The Impact of COVID-19 Pandemic on the Diagnosis, Treatment, and Outcomes of Colorectal Cancer in Singapore

Medicina, Journal Year: 2025, Volume and Issue: 61(1), P. 138 - 138

Published: Jan. 16, 2025

Background and Objectives: During the COVID-19 pandemic, many countries implemented lockdowns social distancing measures, which may delay early diagnosis of colorectal cancer (CRC). This study aims to review impact pandemic on treatment outcomes CRC. Materials Methods: Patients who underwent colonoscopy or surgery for CRC were included. The was divided into pre-COVID-19 (January 2019-January 2020), (February-May recovery (June-December heightened alert (January-December 2021) periods. Cox regression used model waiting time colonoscopy. Multivariable logistic identified associations between periods incidence diagnosed. characteristics surgical procedures that performed compared across Results: A total 18,662 colonoscopies 1462 in period. Compared period, there a longer during (HR: 0.91; 95% CI: 0.87, 0.94) 0.88; CI 0.85, 0.91). (OR: 1.36; 1.04, 1.77) 1.20; 1.01, 1.43) associated with higher odds diagnosing proportion ASA 4 patients (4.3% vs. 1.3%; p < 0.001) stage (22.2% 16.9%; = required Similarly, emergency surgeries (22% 13.3%; 0.002); diverting stomas (13.5% 10.5%; 0.005), Hartmann's (4.4% 0.4%; Conclusions: metastatic requiring surgery. Healthcare policies should facilitate screening, diagnosis, reduce cancer-related morbidity future pandemics.

Language: Английский

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Understanding excess mortality during COVID in Belgium: the influence of pre-existing health status and social factors

Archives of Public Health, Journal Year: 2025, Volume and Issue: 83(1)

Published: Jan. 23, 2025

Abstract Background This study aims to investigate how pre-existing health status and social background contribute excess mortality during the COVID-19 crisis in Belgium. Methods The population consists of almost 1.4 million adult members Solidaris, second largest insurance fund Pre-existing was identified using care reimbursement data, including medication use. Social characteristics included a proxy for low socio-economic status, nationality origin, living arrangement. Excess measured by computing relative difference between all-cause 2020 or 2021 average yearly 2015–2019. Directly Standardised Mortality Rates (DSMRs) were calculated absolute inequalities. Rate Ratios (MRRs) computed Poisson regression analyses Results DSMRs show that persons with no previous disease experienced significant 2020, like men one, two three diseases women various numbers diseases. specific heterogenous results. After adjusting age, sex characteristics, cancer deficit 17% 9% 2021. For asthma COPD, deficits 10% 3% observed 2021, respectively. Conclusion provides insights into complex dynamics crisis, emphasising need consider individual-level information on jointly.

Language: Английский

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Effect of the COVID-19 pandemic and lockdown on cancer stage distribution and time to treatment initiation using cancer registry data of the Swiss cantons of Zurich and Zug from 2018 to 2021

Journal of Cancer Research and Clinical Oncology, Journal Year: 2025, Volume and Issue: 151(2)

Published: Feb. 21, 2025

Swiss healthcare institutions conducted only urgent procedures during the COVID-19 lockdown, potentially leading to a lack of care for other severe diseases, such as cancer. We examined effects pandemic on cancer stage distribution and time between diagnosis treatment initiation using population-based registry data. The study was based data cantons Zurich Zug from 2018 2021. Cancer analysed descriptively with Pearson's Chi-squared test. Time determined in days by fitting Quasipoisson regression models. For all-cancer colorectal, lung, prostate statistically significant evidence difference stages among incidence years observed. Based models, longer (TTI) observed patients diagnosed 2021 receiving surgery (Rate Ratio = 1.08 [95% confidence interval 1.03, 1.14]) or hormone therapy (1.20 [1.03, 1.40]) compared those 2018/19 therapies. no TTI 2020 any therapies investigated, except chemotherapy shorter (0.92 [0.86, 0.98]). outcomes coincided beginning Switzerland onwards. Short- long-term public system were However, we cannot exclude that implementation new law registration explains part our observations.

Language: Английский

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Impact of the COVID-19 Pandemic on Gut Cancer Admissions and Management: A Comparative Study of Two Pandemic Years to a Similar Pre-Pandemic Period

Healthcare, Journal Year: 2025, Volume and Issue: 13(7), P. 805 - 805

Published: April 3, 2025

Background/Objective: Gastrointestinal tract cancers may have been severely affected by the COVID-19 pandemic. The limitations of digestive endoscopy, fear effect, and restrictions on hospital admissions during pandemic delayed presentation patients to hospitals surgical procedures impacted overall survival. Methods: We conducted an observational, cross-sectional study esophageal, gastric, small bowel, colorectal cancer admitted our between 1 January 2018 31 December 2021. analyzed hospitalization rates, pathological type, onset complications, staging, surgery compared a pre-pandemic period (January 2018-December 2019). Results: During 2018-2021, 1613 with malignant gut tumors were (112 esophageal eso-cardial tumors, 419 gastric 34 bowel 1058 tumors). Admission was reduced 30.3% for 27.6% 17.3% tumors. For higher frequency stenosing palliative gastrostomies noted. More stage III lower rate vascular invasion recorded No differences regarding In slightly more II recorded, but occlusive, bleeding, perforated similar; also, rates similar, two-fold perioperative mortality. survival carcinoma (but no statistical significance), although clear explanation has not emerged. Conclusions: impact included significantly newly diagnosed admissions, carcinomas, mortality carcinoma, trend surprisingly without significance). Future research is necessary assessing long-term impact.

Language: Английский

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Delayed surgery during the Covid-19 pandemic did not affect long-term outcomes of pancreatic adenocarcinoma

Surgical Oncology, Journal Year: 2024, Volume and Issue: 58, P. 102169 - 102169

Published: Nov. 23, 2024

Language: Английский

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Global, regional, and national burden of early-onset colorectal cancer and projection to 2050: An analysis based on the Global Burden of Disease Study 2021

Public Health, Journal Year: 2024, Volume and Issue: 238, P. 245 - 253

Published: Dec. 18, 2024

Language: Английский

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