Molecular Mechanism of Notch Signaling and Macrophages in Deep Vein Thrombosis: A Comprehensive Review DOI

Shona Joy,

Anusha Prasannan,

Kaliyamurthi Venkatachalam

et al.

Cell Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Language: Английский

Exploring the mechanism and crosstalk between IL-6 and IL- 1β on M2 macrophages under metabolic stress conditions DOI

Shawna Yadav,

Anusha Prasannan,

Kaliyamurthi Venkatachalam

et al.

Cytokine, Journal Year: 2025, Volume and Issue: 186, P. 156852 - 156852

Published: Jan. 6, 2025

Language: Английский

Citations

1

Phycochemistry and pharmacological significance of filamentous cyanobacterium Spirulina sp. DOI Creative Commons

Sheetal Sabat,

Shuvasree Bej,

Surendra Swain

et al.

Bioresources and Bioprocessing, Journal Year: 2025, Volume and Issue: 12(1)

Published: April 3, 2025

Abstract The cyanobacterium , Spirulina sp. is a photosynthetic blue-green alga with essential nutrients, vitamins nucleic acids, proteins, carbohydrates, fatty acids and pigments carotenes; phycocyanins are the significant components having immunomodulatory, anti-inflammatory properties, which used in food cosmetics industries. can play an important role human animal nutrition for potential health benefits due to their phycochemical pharmaceutical significance. This study highlights antibacterial, antifungal, antiviral, antioxidant, nephroprotective, cardioprotective, anticancer, neuroprotective, anti-aging, anti-inflammatory, immunomodulatory properties. It anti-anemic, antidiabetic, probiotic, anti-malarial, anti-obesity weight loss, anti-genotoxicity, anti-thrombic, radioprotective, detoxifying effects of Pharmaceutical studies indicate it may improve heart add treatment diabetes, obesity loss. major protecting environment by recycling wastewater providing humans animals. supply ingredients aquaculture agricultural feeds, pigments, antioxidants, omega-3 oils, among other wellness products. amino acid greatest qualititavely any plant, even higher than that soybean. Furthermore, could be future antimicrobial drug agent. Graphical

Language: Английский

Citations

1

Comparative Assessment of Live and Dead Thermophilic Bacterial Isolates of Surya Kund Hot Spring, Yamunotri for the Bioremediation of Cu 2+ DOI

Shailesh K. Vishwakarma,

Anjali Patil,

Anshika Verma

et al.

Geomicrobiology Journal, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 8

Published: Feb. 27, 2025

Heavy metal pollution, especially copper (Cu2+) contamination, poses significant threats to ecosystems and human health due its persistence, bioaccumulation, toxicity. Traditional methods of remediation are often expensive generate secondary necessitating the exploration eco-friendly alternatives. Bioremediation, leveraging metabolic capabilities microorganisms, offers a promising solution. This study investigates bioremediation potential ions using thermophilic bacterial isolates from Surya Kund Hot Spring in Western Garhwal Himalayas (Uttarakhand). Both live dead cells were tested for their ability remove Cu2+ contaminated solution, showing significantly higher efficiency. Isolates Y12-II (Pseudomonas alloputida strain BG-3) Y10 (Paenibacillus thiaminolyticus NBRC 15656) exhibited highest rates, achieving up 51.97% 50.82% removal, respectively. The findings suggest biomass approach passive heavy contamination. However, recent advancements microbial isolation, genetic engineering, metagenomics have expanded our understanding resistance mechanisms enhanced strategies. reveals as sustainable address contributing environmental restoration public safety.

Language: Английский

Citations

0

Pulmonary Injury Induced via Metal–Organic Frameworks (MOFs): ROS Generation and Inflammatory Responses Mediated by HKUST-1 DOI Creative Commons
Yule Zhang,

Zhiwei Xue,

Zhijin Yang

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Language: Английский

Citations

0

Mechanisms of Copper-Induced Autophagy and Links with Human Diseases DOI Creative Commons
Yuanyuan Fu, Shuyan Zeng, Zhenlin Wang

et al.

Pharmaceuticals, Journal Year: 2025, Volume and Issue: 18(1), P. 99 - 99

Published: Jan. 15, 2025

As a structural and catalytic cofactor, copper is involved in many biological pathways required for the biochemistry of all living organisms. However, excess intracellular can induce cell death due to its potential catalyze generation reactive oxygen species, thus homeostasis strictly regulated. And deficiency or accumulation connected with various pathological conditions. Since success platinum-based compounds clinical treatment types neoplasias, metal-based drugs have shown encouraging perspectives drug development. Compared platinum, an essential trace element that may better prospects development than platinum. Recently, therapeutic role copper-induced autophagy chronic diseases such as Parkinson’s, Wilson’s, cardiovascular disease has already been demonstrated. In brief, ions, numerous complexes, copper-based nano-preparations could autophagy, lysosome-dependent process plays important human diseases. this review, we not only focus on current advances elucidating mechanisms compounds/preparations regulation but also outline association between

Language: Английский

Citations

0

An APTES-modified thiophene-based Schiff base microelectromechanical sensor for the analysis of Cu2+ ions in water: Counterion and pH effects: Experimental and DFT study DOI
Shofiur Rahman,

Mahmoud Al‐Gawati,

Nahed Alarifi

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113325 - 113325

Published: March 1, 2025

Language: Английский

Citations

0

Genome-Wide Association Analysis and Candidate Gene Prediction of Wheat Grain Copper Concentration DOI Creative Commons

Zhaojun Zou,

Xiaofei Liu,

Fengfeng Li

et al.

Agronomy, Journal Year: 2025, Volume and Issue: 15(4), P. 792 - 792

Published: March 24, 2025

Copper (Cu) is an essential micronutrient for almost all organisms; however, the genetic basis regarding copper accumulation remains unclear. In present study, a genome-wide association study (GWAS) was performed on Cu concentration in grains of 207 wheat accessions based five multi-locus models (FASTmrMLM, ISIS EM-BLASSO, mrMLM, pKWmEB, pLARmEB). A total 86 significant quantitative trait nucleotides (QTNs) were identified using methods, with mrMLM model detecting fewest QTNs, only 12, while other four detected 21–40 QTNs. Thirty stable QTNs multiple environments or models, mainly distributed chromosomes 2A, 4B, 2B, and 5A, explaining 0.5–29.3% phenotypic variation. Finally, potential candidate genes associated absorption transport genomic regions near reliable screened out, including TraesCS2A02G505500 TraesCS4B02G019300 (zinc transporters), TraesCS2B02G313200 (copper transporter), TraesCS3A02G042600 TraesCS3B02G040900 (metal tolerance protein). These findings provide new insights into demonstrate role GWAS (ML-GWAS) method.

Language: Английский

Citations

0

Fluorescent Rhodamine Sensors for Mercury, Iron, and Copper Ion Detection in Water: Mechanisms and Applications DOI
Pooja Sahu,

Ajay Patel,

Abhilash Pandey

et al.

Journal of Fluorescence, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Language: Английский

Citations

0

Molecular Mechanism of Notch Signaling and Macrophages in Deep Vein Thrombosis: A Comprehensive Review DOI

Shona Joy,

Anusha Prasannan,

Kaliyamurthi Venkatachalam

et al.

Cell Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Language: Английский

Citations

0