The relationship between the severity and complications of Henöch-Schönlein purpura in children and dietary inflammatory index: a retrospective cohort study DOI Creative Commons
Jinshu Chen,

P. S. Chen,

Yijin Song

et al.

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e18175 - e18175

Published: Sept. 24, 2024

Purpose To investigate the association between Dietary Inflammatory Index (DII) and disease severity as well complications in children diagnosed with Henöch-Schönlein purpura (HSP), shedding light on potential influence of dietary factors HSP. Methods A retrospective cohort study was conducted, enrolling aged 2–14 years Participants were divided into low Pro-inflammatory groups based their DII scores. Biomarkers, nutrient intake, blood lipid profiles compared two groups. Spearman correlation analysis performed to assess relationship complications. Results total 115 patients, including 56 patients anti-inflammatory 59 pro-inflammatory dietary, included. The group demonstrated significantly elevated C-reactive protein, tumor necrosis factor-α, interleukin-6, erythrocyte sedimentation rate, white cell count, eosinophils, IgE, consumption calories, carbohydrates, fiber, fat cholesterol, LDL HDL triglycerides, VLDL renal, skin, gastrointestinal, coagulation respiratory comparison group. positively correlated Conclusion highlights inflammatory potential, quantified by DII, Understanding interplay patterns responses pediatric vasculitis has implications for management HSP, emphasizing relevance considering interventions optimize clinical outcomes improve overall well-being affected children.

Language: Английский

The relationship between the severity and complications of Henöch-Schönlein purpura in children and dietary inflammatory index: a retrospective cohort study DOI Creative Commons
Jinshu Chen,

P. S. Chen,

Yijin Song

et al.

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e18175 - e18175

Published: Sept. 24, 2024

Purpose To investigate the association between Dietary Inflammatory Index (DII) and disease severity as well complications in children diagnosed with Henöch-Schönlein purpura (HSP), shedding light on potential influence of dietary factors HSP. Methods A retrospective cohort study was conducted, enrolling aged 2–14 years Participants were divided into low Pro-inflammatory groups based their DII scores. Biomarkers, nutrient intake, blood lipid profiles compared two groups. Spearman correlation analysis performed to assess relationship complications. Results total 115 patients, including 56 patients anti-inflammatory 59 pro-inflammatory dietary, included. The group demonstrated significantly elevated C-reactive protein, tumor necrosis factor-α, interleukin-6, erythrocyte sedimentation rate, white cell count, eosinophils, IgE, consumption calories, carbohydrates, fiber, fat cholesterol, LDL HDL triglycerides, VLDL renal, skin, gastrointestinal, coagulation respiratory comparison group. positively correlated Conclusion highlights inflammatory potential, quantified by DII, Understanding interplay patterns responses pediatric vasculitis has implications for management HSP, emphasizing relevance considering interventions optimize clinical outcomes improve overall well-being affected children.

Language: Английский

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