Abstract
Antibiotic
resistance
is
one
of
the
biggest
public
health
problems
our
time.
The
nanoparticles
are
a
powerful
alternative
to
these
antibiotics.
Engineered
show
toxic
effects
on
bacteria
by
different
mechanisms.
bacteria–cell
interaction
engineered
exerts
their
through
changes
in
cell
wall,
membrane,
and
cytoplasm
content/density.
Thus,
death
occurs
as
result
deformation.
In
this
study,
cellular
damage
silver
nanoparticles,
which
known
have
strong
antibacterial
properties,
zirconium
oxide
silicon
engineering
less
known,
periodontopathic
(
Prevotella
intermedia
Aggregatibacter
actinomycetemcomitans
)
bacteria,
were
investigated
ultrastructural
changes.
lysis
separation
membrane
observed.
Both
types
treated
with
Ag
ENP
more
hollow
than
other
two
nanoparticles.
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(8), P. e18960 - e18960
Published: Aug. 1, 2023
Due
to
the
adverse
effects
associated
with
long-term
administration
of
antifungal
drugs
used
for
treating
dermatophytic
lesions
like
tinea
unguium,
there
is
a
critical
need
novel
therapies
that
exhibit
improved
absorption
and
minimal
effects.
Nanoformulations
offer
promising
solution
in
this
regard.
Topical
formulations
may
penetrate
upper
layers
skin,
such
as
stratum
corneum,
release
an
appropriate
amount
therapeutic
quantities.
Liposomes,
particularly
nanosized
ones,
topical
medication
delivery
systems
have
various
roles
depending
on
their
size,
lipid
cholesterol
content,
ingredient
percentage,
lamellarity,
surface
charge.
Liposomes
can
enhance
permeability
through
minimize
systemic
due
localizing
properties,
overcome
challenges
cutaneous
drug
delivery.
Antifungal
medications
encapsulated
liposomes,
including
fluconazole,
ketoconazole,
croconazole,
econazole,
terbinafine
hydrochloride,
tolnaftate,
miconazole,
demonstrated
skin
penetration
localization.
This
review
discusses
traditional
treatment
dermatophytes
liposomal
formulations.
Additionally,
soon
be
available
market
are
introduced.
The
objective
provide
comprehensive
understanding
dermatophyte
infections
role
liposomes
enhancing
treatment.
Journal of Liposome Research,
Journal Year:
2024,
Volume and Issue:
34(4), P. 728 - 743
Published: July 10, 2024
Liver
disorders
present
a
significant
global
health
challenge,
necessitating
the
exploration
of
innovative
treatment
modalities.
Liposomal
nanocarriers
have
emerged
as
promising
candidates
for
targeted
drug
delivery
to
liver.
This
review
offers
comprehensive
examination
mechanisms
and
applications
liposomal
in
addressing
various
liver
disorders.
Firstly
discussing
conventional
approaches,
delves
into
structure
composition.
Moreover,
it
tackles
different
targeting
including
both
passive
active
strategies.
After
that,
moves
on
explore
therapeutic
potentials
treating
cirrhosis,
fibrosis,
viral
hepatitis,
hepatocellular
carcinoma.
Through
recent
advancements
envisioning
future
perspectives,
this
highlights
role
enhancing
effectiveness
safety
consequently
improving
patient
outcomes
enhances
life
quality.
IET Nanobiotechnology,
Journal Year:
2022,
Volume and Issue:
17(1), P. 22 - 31
Published: Nov. 24, 2022
Hyperthermia
is
an
additional
treatment
method
to
radiation
therapy/chemotherapy,
which
increases
the
survival
rate
of
patients
without
side
effects.
Nowadays,
Auroshell
nanoparticles
have
attracted
much
attention
due
their
precise
control
over
heat
use
for
medical
purposes.
In
this
research,
iron/gold
were
synthesised
using
green
nanotechnology
approach.
gold@hematite
and
characterised
with
rosemary
extract
in
one
step
by
X-ray
powder
diffraction,
SEM,
high-resolution
transmission
electron
microscopy,
photoelectron
spectroscopy
analysis.
Cytotoxicity
iron@gold
against
normal
HUVEC
cells
glioblastoma
cancer
was
evaluated
2,5-diphenyl-2H-tetrazolium
bromide
method,
water
bath
hyperthermia,
combined
hyperthermia
nano-therapy.
minimal
toxicity
are
safe
cells.
The
gold
shell
around
magnetic
core
magnetite
caused
environmental
cellular
biocompatibility
these
nanoparticles.
These
targeted
transfer
tumour
tissue
led
uniform
heating
malignant
tumours
as
most
efficient
therapeutic
agent.
Abstract
Antibiotic
resistance
is
one
of
the
biggest
public
health
problems
our
time.
The
nanoparticles
are
a
powerful
alternative
to
these
antibiotics.
Engineered
show
toxic
effects
on
bacteria
by
different
mechanisms.
bacteria–cell
interaction
engineered
exerts
their
through
changes
in
cell
wall,
membrane,
and
cytoplasm
content/density.
Thus,
death
occurs
as
result
deformation.
In
this
study,
cellular
damage
silver
nanoparticles,
which
known
have
strong
antibacterial
properties,
zirconium
oxide
silicon
engineering
less
known,
periodontopathic
(
Prevotella
intermedia
Aggregatibacter
actinomycetemcomitans
)
bacteria,
were
investigated
ultrastructural
changes.
lysis
separation
membrane
observed.
Both
types
treated
with
Ag
ENP
more
hollow
than
other
two
nanoparticles.
