Aromatherapy was used to explore the sedative and hypnotic effects of Moringa seed essential oil on insomnia rats DOI Creative Commons
Shaofeng Wei,

Ruijie Chen,

Xiaoyi Liu

et al.

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(12), P. 10463 - 10476

Published: Nov. 12, 2024

Abstract Moringa is a type of plant that used both for medicinal and food. seed (MS) are rich in volatile oil have initially been employed to treat diseases the nervous system. Insomnia, prevalent neurological disorder, has led this study's aim: extract essential from MS analyze its potential improve sleep. This study utilized petroleum ether thermal extraction MS, which was then subjected compositional analysis using Gas Chromatograph Mass Spectrometer (GC–MS). P‐chlorophenyl alanine (PCPA) induce an insomnia model Sprague–Dawley (SD) rats. Following successful establishment model, administered at concentrations 10%, 5%, 2.5% investigate sedative hypnotic effects. The efficacy assessed by observing general condition rats each group, conducting open field test, pentobarbital sodium righting measuring serum 5‐HT (5‐hydroxytryptamine) levels hypothalamic GABA (γ‐aminobutyric acid) content. GC–MS revealed composition, including oleic acid, palmitoleic stigmasterol, γ‐stigmasterol, among other substances. Through assessment rats' condition, behavioral tests, blood biochemical assays, it inferred aromatherapy can reduce rat's locomotor activity, increase their interest activity exploration, enhance levels, elevate Consequently, be concluded effect.

Language: Английский

Aperiodic and Periodic Components of Resting-state EEG in Primary Insomnia DOI
Duo Bai, Y. Guo, Simon Theodor Jülich

et al.

Sleep Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Aromatherapy was used to explore the sedative and hypnotic effects of Moringa seed essential oil on insomnia rats DOI Creative Commons
Shaofeng Wei,

Ruijie Chen,

Xiaoyi Liu

et al.

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(12), P. 10463 - 10476

Published: Nov. 12, 2024

Abstract Moringa is a type of plant that used both for medicinal and food. seed (MS) are rich in volatile oil have initially been employed to treat diseases the nervous system. Insomnia, prevalent neurological disorder, has led this study's aim: extract essential from MS analyze its potential improve sleep. This study utilized petroleum ether thermal extraction MS, which was then subjected compositional analysis using Gas Chromatograph Mass Spectrometer (GC–MS). P‐chlorophenyl alanine (PCPA) induce an insomnia model Sprague–Dawley (SD) rats. Following successful establishment model, administered at concentrations 10%, 5%, 2.5% investigate sedative hypnotic effects. The efficacy assessed by observing general condition rats each group, conducting open field test, pentobarbital sodium righting measuring serum 5‐HT (5‐hydroxytryptamine) levels hypothalamic GABA (γ‐aminobutyric acid) content. GC–MS revealed composition, including oleic acid, palmitoleic stigmasterol, γ‐stigmasterol, among other substances. Through assessment rats' condition, behavioral tests, blood biochemical assays, it inferred aromatherapy can reduce rat's locomotor activity, increase their interest activity exploration, enhance levels, elevate Consequently, be concluded effect.

Language: Английский

Citations

0