Associations between psychological resilience and metrics of white matter microstructure in pediatric concussion DOI Creative Commons
Olivier Brown, Katherine Healey, Zhuo Fang

et al.

Human Brain Mapping, Journal Year: 2023, Volume and Issue: 44(10), P. 3986 - 3997

Published: May 1, 2023

Abstract This study investigated associations between psychological resilience and characteristics of white matter microstructure in pediatric concussion. is a case control planned substudy larger randomized controlled trial. Children with an acute concussion or orthopedic injury were recruited from the emergency department. Participants completed both Connor–Davidson Resilience Scale 10 MRI at 72 h 4‐weeks post‐injury. The association resiliency fractional anisotropy (FA), mean diffusivity (MD), axial (AD), radial (RD) timepoints examined. We examined whether these moderated by group. captured diffusion tensor imaging metrics 4 weeks was also investigated. Clusters extracted using significance threshold threshold‐free cluster enhancement corrected p < .05. A total 66 children (median (IQR) age = 12.88 (IQR: 11.80–14.36); 47% female) 29 orthopedic‐injury 12.49 11.18–14.01); 41% included. negative correlation identified group FA. Meanwhile, positive correlations MD RD. These findings suggest that associated forceps minor, superior longitudinal fasciculus, anterior thalamic radiation post‐concussion. seems to be neural integrity only phase thus may considered when researching recovery.

Language: Английский

Associations between psychological resilience and metrics of white matter microstructure in pediatric concussion DOI Creative Commons
Olivier Brown, Katherine Healey, Zhuo Fang

et al.

Human Brain Mapping, Journal Year: 2023, Volume and Issue: 44(10), P. 3986 - 3997

Published: May 1, 2023

Abstract This study investigated associations between psychological resilience and characteristics of white matter microstructure in pediatric concussion. is a case control planned substudy larger randomized controlled trial. Children with an acute concussion or orthopedic injury were recruited from the emergency department. Participants completed both Connor–Davidson Resilience Scale 10 MRI at 72 h 4‐weeks post‐injury. The association resiliency fractional anisotropy (FA), mean diffusivity (MD), axial (AD), radial (RD) timepoints examined. We examined whether these moderated by group. captured diffusion tensor imaging metrics 4 weeks was also investigated. Clusters extracted using significance threshold threshold‐free cluster enhancement corrected p < .05. A total 66 children (median (IQR) age = 12.88 (IQR: 11.80–14.36); 47% female) 29 orthopedic‐injury 12.49 11.18–14.01); 41% included. negative correlation identified group FA. Meanwhile, positive correlations MD RD. These findings suggest that associated forceps minor, superior longitudinal fasciculus, anterior thalamic radiation post‐concussion. seems to be neural integrity only phase thus may considered when researching recovery.

Language: Английский

Citations

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