Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study

Metabolites, Journal Year: 2025, Volume and Issue: 15(2), P. 79 - 79

Published: Jan. 29, 2025

Objectives: There are still limited or lacking data on the association of trace elements (TEs) with polycystic ovary syndrome (PCOS). This case–control study aimed to determine levels essential TEs (manganese (Mn), copper (Cu), zinc (Zn), selenium (Se), molybdenum (Mo)) and non-essential (arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb)) in urine, whole blood, serum investigate a possible kidney liver function, endocrine metabolic parameters, environmental lifestyle sources potential exposure provide recommendations. Methods: In our study, women PCOS (n = 35) healthy controls underwent clinical ultrasonographic examination, filled questionnaires targeting general, lifestyle, information, provided fasting venous blood samples first morning urine for biochemical, hormonal, TE analysis. Multiple linear regression models were used evaluate between obtained through questionnaires. Results: PCOS, lower Mo (p 0.024) 0.011) higher Cu 0.026) detected when compared controls. Results this show that amendments might be related altered function disrupted hormonal balance women. positively correlated leukocyte count. was negative correlation proteinuria luteinizing hormone levels. Regarding negatively urinary bilirubin levels, there positive alanine aspartate aminotransferase, respectively. Dietary supplement consumption certain diet habits appeared important predictors (beef consumption) (cereal boiled vegetable modify Conclusions: Concentrations chemical biological appear nutrition. To knowledge, is novel finding Mo. Additional research needed more insights into causality relationship humans.

Language: Английский

Impact of Dietary Antioxidants on Redox Homeostasis and Its Effects on Health and Disease

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2025, Volume and Issue: unknown, P. 81 - 136

Published: Jan. 3, 2025

This chapter discusses the roles of reactive oxygen species (ROS) in cells, including their role oxidative stress and redox balance. It explores how dietary antioxidants affect homeostasis, sources, mechanisms action, antioxidant capacity. The also ROS-mediated signaling cascades endogenous defense mechanisms. use pharmacological approaches to treat chronic illnesses like cancer, neurological disorders, cardiometabolic diseases. addresses paradox, where excessive supplementation can disrupt equilibrium, emphasizing importance balancing pro- antioxidative forces.

Language: Английский