Latent Classes of Adverse and Benevolent Childhood Experiences in a Multinational Sample of Parents and Their Relation to Parent, Child, and Family Functioning during the COVID-19 Pandemic DOI Open Access
Dylan Johnson, Dillon T. Browne, Robert D. Meade

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(20), P. 13581 - 13581

Published: Oct. 20, 2022

Adverse Childhood Experiences (ACEs) are known to contribute later mental health. Conversely, Benevolent (BCEs) may buffer against health difficulties. The importance of ACEs and BCEs for both parents children be most obvious during periods stress, with potential consequences functioning the family. Subgroups in COVID-19 pandemic were investigated validated relation indices parent, child, family well-being. In May 2020, ACEs/BCEs assessed 547 5-18-year-old from U.K., U.S., Canada, Australia. varying levels identified via latent class analysis. subgroups by examining associations between membership parent child Four classes identified: low-ACEs/high-BCEs, moderate-ACEs/high-BCEs, moderate-ACEs/low-BCEs, high-ACEs/moderate-BCEs. Regardless extent BCEs, there was an increased risk difficulties dysfunction among those reporting moderate-to-high ACEs. Parents' history adversity influence their These findings highlight public interventions preventing early-life adversity.

Language: Английский

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence DOI Creative Commons
Anke B. Witteveen, Susanne Y. Young, Pim Cuijpers

et al.

PLoS Medicine, Journal Year: 2023, Volume and Issue: 20(4), P. e1004206 - e1004206

Published: April 25, 2023

Background There remains uncertainty about the impact of Coronavirus Disease 2019 (COVID-19) pandemic on mental health. This umbrella review provides a comprehensive overview association between and common disorders. We qualitatively summarized evidence from reviews with meta-analyses individual study-data in general population, healthcare workers, specific at-risk populations. Methods findings A systematic search was carried out 5 databases for peer-reviewed prevalence depression, anxiety, post-traumatic stress disorder (PTSD) symptoms during published December 31, until August 12, 2022. identified 123 which 7 provided standardized mean differences (SMDs) either longitudinal pre- to or cross-sectional compared matched pre-pandemic data. Methodological quality rated Assessment Multiple Systematic Reviews checklist scores (AMSTAR 2) instrument generally low moderate. Small but significant increases and/or health were reported people preexisting physical conditions, children (3 reviews; SMDs ranged 0.11 0.28). Mental depression significantly increased periods social restrictions (1 review; 0.41 0.83, respectively) anxiety did not (SMD: 0.26). Increases larger longer-lasting 0.16 0.23) than those (2 reviews: 0.12 0.18). Females showed increase males review: SMD 0.15). In disorders, any patient group, adolescents, students, no found SMD’s ranging −0.16 0.48). 116 pooled rates PTSD 9% 48% across Although heterogeneity studies high largely unexplained, assessment tools cut-offs used, age, sex gender, COVID-19 exposure factors be moderators some reviews. The major limitations are inability quantify explain included shortage within-person data multiple studies. Conclusions small consistent deterioration particularly early has been population chronic somatic Also, associations stronger females younger age groups others. Explanatory individual-level, exposure, time-course scarce inconsistencies For policy research, repeated assessments panels including vulnerable individuals recommended respond current future crises.

Language: Английский

Citations

77
A hidden pandemic? An umbrella review of global evidence on mental health in the time of COVID-19 DOI Creative Commons
Marlee Bower, Scarlett Smout, Amarina Donohoe‐Bales

et al.

Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14

Published: March 8, 2023

Background The mental health impacts of the COVID-19 pandemic remain a public concern. High quality synthesis extensive global literature is needed to quantify this impact and identify factors associated with adverse outcomes. Methods We conducted rigorous umbrella review meta-review present (a) pooled prevalence probable depression, anxiety, stress, psychological distress, post-traumatic (b) standardised mean difference in depression anxiety pre-versus-during period, (c) comprehensive narrative poorer Databases searched included Scopus, Embase, PsycINFO, MEDLINE dated March 2022. Eligibility criteria systematic reviews and/or meta-analyses, published post-November 2019, reporting data English on outcomes during pandemic. Findings Three hundred thirty-eight were included, 158 which incorporated meta-analyses. Meta-review symptoms ranged from 24.4% (95%CI: 18–31%, I 2 : 99.98%) for general populations 41.1% 23–61%, 99.65%) vulnerable populations. Prevalence depressive 22.9% 17–30%, 99.99%) 32.5% 17–52%, 99.35) distress PTSD/PTSS 39.1% 34–44%; 99.91%), 44.2% 32–58%; 99.95%), 18.8% 15–23%; 99.87%), respectively. comparing pre-COVID-19 revealed standard differences 0.20 (95%CI = 0.07–0.33) 0.29 0.12–0.45), Conclusion This first synthesise longitudinal show that significantly higher than pre-COVID-19, provide some evidence adolescents, pregnant postpartum people, those hospitalised experienced heightened health. Policymakers can modify future responses accordingly mitigate such measures

Language: Английский

Citations

70
When the Bough Breaks: A systematic review and meta‐analysis of mental health symptoms in mothers of young children during the COVID‐19 pandemic DOI
Nicole Racine,

Rachel Eirich,

Jessica E. Cooke

et al.

Infant Mental Health Journal, Journal Year: 2021, Volume and Issue: 43(1), P. 36 - 54

Published: Dec. 28, 2021

Parents have experienced considerable challenges and stress during the COVID-19 pandemic, which may impact their well-being. This meta-analysis sought to identify: (1) prevalence of depression anxiety in parents young children (

Language: Английский

Citations

88
Effects of perioperative use of esketamine on postpartum depression risk in patients undergoing cesarean section: A randomized controlled trial DOI Creative Commons
Qingren Liu,

Qian-Kun Zong,

Lili Ding

et al.

Journal of Affective Disorders, Journal Year: 2023, Volume and Issue: 339, P. 815 - 822

Published: July 22, 2023

Postpartum depression (PPD) is a prevalent public health issue. Although ketamine has prophylactic effects on PPD in women undergoing cesarean section, the of esketamine remain unclear. This trial aimed to evaluate efficacy perioperative infusion risk by assessing Edinburgh Postnatal Depression Scale (EPDS) scores and blood biomarkers.A total 150 participants elective section were randomly allocated receive either or normal saline. Since 27 excluded due consent withdrawal loss follow-up, 123 patients included. The primary outcome was prevalence risk. Secondary outcomes included postpartum anxiety (PPA) risk, levels biomarkers, postoperative pain intensity, cumulative sufentanil consumption.The PPA at 3 days, 42 months, 6 months did not differ between two groups. Furthermore, EPDS scores, intensity rest, during coughing days (POD) 1 2 Sufentanil consumption 0-12 h, 12-24 0-24 0-48 h postoperatively significantly lower group compared control group. Blood biomarkers groups POD 3.The sample size small. simply screened, diagnosed.Perioperative administration decrease incidence after section. However, reduced opioid consumption.

Language: Английский

Citations

41
Parental Challenges During the COVID-19 Pandemic: Psychological Outcomes and Risk and Protective Factors DOI Open Access

Grace L. Whaley,

Betty Pfefferbaum

Current Psychiatry Reports, Journal Year: 2023, Volume and Issue: 25(4), P. 165 - 174

Published: March 22, 2023

Language: Английский

Citations

37
A consensus statement on perinatal mental health during the COVID-19 pandemic and recommendations for post-pandemic recovery and re-build DOI Creative Commons
Leanne Jackson, Mari Greenfield,

Elana Payne

et al.

Frontiers in Global Women s Health, Journal Year: 2024, Volume and Issue: 5

Published: Feb. 21, 2024

Introduction The COVID-19 pandemic posed a significant lifecourse rupture, not least to those who had specific physical vulnerabilities the virus, but also were suffering with mental ill health. Women and birthing people pregnant, experienced perinatal bereavement, or in first post-partum year (i.e., perinatal) exposed number of risk factors for health, including alterations way which their care was delivered. Methods A consensus statement derived from cross-disciplinary collaboration experts, whereby evidence collaborative work on health during synthesised, priorities established as recommendations research, healthcare practice, policy. Results synthesis research focused effect outcomes practices led three immediate recommendations: what retain, reinstate, remove provision. Longer-term action made, categorised follows: Equity Relational Healthcare; Parity Esteem Mental Physical Healthcare an Emphasis Specialist Perinatal Services; Horizon Scanning Health Research, Policy, & Practice. Discussion base is growing. This synthesises said makes post-pandemic recovery re-build services

Language: Английский

Citations

10
A Plasma Proteomics-Based Model for Identifying the Risk of Postpartum Depression Using Machine Learning DOI Creative Commons
Shusheng Wang, Ru Xu,

Gang Li

et al.

Journal of Proteome Research, Journal Year: 2025, Volume and Issue: 24(2), P. 824 - 833

Published: Jan. 7, 2025

Postpartum depression (PPD) poses significant risks to maternal and infant health, yet proteomic analyses of PPD-risk women remain limited. This study analyzed plasma samples from 30 healthy postpartum using mass spectrometry, identifying 98 differentially expressed proteins (29 upregulated 69 downregulated). Principal component analysis revealed distinct protein expression profiles between the groups. Functional enrichment PPI further explored biological functions these proteins. Machine learning models (XGBoost LASSO regression) identified 17 key proteins, with optimal logistic regression model comprising P13797 (PLS3), P56750 (CLDN17), O43173 (ST8SIA3), P01593 (IGKV1D-33), P43243 (MATR3). The demonstrated excellent predictive performance through ROC curves, calibration, decision curves. These findings suggest potential biomarkers for early PPD risk assessment, paving way personalized prediction. However, limitations include lack diagnostic interviews, such as Structured Clinical Interview DSM-V (SCID), confirm diagnosis, a small sample size, limited ethnic diversity, affecting generalizability. Future studies should expand diagnoses SCID, validate in larger cohorts ensure their clinical applicability.

Language: Английский

Citations

1
Unexpected changes in birth experiences during the COVID-19 pandemic: Implications for maternal mental health DOI Creative Commons
Cindy H. Liu, Amanda Koire, Carmina Erdei

et al.

Archives of Gynecology and Obstetrics, Journal Year: 2021, Volume and Issue: 306(3), P. 687 - 697

Published: Nov. 1, 2021

Language: Английский

Citations

43
Evaluating depression and anxiety throughout pregnancy and after birth: impact of the COVID-19 pandemic DOI Creative Commons
Cindy X. W. Zhang,

Justin C. Okeke,

Robert D. Levitan

et al.

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2022, Volume and Issue: 4(3), P. 100605 - 100605

Published: March 4, 2022

BACKGROUNDThe COVID-19 pandemic presents unique social, economic, and psychological challenges for individuals globally. Thus, women who are pregnant face unprecedented mental health challenges.OBJECTIVEWe sought to determine the impact of on perinatal depression anxiety in a longitudinal pregnancy cohort. We hypothesized increased scores during after birth at all time points.STUDY DESIGNParticipants were enrolled Ontario Birth Study, cohort embedded clinical care Mount Sinai Hospital, Toronto, Canada. Perinatal assessed using 2-Item Patient Health Questionnaire Generalized Anxiety Disorder early pregnancy, whereas Edinburgh Postnatal Depression Scale used late birth. Logistic regression models created examine association with clinically elevated prepandemic group vs while adjusting covariates.RESULTSA total 1159 survey responses from 649 participants between March 1, 2019, February 28, 2021, conduct this study. Participants (n=416), (n=373), (n=370). Responses received or before 29, 2020, considered "prepandemic" responses, aforementioned date "pandemic" responses. Mean rank significantly higher (P=.02 P=.003, respectively) postpartum period. There was no significant antenatal scores. However, postnatally, mothers 2.6 times more likely score ≥13 than (95% confidence interval, 1.2–5.7; P=.02). Adjustment ethnicity income strengthened as odds ratio 3.3 1.4–8.0; P=.007).CONCLUSIONPandemic-associated increases confined period, highlighting need screening interventions mood disorders postnatally continues. The challenges. points. covariates. A P=.007). Pandemic-associated

Language: Английский

Citations

30
The change of psychosocial stress factors in families with infants and toddlers during the COVID-19 pandemic. A longitudinal perspective on the CoronabaBY study from Germany DOI Creative Commons
Catherine Buechel, Anna Friedmann,

Stefan Eber

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: March 18, 2024

Background Over nearly three years, the COVID-19 pandemic has had a lasting impact on people's lives and mental health worldwide with its far-reaching restrictions concerns about infections other personal consequences. Families were particularly affected showed increased stress psychological problems. Long-term effects cannot be ruled out. So far, data young families are sparse. The present longitudinal analysis ( n = 932) of CoronabaBY study investigated development parenting stress, parental affective symptoms, child's in children aged 0–3 years Germany as well potential influencing factors. Methods observational includes two measurement points over course (baseline follow-up). Data was collected by app using standardized questionnaires. Results N 932 participants, mainly mothers (94.7%) born (93.1%) higher education (61.3% at least high school diploma) comfortable financial situation participated study. Children average 14.7 months old baseline (SD: 12, range: 1–39 months). While proportion parents who perceived stressful decreased significantly from (60%) to follow-up (52.3%), (from 40.1% 45.4%). Both child problems remained constant time, infants crying/feeding/sleeping ranging above pre-pandemic comparative data. Most predictive for baseline. This also true symptoms (depression/anxiety) Conclusions Despite faded restrictions, burdened. Support services do not appear have been sufficient help out their situation. Our results indicate need action regarding low-threshold that effectively reach families. Trial registration pre-registered OSF https://osf.io/search/?q=tksh5&page=1 ).

Language: Английский

Citations

8