The Innovation Life, Journal Year: 2025, Volume and Issue: unknown, P. 100132 - 100132

Published: Jan. 1, 2025

<p>The intracellular and intercellular information exchange is the key to regulate body function. Current studies have indicated crosstalk between exosomes autophagy as two components of eukaryotic endomembrane system. Exosomes are bilayer lipid membrane vesicles participate in communication. Autophagy form autophagosome, then fuse with lysosome degrade contents encapsulating cytoplasmic components. not only intersect through common molecular mechanism or organelle within cells, but also could activate autophagy-related signaling pathways demonstrate therapeutic potentiality various diseases via exosomal miRNAs proteins. The them serves a homeostatic role mitigating stress. What has become clear that steady state this interaction great significance physiology pathology. If we better understand from more perspectives, such function lipids regulating autophagy, use invertebrates research models relationship selective organelle-level, represents an opportunity for treatment, especially application engineered exosomes.</p>

Language: Английский