertiles. Multivariable weighted logistic regression restricted cubic spline (RCS) analyses were explore association DII hypertension. results revealed positive higher scores increased likelihood of youth, both RCS showing linear correlation after adjusting potential confounders. findings suggest that managing inflammation may be an important strategy preventing adolescents.

Language: Английский

Citations

0
Inflammatory mechanisms in colorectal cancer: The role of cytokines and dietary inflammatory index : A review DOI Creative Commons

Lana Sarajlić,

Alma Mekić–Abazović, Edin Hodžić

et al.

SANAMED, Journal Year: 2025, Volume and Issue: 00, P. 76 - 76

Published: Jan. 1, 2025

Colorectal cancer is one of the most common malignant tumors, with numerous studies highlighting role inflammation in its onset and progression. Cytokines such as IL-6 TNF-a play a crucial sustaining inflammation, contributing to transformation cells. The dietary inflammatory index, which reflects intake pro-inflammatory nutrients, associated an increased risk developing colorectal cancer. Serum cytokine concentrations may serve biomarkers for assessment, while modifications aimed at reducing can significantly impact both prevention therapy. This knowledge opens possibilities personalized approach treatment

Language: Английский

Citations

0
Association of Dietary Inflammatory Index with Omega-3 Index in Female Athlete DOI Open Access

Mariko Fujibayashi,

Akiko Suganuma,

Masayuki Domichi

et al.

Journal of Nutritional Science and Vitaminology, Journal Year: 2025, Volume and Issue: 71(1), P. 55 - 62

Published: Feb. 27, 2025

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have unique properties that benefit female athletes. No study has examined the association between dietary inflammatory index (DII) and omega-3 index. Therefore, we investigated DII This cross-sectional included university athletes age- sex-matched controls. Data were collected from anthropometric assessments, a food frequency questionnaire (FFQ), blood tests for lipidomics. The energy-adjusted was calculated using FFQ. Seventy-four (mean age=19.7±1.2 y, mean BMI=21.1±2.4) 38 controls age=20.0±0.9 BMI=20.3±2.4) enrolled in study. athlete group tended to higher percentage of high risk/intermediate (75.7% vs. 57.9%; p=0.082) or high-risk category trans-fat (9.5% 0.0%; p=0.093) compared control group. negatively correlated with index, although n-3 PUFA intake did not correlate either present findings indicated might affect independent PUFAs athlete. Health care professionals coach should consider nutritional interventions based on rather than relying solely

Language: Английский

Citations

0
Effect of Preoperative Inflammatory Diet on Clinical and Oncologic Outcomes Following Colorectal Cancer Surgery DOI Open Access
Minjoon Kim, Hae Won Kim, K Kim

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1522 - 1522

Published: April 30, 2025

Objectives: The dietary inflammatory index (DII), a validated tool for assessing the potential of diet, has been widely identified as significant risk factor colorectal cancer (CRC). However, its role prognostic CRC remains unexplored. This study examined impact preoperative inflammation on clinical and oncologic outcomes following surgery. Methods: population consisted 126 patients who had surgical procedures completed food frequency questionnaire (FFQ) preoperatively between January 2018 June 2020. Results: An optimal DII cut-off value 0.90182 was used to categorize into high-DII (n = 28) low-DII 98) groups. group exhibited an older age (71.5 vs. 67.0, p 0.020) significantly higher complication within 30 days postoperatively than (57.1% 35.7%, 0.042). Other perioperative did not demonstrate any differences two 5-year overall survival (OS) rates were 90.4% 41.3% in groups, respectively, univariate analysis (p 0.044). no statistical difference observed disease-free (DFS) rate. In multivariate analysis, (hazard ratio [HR]: 0.118; 95% confidence interval [CI]: 0.023-0.613, 0.011) M1 stage (HR: 10.910; CI: 1.491-79.847, 0.019) independent factors OS, while perineural invasion 3.495; 1.059-11.533, 0.040) served DFS. Conclusions: A high score, indicative pattern, correlated with increased postoperative complications functioned indicator OS.

Language: Английский

Citations

0
Integrative Oncology Approaches to Supporting Immune Checkpoint Inhibitor Treatment of Solid Tumours DOI Creative Commons
Nina Fuller-Shavel, Jonathan Krell

Current Oncology Reports, Journal Year: 2024, Volume and Issue: 26(2), P. 164 - 174

Published: Jan. 9, 2024

Abstract Purpose of Review The goal this review was to examine the role and practical applications integrative oncology strategies in supporting immune checkpoint inhibitor (ICI) treatment adult solid tumours. Recent Findings Beyond tumour-intrinsic factors, several patient-associated factors affect ICI response, including germline genetics, systemic inflammation, gut microbiota, diet. Current promising supportive interventions include a Mediterranean-style diet with over 20 g fibre, regular exercise, use live biotherapeutics, minimisation PPI antibiotic use, ensuring vitamin D repletion, many other approaches under study. Caution around medical cannabis patients on ICIs is advised due previously documented adverse impact overall survival, while VAE ( Viscum album extract) therapy studies have not highlighted any safety concerns so far. Summary With expanding it important investigate apply low-cost support better outcomes minimise events. Further research may lead pre-treatment assessment both tumour biomarkers personalised multimodal prehabilitation care plans, as well on-treatment targeted nutrition, physical activity, supplementation regimes, inflammation microbiome modulating strategies. Given emerging understanding chronic stress outcomes, mind-body require further investigation.

Language: Английский

Citations

3
The Dietary Inflammatory Index and Its Associations with Biomarkers of Nutrients with Antioxidant Potential, a Biomarker of Inflammation and Multiple Long-Term Conditions DOI Creative Commons
Angela A. Mulligan, Marleen A. H. Lentjes, Jane Skinner

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(8), P. 962 - 962

Published: Aug. 8, 2024

We aimed to validate the Dietary Inflammatory Index (DII

Language: Английский

Citations

2
A systematic review and meta-analysis of Dietary Inflammatory Index and the likelihood of multiple sclerosis/ demyelinating autoimmune disease DOI Creative Commons
Esmaeil Yousefi Rad, Somayeh Saboori, Thanasis G. Tektonidis

et al.

Clinical Nutrition ESPEN, Journal Year: 2024, Volume and Issue: 62, P. 108 - 114

Published: May 22, 2024

Diet and inflammation may contribute to the development of multiple sclerosis (MS). The aim this systematic review meta-analysis was assess association between proinflammatory diet, as estimated by Dietary Inflammatory Index (DII®), likelihood developing MS or other demyelinating autoimmune diseases. A search performed engines databases (PubMed, ISI Web Sciences, Scopus, Embase) identify relevant studies before 10th June 2023. identified 182 potential studies, from which 39 full-text articles were screened for relevance. Five with case-control design (n = 4,322, intervention group: 1714; control 2608) met study inclusion criteria. exposure variable DII, using two distinct models: quartile-based comparisons DII assessment continuous DII. high versus low quartiles four effect sizes showed a significant MS/demyelinating disease likelihood, an odds ratio (OR) 3.26 (95% confidence interval (CI) 1.16, 9.10). fit 31% increased per unit increment; not statistically at nominal alpha equals 0.05 (OR 1.31; 95% CI 0.95, 1.81). In conclusion, provides evidence positive higher scores MS, highlighting that diet-induced could play role in diseases risk.

Language: Английский

Citations

1
Maternal pre-pregnancy diet and prenatal depression: the mediating role of pre-pregnancy weight status and prenatal inflammation DOI Open Access
Elnaz Vaghef‐Mehrabany, Rhonda C. Bell, Catherine J. Field

et al.

British Journal Of Nutrition, Journal Year: 2024, Volume and Issue: 132(2), P. 115 - 129

Published: May 27, 2024

Abstract Depression is a common prenatal psychological complication. We aimed to investigate if maternal pre-pregnancy diet can impact depressive symptoms and the mediating role of BMI inflammation. used data ( N 1141) from Alberta Pregnancy Outcomes Nutrition cohort study. calculated Mediterranean adherence (MED) dietary inflammatory index (DII) scores using FFQ. In third-trimester, we assessed Edinburgh Postpartum Scale (EPDS) inflammation through serum C-reactive protein (CRP) levels. was self-reported weight. Race-stratified analyses (white people colour) were run. observed no association between MED or DII tertiles symptoms. However, white participants in tertile-3 had lower risk depression (EPDS < 10) compared with tertile-1 (OR = 0·56, 95 % CI, 0·33, 0·95). White individuals (MD –1·08; −1·77, −0·39) CRP –0·53; −0·95, −0·11) than tertile-1, those tertile-2 0·44; 0·03, 0·84) 0·42; 0·01, 0·83) higher tertile-1. Among colour, neither nor associated CRP, but negatively β –0·25, −0·43, −0·06). found either race. Pre-pregnancy might affect race-specific way. Further research required explore racial differences symptoms/depression risk.

Language: Английский

Citations

1