Neurotoxicology of Metals DOI

Freeman Lewis,

Somaiyeh Azmoun,

Daniel Shoieb

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Glial Perturbation in Metal Neurotoxicity: Implications for Brain Disorders DOI Creative Commons
Olayemi K. Ijomone, Ukwubile Ileje Inelo, Vivian O. Aneke

et al.

Neuroglia, Journal Year: 2025, Volume and Issue: 6(1), P. 4 - 4

Published: Jan. 6, 2025

Overexposure of humans to heavy metals and essential poses a significant risk for the development neurological neurodevelopmental disorders. The mechanisms through which these exert their effects include generation reactive oxygen species, mitochondrial dysfunction, activation inflammatory pathways, disruption cellular signaling. function glial cells in brain maintenance homeostasis cannot be overlooked. are particularly susceptible metal-induced neurotoxicity. Accumulation promotes microglial activation, triggering responses that can coincide with other neurotoxicity, inducing alteration synaptic transmission, cognitive deficit, neuronal damage. In this review, we highlighted role dysfunction some selected neurodegenerative diseases We further dive into how exposure such as nickel, manganese, methyl mercury, cadmium, iron, arsenic, lead affect functions microglia, astrocytes, oligodendrocytes they on relation Potential therapeutic interventions use new improved chelating agents antioxidant therapies might approach alleviating perturbations.

Language: Английский

Citations

3
Cadmium neurotoxicity: Insights into behavioral effect and neurodegenerative diseases DOI

Kimia Rezaei,

Ghazaleh Mastali, Elham Abbasgholinejad

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 364, P. 143180 - 143180

Published: Aug. 24, 2024

Language: Английский

Citations

5
Toxic Effects and Mechanism of Cadmium-Induced Oxidative Damage in Neuronal Cells DOI

Zhu-Zhong Mei,

Jie Yang, Yuan Zhao

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Syringic acid alleviates cadmium-induced neurotoxicity in rats by modulating cellular signaling pathways DOI
Merve Bolat, Taner Yılmaz,

Murat Çeğindir

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 158, P. 114816 - 114816

Published: May 11, 2025

Language: Английский

Citations

0
Dysregulation of Long Non-coding RNAs—the Novel lnc in Metal Toxicity and Carcinogenesis DOI
Zhishan Wang, Po‐Shun Wang, Chengfeng Yang

et al.

Current Environmental Health Reports, Journal Year: 2024, Volume and Issue: 12(1)

Published: Dec. 23, 2024

Language: Английский

Citations

0
Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2 DOI Creative Commons
Siyao Li,

Mingdan You,

Chengjie Chen

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 290, P. 117620 - 117620

Published: Dec. 27, 2024

Language: Английский

Citations

0
Neurotoxicology of Metals DOI

Freeman Lewis,

Somaiyeh Azmoun,

Daniel Shoieb

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0